fluorouracil has been researched along with Astigmatism in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Astigmatism: Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the mean change in corneal astigmatism and clinical appearance after intralesional injection of 5-Fluorouracil in primary and recurrent pterygia." | 7.83 | Comparison of primary versus recurrent pterygium after intralesional 5-Fluorouracil. ( Basit, I; Khan, MS; Malik, S, 2016) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 7.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "To compare the mean change in corneal astigmatism and clinical appearance after intralesional injection of 5-Fluorouracil in primary and recurrent pterygia." | 3.83 | Comparison of primary versus recurrent pterygium after intralesional 5-Fluorouracil. ( Basit, I; Khan, MS; Malik, S, 2016) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 3.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malik, S | 1 |
| Khan, MS | 1 |
| Basit, I | 1 |
| Sekundo, W | 1 |
| Droutsas, K | 1 |
| Cursiefen, C | 1 |
| Joos, KM | 1 |
| Bueche, MJ | 1 |
| Palmberg, PF | 1 |
| Feuer, WJ | 1 |
| Grajewski, AL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy[NCT00695747] | 95 participants (Actual) | Interventional | 1998-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Astigmatism
| Article | Year |
|---|---|
[Operative techniques for surgical treatment of primary and recurrent pterygia].
Topics: Antimetabolites, Antineoplastic; Astigmatism; Biological Dressings; Combined Modality Therapy; Conju | 2010 |
2 other studies available for fluorouracil and Astigmatism
| Article | Year |
|---|---|
Comparison of primary versus recurrent pterygium after intralesional 5-Fluorouracil.
Topics: Adult; Astigmatism; Drug Administration Schedule; Female; Fluorouracil; Humans; Injections, Intrales | 2016 |
One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction.
Topics: Adult; Aged; Astigmatism; Cataract; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Gl | 1995 |