fluorouracil has been researched along with Asialia in 13 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral pain was assessed using a visual analogue scale alongside assessment of patients' perceptions and daily functional activities based on the Rotterdam Symptom Checklist." | 3.30 | Potential therapeutic effects of different mouthwashes for alleviation and treatment of oral complications of 5-fluorouracil-based chemotherapy in patients with colon cancer. ( Al-Taie, A; Koseoglu, A, 2023) |
| "Although a decrease in distant metastases has frequently been observed, an improvement in survival from induction has been difficult to demonstrate." | 2.43 | Does induction chemotherapy have a role in the management of locoregionally advanced squamous cell head and neck cancer? ( Adelstein, DJ; Leblanc, M, 2006) |
| "Radiotherapy is a common approach for treating squamous cell carcinoma (SCC) of the oropharynx." | 1.43 | Treatment: Outcome and Toxicity of Volumetric Modulated Arc Therapy in Oropharyngeal Carcinoma. ( Clerici, E; Cozzi, L; D'Agostino, G; Fogliata, A; Franceschini, D; Franzese, C; Mancosu, P; Navarria, P; Scorsetti, M; Tomatis, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Nguyen, TV | 1 |
| Chiu, KC | 1 |
| Shih, YH | 1 |
| Liu, CJ | 1 |
| Bao Quach, TV | 1 |
| Hsia, SM | 1 |
| Chen, YH | 1 |
| Shieh, TM | 1 |
| Al-Taie, A | 1 |
| Koseoglu, A | 1 |
| Barbosa, SCM | 1 |
| Pereira, VBM | 1 |
| Wong, DVT | 1 |
| Santana, APM | 1 |
| Lucetti, LT | 1 |
| Carvalho, LL | 1 |
| Barbosa, CRN | 1 |
| Callado, RB | 1 |
| Silva, CAA | 1 |
| Lopes, CDH | 1 |
| Brito, GAC | 1 |
| Alencar, NMN | 1 |
| Lima-Júnior, RCP | 1 |
| Hitomi, S | 1 |
| Ujihara, I | 1 |
| Sago-Ito, M | 1 |
| Nodai, T | 1 |
| Shikayama, T | 1 |
| Inenaga, K | 1 |
| Ono, K | 1 |
| Franzese, C | 1 |
| Fogliata, A | 1 |
| Franceschini, D | 1 |
| Clerici, E | 1 |
| D'Agostino, G | 1 |
| Navarria, P | 1 |
| Mancosu, P | 1 |
| Tomatis, S | 1 |
| Cozzi, L | 1 |
| Scorsetti, M | 1 |
| Yu, Z | 1 |
| Luo, W | 1 |
| Zhou, QC | 1 |
| Zhang, QH | 1 |
| Kang, DH | 1 |
| Liu, MZ | 1 |
| Frikha, M | 1 |
| Toumi, N | 1 |
| Ghorbel, L | 1 |
| Ben Salah, H | 1 |
| Khabir, A | 1 |
| Karray, H | 1 |
| Gargouri, R | 1 |
| Boudawara, T | 1 |
| Ghorbel, A | 1 |
| Daoud, J | 1 |
| Aguilar-Ponce, JL | 1 |
| Granados-García, M | 1 |
| Cruz López, JC | 1 |
| Maldonado-Magos, F | 1 |
| Alvarez-Avitia, MA | 1 |
| Arrieta, O | 1 |
| González-Ramírez, I | 1 |
| Lara-Cruz, G | 1 |
| Martinez-Juárez, I | 1 |
| Medina-Santillan, R | 1 |
| Castillo-Hernández, C | 1 |
| De la Garza-Salazar, J | 1 |
| Corry, J | 1 |
| Peters, L | 1 |
| Kleid, S | 1 |
| Rischin, D | 1 |
| Liu, WS | 1 |
| Su, MC | 1 |
| Wu, MF | 1 |
| Tseng, HC | 1 |
| Kuo, HC | 1 |
| Adelstein, DJ | 1 |
| Leblanc, M | 1 |
| Allen, AM | 1 |
| Elshaikh, M | 1 |
| Worden, FP | 1 |
| Bradford, CR | 1 |
| Teknos, TN | 1 |
| Chepeha, DB | 1 |
| Tsien, C | 1 |
| Dawson, LA | 1 |
| Urba, S | 1 |
| Wolf, GT | 1 |
| Normolle, D | 1 |
| Eisbruch, A | 1 |
| Kagan, AR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter and Prospective Clinical Trial of Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma[NCT04522050] | Phase 1 | 65 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Asialia
| Article | Year |
|---|---|
Does induction chemotherapy have a role in the management of locoregionally advanced squamous cell head and neck cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Hu | 2006 |
2 trials available for fluorouracil and Asialia
| Article | Year |
|---|---|
Potential therapeutic effects of different mouthwashes for alleviation and treatment of oral complications of 5-fluorouracil-based chemotherapy in patients with colon cancer.
Topics: Benzydamine; Colonic Neoplasms; Fluorouracil; Glutamine; Humans; Mouthwashes; Pain; Prospective Stud | 2023 |
Acceleration of hyperfractionated chemoradiation regimen for advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Squamous Cell; | 2007 |
10 other studies available for fluorouracil and Asialia
| Article | Year |
|---|---|
Protective Effect of Electroacupuncture on Chemotherapy-Induced Salivary Gland Hypofunction in a Mouse Model.
Topics: Animals; Antineoplastic Agents; Electroacupuncture; Fluorouracil; Immunoglobulin A, Secretory; Mice; | 2023 |
Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation.
Topics: Amifostine; Animals; Cricetinae; Disease Models, Animal; Fluorouracil; Inflammation; Male; Protectiv | 2019 |
Hyposalivation due to chemotherapy exacerbates oral ulcerative mucositis and delays its healing.
Topics: Animals; Antineoplastic Agents; Cisplatin; Fluorouracil; Mucositis; Rats; Salivary Glands; Sublingua | 2019 |
Treatment: Outcome and Toxicity of Volumetric Modulated Arc Therapy in Oropharyngeal Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2016 |
[Impact of changing gross tumor volume delineation of intensity-modulated radiotherapy on the dose distribution and clinical treatment outcome after induction chemotherapy for the primary locoregionally advanced nasopharyngeal carcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Female; Fl | 2009 |
[Pediatric nasopharyngeal carcinoma: Anatomoclinic aspects, therapeutic results and evolutive particularities].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Chemotherapy, Adju | 2010 |
Alternating chemotherapy: gemcitabine and cisplatin with concurrent radiotherapy for treatment of advanced head and neck cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 2013 |
Larynx preservation for patients with locally advanced laryngeal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy, Adjuvan | 2013 |
Nasopharyngeal carcinoma treated with precision-oriented radiation therapy techniques including intensity-modulated radiotherapy: preliminary results.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dose Fractionation, Radiati | 2004 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; | 1971 |