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fluorouracil and Arterial Occlusive Diseases

fluorouracil has been researched along with Arterial Occlusive Diseases in 16 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.

Research Excerpts

ExcerptRelevanceReference
"After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism."7.76Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010)
"After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism."3.76Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010)
"The 24 patients with advanced colorectal cancer were divided into 2 groups randomly and both were treated with 5-FU 250 mg/day by continuous hepatic arterial infusion for three weeks."2.69[Method of preventing hepatic artery occlusion during continuous intrahepatic arterial infusion chemotherapy of 5-FU]. ( Ishida, H; Ishikawa, K; Itoh, I; Iwase, H; Kameya, T; Makuuchi, H; Mukai, M; Ohtaki, M; Sadahiro, S; Suzuki, T; Tajima, T; Tokunaga, N; Yasuda, S, 1998)
" There seemed to be no correlation with the total dosage of 5-FU or the number of administrations."1.30[Complication due to arterial infusion chemotherapy for liver metastasis from colorectal cancer]. ( Hamada, H; Hashimoto, M; Katsuki, Y; Kawata, S; Kon, H; Sasaki, R; Tomita, I; Tsuji, Y; Yasuda, T, 1997)
"Arterial thrombosis is also associated with multiagent chemotherapy in patients with breast cancer."1.28Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study. ( Korzun, AH; Norton, L; Perloff, M; Rice, MA; Wall, JG; Weiss, RB; Wood, WC, 1989)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's3 (18.75)18.2507
2000's6 (37.50)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doganci, S1
Kadan, M1
Kaya, E1
Erol, G1
Gunay, C1
Demirkilic, U1
Yamagami, T1
Yoshimatsu, R1
Tanaka, T1
Tsuji, K1
Miura, H1
Tanaka, O1
Nishimura, T1
Heinrich, N1
Born, M1
Hoebert, E1
Verrel, F1
Simon, A1
Bode, U1
Fleischhack, G1
Hildebrandt, B1
Meyer, L1
Bechstein, WO1
Puls, R1
Arnold, D1
Bartels, B1
Stroszczynski, C1
Neuhaus, P1
Riess, H1
Barnett, KT1
Malafa, MP1
Maruyama, S1
Aoki, T2
Inoue, K1
Tsuchida, A1
Ozawa, T1
Saito, H1
Hashimoto, T1
Koyanagi, Y1
Tsuji, Y1
Hamada, H1
Katsuki, Y1
Hashimoto, M1
Tomita, I1
Kon, H1
Sasaki, R1
Kawata, S1
Yasuda, T1
Sadahiro, S2
Mukai, M1
Tokunaga, N2
Ishida, H1
Suzuki, T2
Ishikawa, K1
Iwase, H1
Kameya, T1
Itoh, I1
Yasuda, S1
Tajima, T2
Makuuchi, H2
Ohtaki, M2
Asami, S1
Kitahara, K1
Yamaguchi, K1
Ohashi, Y1
Miyashita, K1
Guseinov, E1
Horák, D1
Titova, M1
Adamyan, A1
Kokov, L1
Kubishkin, V1
Vishnevskii, V1
Skuba, N1
Trostenyuk, N1
Antonovic, R1
Rösch, J1
Dotter, CT1
Wall, JG1
Weiss, RB1
Norton, L1
Perloff, M1
Rice, MA1
Korzun, AH1
Wood, WC1
Akamatsu, H1
Kodaira, S1
Teramoto, T1
Arisawa, Y1
Takabayashi, T1
Nakayama, T1
Abe, O1
Goldberg, JA1
Lieberman, DP1
McArdle, CS1

Reviews

2 reviews available for fluorouracil and Arterial Occlusive Diseases

ArticleYear
Complications of hepatic artery infusion: a review of 4580 reported cases.
    International journal of gastrointestinal cancer, 2001, Volume: 30, Issue:3

    Topics: Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Bone Marrow Diseases; Catheters, Indwe

2001
[Complications of hepatic artery chemotherapy for liver metastases in colorectal cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cholangitis, Sclerosing

2003

Trials

4 trials available for fluorouracil and Arterial Occlusive Diseases

ArticleYear
Continuation of regional chemotherapy of hepatic neoplasms despite occlusion of the hepatic artery-report of four cases.
    Anti-cancer drugs, 2002, Volume: 13, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arterial Occlusive Diseases; Catheterization

2002
[A study of various complications in arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Catheters, Indwelling;

1994
[Method of preventing hepatic artery occlusion during continuous intrahepatic arterial infusion chemotherapy of 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:9

    Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Colorectal N

1998
Prevention of hepatic artery occlusion during continuous infusion of fluorouracil using liposteroid.
    AJR. American journal of roentgenology, 2000, Volume: 175, Issue:6

    Topics: Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Colorectal Neoplasms; Dexamethasone; F

2000

Other Studies

10 other studies available for fluorouracil and Arterial Occlusive Diseases

ArticleYear
Acute arterial thrombosis following chemotherapy in a patient with a gastric carcinoma.
    Cardiovascular journal of Africa, 2013, Mar-23, Volume: 24, Issue:2

    Topics: Acute Disease; Adult; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlu

2013
Implantation of port-catheter system for hepatic arterial infusion chemotherapy with catheter tip fixation in a patient with celiac arterial obstruction.
    Journal of vascular and interventional radiology : JVIR, 2010, Volume: 21, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Carcinoma, Hepato

2010
Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma.
    VASA. Zeitschrift fur Gefasskrankheiten, 2010, Volume: 39, Issue:3

    Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aortic Diseases; Arterial O

2010
[Complication due to arterial infusion chemotherapy for liver metastasis from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Choles

1997
[Complications related to arterial infusion chemotherapy in patients with hepatic metastasis from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Adult; Aged; Arterial Occlusive Diseases; Biliary Fistula; Colorectal Neoplasms; Common Bile Duct; E

2000
Endovascular occlusion of branches of hepatic artery with poly(2-hydroxyethyl methacrylate) emboli as a single occlusive measure in hepatology.
    Polimery w medycynie, 2000, Volume: 30, Issue:3-4

    Topics: Abdominal Neoplasms; Adolescent; Adult; Aged; Arterial Occlusive Diseases; Carcinoid Tumor; Carcinom

2000
Complications of percutaneous transaxillary catheterization for arteriography and selective chemotherapy.
    AJR. American journal of roentgenology, 1976, Volume: 126, Issue:2

    Topics: Adult; Aged; Angiography; Aortography; Arterial Occlusive Diseases; Axillary Artery; Catheterization

1976
Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study.
    The American journal of medicine, 1989, Volume: 87, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Breast Neoplasms;

1989
[Hepatic arterial infusion chemotherapy using totally implantable reservoir in liver metastases in colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Carcinoemb

1989
Salvage of blocked hepatic artery infusion catheters for regional therapy of metastatic liver disease.
    The British journal of surgery, 1988, Volume: 75, Issue:5

    Topics: Arterial Occlusive Diseases; Catheters, Indwelling; Chemotherapy, Cancer, Regional Perfusion; Coloni

1988