fluorouracil has been researched along with Arterial Occlusive Diseases in 16 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism." | 7.76 | Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010) |
| "After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism." | 3.76 | Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010) |
| "The 24 patients with advanced colorectal cancer were divided into 2 groups randomly and both were treated with 5-FU 250 mg/day by continuous hepatic arterial infusion for three weeks." | 2.69 | [Method of preventing hepatic artery occlusion during continuous intrahepatic arterial infusion chemotherapy of 5-FU]. ( Ishida, H; Ishikawa, K; Itoh, I; Iwase, H; Kameya, T; Makuuchi, H; Mukai, M; Ohtaki, M; Sadahiro, S; Suzuki, T; Tajima, T; Tokunaga, N; Yasuda, S, 1998) |
| " There seemed to be no correlation with the total dosage of 5-FU or the number of administrations." | 1.30 | [Complication due to arterial infusion chemotherapy for liver metastasis from colorectal cancer]. ( Hamada, H; Hashimoto, M; Katsuki, Y; Kawata, S; Kon, H; Sasaki, R; Tomita, I; Tsuji, Y; Yasuda, T, 1997) |
| "Arterial thrombosis is also associated with multiagent chemotherapy in patients with breast cancer." | 1.28 | Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study. ( Korzun, AH; Norton, L; Perloff, M; Rice, MA; Wall, JG; Weiss, RB; Wood, WC, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doganci, S | 1 |
| Kadan, M | 1 |
| Kaya, E | 1 |
| Erol, G | 1 |
| Gunay, C | 1 |
| Demirkilic, U | 1 |
| Yamagami, T | 1 |
| Yoshimatsu, R | 1 |
| Tanaka, T | 1 |
| Tsuji, K | 1 |
| Miura, H | 1 |
| Tanaka, O | 1 |
| Nishimura, T | 1 |
| Heinrich, N | 1 |
| Born, M | 1 |
| Hoebert, E | 1 |
| Verrel, F | 1 |
| Simon, A | 1 |
| Bode, U | 1 |
| Fleischhack, G | 1 |
| Hildebrandt, B | 1 |
| Meyer, L | 1 |
| Bechstein, WO | 1 |
| Puls, R | 1 |
| Arnold, D | 1 |
| Bartels, B | 1 |
| Stroszczynski, C | 1 |
| Neuhaus, P | 1 |
| Riess, H | 1 |
| Barnett, KT | 1 |
| Malafa, MP | 1 |
| Maruyama, S | 1 |
| Aoki, T | 2 |
| Inoue, K | 1 |
| Tsuchida, A | 1 |
| Ozawa, T | 1 |
| Saito, H | 1 |
| Hashimoto, T | 1 |
| Koyanagi, Y | 1 |
| Tsuji, Y | 1 |
| Hamada, H | 1 |
| Katsuki, Y | 1 |
| Hashimoto, M | 1 |
| Tomita, I | 1 |
| Kon, H | 1 |
| Sasaki, R | 1 |
| Kawata, S | 1 |
| Yasuda, T | 1 |
| Sadahiro, S | 2 |
| Mukai, M | 1 |
| Tokunaga, N | 2 |
| Ishida, H | 1 |
| Suzuki, T | 2 |
| Ishikawa, K | 1 |
| Iwase, H | 1 |
| Kameya, T | 1 |
| Itoh, I | 1 |
| Yasuda, S | 1 |
| Tajima, T | 2 |
| Makuuchi, H | 2 |
| Ohtaki, M | 2 |
| Asami, S | 1 |
| Kitahara, K | 1 |
| Yamaguchi, K | 1 |
| Ohashi, Y | 1 |
| Miyashita, K | 1 |
| Guseinov, E | 1 |
| Horák, D | 1 |
| Titova, M | 1 |
| Adamyan, A | 1 |
| Kokov, L | 1 |
| Kubishkin, V | 1 |
| Vishnevskii, V | 1 |
| Skuba, N | 1 |
| Trostenyuk, N | 1 |
| Antonovic, R | 1 |
| Rösch, J | 1 |
| Dotter, CT | 1 |
| Wall, JG | 1 |
| Weiss, RB | 1 |
| Norton, L | 1 |
| Perloff, M | 1 |
| Rice, MA | 1 |
| Korzun, AH | 1 |
| Wood, WC | 1 |
| Akamatsu, H | 1 |
| Kodaira, S | 1 |
| Teramoto, T | 1 |
| Arisawa, Y | 1 |
| Takabayashi, T | 1 |
| Nakayama, T | 1 |
| Abe, O | 1 |
| Goldberg, JA | 1 |
| Lieberman, DP | 1 |
| McArdle, CS | 1 |
2 reviews available for fluorouracil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
Complications of hepatic artery infusion: a review of 4580 reported cases.
Topics: Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Bone Marrow Diseases; Catheters, Indwe | 2001 |
[Complications of hepatic artery chemotherapy for liver metastases in colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cholangitis, Sclerosing | 2003 |
4 trials available for fluorouracil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
Continuation of regional chemotherapy of hepatic neoplasms despite occlusion of the hepatic artery-report of four cases.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arterial Occlusive Diseases; Catheterization | 2002 |
[A study of various complications in arterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Catheters, Indwelling; | 1994 |
[Method of preventing hepatic artery occlusion during continuous intrahepatic arterial infusion chemotherapy of 5-FU].
Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Colorectal N | 1998 |
Prevention of hepatic artery occlusion during continuous infusion of fluorouracil using liposteroid.
Topics: Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Colorectal Neoplasms; Dexamethasone; F | 2000 |
10 other studies available for fluorouracil and Arterial Occlusive Diseases
| Article | Year |
|---|---|
Acute arterial thrombosis following chemotherapy in a patient with a gastric carcinoma.
Topics: Acute Disease; Adult; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlu | 2013 |
Implantation of port-catheter system for hepatic arterial infusion chemotherapy with catheter tip fixation in a patient with celiac arterial obstruction.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Carcinoma, Hepato | 2010 |
Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aortic Diseases; Arterial O | 2010 |
[Complication due to arterial infusion chemotherapy for liver metastasis from colorectal cancer].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arterial Occlusive Diseases; Choles | 1997 |
[Complications related to arterial infusion chemotherapy in patients with hepatic metastasis from colorectal cancer].
Topics: Adult; Aged; Arterial Occlusive Diseases; Biliary Fistula; Colorectal Neoplasms; Common Bile Duct; E | 2000 |
Endovascular occlusion of branches of hepatic artery with poly(2-hydroxyethyl methacrylate) emboli as a single occlusive measure in hepatology.
Topics: Abdominal Neoplasms; Adolescent; Adult; Aged; Arterial Occlusive Diseases; Carcinoid Tumor; Carcinom | 2000 |
Complications of percutaneous transaxillary catheterization for arteriography and selective chemotherapy.
Topics: Adult; Aged; Angiography; Aortography; Arterial Occlusive Diseases; Axillary Artery; Catheterization | 1976 |
Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Breast Neoplasms; | 1989 |
[Hepatic arterial infusion chemotherapy using totally implantable reservoir in liver metastases in colorectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Carcinoemb | 1989 |
Salvage of blocked hepatic artery infusion catheters for regional therapy of metastatic liver disease.
Topics: Arterial Occlusive Diseases; Catheters, Indwelling; Chemotherapy, Cancer, Regional Perfusion; Coloni | 1988 |