Page last updated: 2024-10-27

fluorouracil and Arterial Inflammation

fluorouracil has been researched along with Arterial Inflammation in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"All of the gallbladders had significant arteritis, with narrowing or occlusion of lumina or necrosis of vessel walls."1.27Chemical cholecystitis associated with hepatic arterial chemotherapy delivered by a permanently implanted pump. ( Dakhil, SR; Housholder, DF; Marymont, JV; Travers, H, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sudoh, M1
Kishimoto, Y1
Marumoto, A1
Inoue, M1
Sano, A1
Miura, N1
Horie, Y1
Hasegawa, J1
Ryoke, K1
Marymont, JV1
Dakhil, SR1
Travers, H1
Housholder, DF1

Other Studies

2 other studies available for fluorouracil and Arterial Inflammation

ArticleYear
A new animal model of continuous catheterization for investigating mechanisms of arteritis associated with chemotherapy.
    Life sciences, 2004, Apr-30, Volume: 74, Issue:24

    Topics: Animals; Antineoplastic Agents; Aorta, Abdominal; Apoptosis; Arteritis; Catheterization; Endothelium

2004
Chemical cholecystitis associated with hepatic arterial chemotherapy delivered by a permanently implanted pump.
    Human pathology, 1985, Volume: 16, Issue:10

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Arteritis; Carcinoma, Hepatocellular; Cholecystitis; Ch

1985