Page last updated: 2024-10-27

fluorouracil and Arenaviridae Infections

fluorouracil has been researched along with Arenaviridae Infections in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Arenaviridae Infections: Virus diseases caused by the ARENAVIRIDAE.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ruiz-Jarabo, CM1
Ly, C1
Domingo, E2
de la Torre, JC2
Grande-Pérez, A1
Lázaro, E1
Lowenstein, P1
Manrubia, SC1

Reviews

1 review available for fluorouracil and Arenaviridae Infections

ArticleYear
Arenavirus extinction through lethal mutagenesis.
    Virus research, 2005, Volume: 107, Issue:2

    Topics: Animals; Antiviral Agents; Arenaviridae Infections; Arenavirus; Cell Line; Fluorouracil; Humans; Lym

2005

Other Studies

2 other studies available for fluorouracil and Arenaviridae Infections

ArticleYear
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).
    Virology, 2003, Mar-30, Volume: 308, Issue:1

    Topics: Animals; Antiviral Agents; Arenaviridae Infections; B-Lymphocytes; Cell Line; Cricetinae; DNA-Bindin

2003
Suppression of viral infectivity through lethal defection.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-22, Volume: 102, Issue:12

    Topics: Animals; Arenaviridae Infections; Biological Evolution; Cell Line; Chlorocebus aethiops; Cricetinae;

2005