fluorouracil has been researched along with Aqueductal Stenosis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with HER2-positive breast cancer, cerebral metastasis sometimes occurs even if the breast tumor and liver/lung metastasis are controlled with trastuzumab." | 5.38 | [A case of HER2-positive breast cancer receiving lapatinib+capecitabine chemotherapy with ventriculoperitoneal shunting for hydrocephalus associated with brain metastases]. ( Kato, Y; Kawamura, H; Makino, T; Nishina, M; Yokoyama, E, 2012) |
| "In patients with HER2-positive breast cancer, cerebral metastasis sometimes occurs even if the breast tumor and liver/lung metastasis are controlled with trastuzumab." | 1.38 | [A case of HER2-positive breast cancer receiving lapatinib+capecitabine chemotherapy with ventriculoperitoneal shunting for hydrocephalus associated with brain metastases]. ( Kato, Y; Kawamura, H; Makino, T; Nishina, M; Yokoyama, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Makino, T | 1 |
| Kawamura, H | 1 |
| Yokoyama, E | 1 |
| Kato, Y | 1 |
| Nishina, M | 1 |
| Takeda, K | 1 |
| Oritsu, M | 1 |
| Sakuta, M | 1 |
2 other studies available for fluorouracil and Aqueductal Stenosis
| Article | Year |
|---|---|
[A case of HER2-positive breast cancer receiving lapatinib+capecitabine chemotherapy with ventriculoperitoneal shunting for hydrocephalus associated with brain metastases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deo | 2012 |
[A case of coccidioidomycosis with central nervous system involvement].
Topics: Adult; Chronic Disease; Coccidioides; Coccidioidomycosis; Fluorouracil; Humans; Hydrocephalus; Male; | 1993 |