Page last updated: 2024-10-27

fluorouracil and Aprosodia

fluorouracil has been researched along with Aprosodia in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"1-Hexylcarbamoyl-5-fluorouracil (HCFU) was administered orally to 63 patients with hepatocellular carcinoma (HCC) at a daily dose of 200 to 600 mg."7.67[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma]. ( Abe, M; Hirai, K; Kubo, Y; Majima, Y; Ninomiya, F; Sakai, T; Sakemi, T; Sato, K; Shiraishi, K; Tanikawa, K, 1984)
"1-Hexylcarbamoyl-5-fluorouracil (HCFU) was administered orally to 63 patients with hepatocellular carcinoma (HCC) at a daily dose of 200 to 600 mg."3.67[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma]. ( Abe, M; Hirai, K; Kubo, Y; Majima, Y; Ninomiya, F; Sakai, T; Sakemi, T; Sato, K; Shiraishi, K; Tanikawa, K, 1984)
"Capecitabine is an oral fluoropyrimidine used for cancer treatment."1.32Capecitabine-related neurotoxicity presenting as trismus. ( Couch, LS; Groteluschen, DL; Mulkerin, DL; Stewart, JA, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lowry, LE1
Fenderson, JL1
Baur, RA1
Denaro, N1
Russi, EG1
Merlano, MC1
Couch, LS1
Groteluschen, DL1
Stewart, JA1
Mulkerin, DL1
Shiraishi, K1
Kubo, Y1
Majima, Y1
Sato, K1
Sakemi, T1
Sakai, T1
Hirai, K1
Ninomiya, F1
Abe, M1
Tanikawa, K1

Other Studies

4 other studies available for fluorouracil and Aprosodia

ArticleYear
Not All That Slurs Is Stroke: A Case of Chemotherapy-Induced Leukoencephalopathy.
    Journal of oncology practice, 2019, Volume: 15, Issue:1

    Topics: Aged; Fluorouracil; Humans; Leukoencephalopathies; Male; Speech Disorders

2019
Strategies for non-resectable head and neck cancer.
    Current treatment options in oncology, 2013, Volume: 14, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2013
Capecitabine-related neurotoxicity presenting as trismus.
    Clinical colorectal cancer, 2003, Volume: 3, Issue:2

    Topics: Antimetabolites, Antineoplastic; Capecitabine; Central Nervous System; Confusion; Deoxycytidine; Dia

2003
[Clinical evaluation of 1-hexylcarbamoyl-5-fluorouracil (HCFU) in hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Female; Fluorou

1984