fluorouracil has been researched along with Appendiceal Cancer in 77 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The patients included were 145 who had colorectal or appendiceal carcinomatosis resected using cytoreductive surgery prior to treatment with hyperthermic intraperitoneal chemotherapy with mitomycin C as part of a multidrug regimen." | 7.77 | Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis. ( Chang, D; Mahteme, H; Stuart, OA; Sugarbaker, PH; Van der Speeten, K, 2011) |
| "Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix." | 7.68 | Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990) |
| "In this prospective randomized crossover trial of systemic chemotherapy in patients with low-grade mucinous appendiceal adenocarcinoma, patients did not derive clinical benefit from fluorouracil-based chemotherapy, given there were no objective responses, no difference in OS when treatment was delayed 6 months, and no difference in the rate of tumor growth while receiving chemotherapy." | 5.69 | Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma: A Randomized Crossover Trial. ( Beaty, KA; Eng, C; Foo, WC; Fournier, K; Hornstein, N; Lano, E; Mansfield, P; Matamoros, A; Overman, MJ; Rafeeq, S; Raghav, KP; Scally, C; Scofield, LC; Shen, JP; Taggart, M; Tidwell, RS; Uppal, A; Yousef, AM; Zeineddine, FA; Zeineddine, MA, 2023) |
| "The patients included were 145 who had colorectal or appendiceal carcinomatosis resected using cytoreductive surgery prior to treatment with hyperthermic intraperitoneal chemotherapy with mitomycin C as part of a multidrug regimen." | 3.77 | Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis. ( Chang, D; Mahteme, H; Stuart, OA; Sugarbaker, PH; Van der Speeten, K, 2011) |
| "By modulating the route or timing of administration of 5-fluorouracil, it becomes a pharmacologic advantageous molecule in patients with peritoneal carcinomatosis of an appendiceal malignancy." | 3.76 | Pharmacology of perioperative 5-fluorouracil. ( Mahteme, H; Stuart, OA; Sugarbaker, PH; Van der Speeten, K, 2010) |
| "Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix." | 3.68 | Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990) |
| "There were 51 patients with colorectal cancer and 130 patients with appendiceal cancer." | 2.68 | Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy. ( Jablonski, KA; Sugarbaker, PH, 1995) |
| "BACKGROUND Gastric cancer metastasis to the appendix is a rare condition that might present with symptoms of acute appendicitis or remain asymptomatic and be diagnosed incidentally." | 2.66 | Missed Gastric Cancer Metastasis to the Appendix: Case Report and Literature Review. ( Aburahmah, M; Alhadid, D; Almana, H; AlShammari, A, 2020) |
| "Certainly in treatment of the carcinoid tumor surgery has a well-established curative and palliative potential." | 2.36 | Treatment of the carcinoid tumor and the malignant carcinoid syndrome. ( Moertel, CG, 1983) |
| "Adenocarcinoma ex-goblet cell carcinoids (AGCCs) are rare appendiceal tumors with mixed neuroendocrine and glandular features." | 1.51 | Adenocarcinoma Ex-Goblet Cell: a Retrospective Experience. ( Berlin, J; Das, S; Du, L; Idrees, K; Shi, C, 2019) |
| "No recurrent inguinal hernias were recorded and no patients required an inguinal incision at a later time to resect progressive disease within the inguinal canal." | 1.46 | Management of an inguinal hernia in patients with pseudomyxoma peritonei. ( Sugarbaker, PH, 2017) |
| "Appendix cancer was diagnosed intraoperatively." | 1.42 | [A case of appendix cancer treated as cancer of unknown primary origin]. ( Fujiwara, T; Inada, R; Kishimoto, H; Kondo, Y; Matsumoto, H; Mori, Y; Nagasaka, T; Toshima, T; Watanabe, A; Yagi, T, 2015) |
| "Although hyperammonemia is known as one of the adverse side effects of 5-FU, a disturbance of consciousness caused by hyperammonemia is not a usual finding." | 1.42 | [A Case of Consciousness Disturbance Caused by Hyperammonemia during a mFOLFOX6 Regimen for Metastatic Colon Cancer]. ( Egawa, C; Kagawa, Y; Kato, T; Katsura, Y; Murakami, K; Naito, A; Ohmura, Y; Okishiro, M; Takeda, Y; Takeno, A; Tamura, S, 2015) |
| "A goblet cell carcinoid of the vermiform appendix was identified as the primary tumor." | 1.35 | [Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor]. ( Flury, R; Gramann, T; Jaeger, P; Matter, L; Pfofe, D, 2009) |
| "Goblet cell carcinoids appear less frequently in the appendix than do other carcinoids." | 1.35 | Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix. ( Gulubova, MV; Hadjipetkov, P; Popharitov, A; Prangova, DK; Vlaykova, T; Yovchev, Y, 2008) |
| "Goblet cell appendiceal carcinoids represent rare tumors that exhibit histologic features of both adenocarcinomas and neuroendocrine tumors." | 1.34 | Goblet cell carcinoid tumors (adenocarcinoid) of the appendix. ( Baishnab, E; Caplin, ME; Standish, RA; Toumpanakis, C; Winslet, MC, 2007) |
| "Goblet cell carcinoid (GCC) is a rare malignant tumor with distinct histological and clinical features." | 1.33 | Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience. ( Abraham, SC; Drelichman, E; Pham, TH; Wolff, B, 2006) |
| "Gastrointestinal carcinoid tumors are often associated with other tumors, particularly colon adenocarcinomas; but the association between carcinoid tumors and hereditary nonpolyposis colorectal cancer (HNPCC) syndrome has not yet been explored." | 1.32 | An appendix carcinoid tumor in a patient with hereditary nonpolyposis colorectal cancer. ( Ducreux, M; Duvillard, P; Elias, D; Grandjouan, S; Miquel, C; Praz, F; Sabourin, JC; Viguier, J, 2004) |
| "Ovarian metastasis is frequent." | 1.31 | Adenocarcinoid of the appendix vermiformis: complete and persistent remission after chemotherapy (folfox) of a metastatic case. ( Blanchot, J; Boucher, E; Corbinais, S; Garin, L; Le Guilcher, P; Raoul, JL, 2002) |
| "The outcome of patients with mucinous appendiceal neoplasms with peritoneal surface dissemination has changed as a result of a better understanding of the clinical and pathologic features of this disease." | 1.31 | Second-look surgery in patients with peritoneal dissemination from appendiceal malignancy: analysis of prognostic factors in 98 patients. ( Esquivel, J; Sugarbaker, PH, 2001) |
| "The role in colorectal cancer is less clear, although there are some reports that suggest a benefit." | 1.30 | Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer. ( Clingan, P; Horsell, KW; King, DW; Merten, S; Morris, DL, 1999) |
| "Peritoneal carcinomatosis is a treatable condition in selected patients with a possibility for long-term disease-free survival." | 1.29 | Prognostic features for peritoneal carcinomatosis in colorectal and appendiceal cancer patients when treated by cytoreductive surgery and intraperitoneal chemotherapy. ( Chang, D; Koslowe, P; Sugarbaker, PH, 1996) |
| "Peritoneal carcinomatosis has been regarded as a uniformly lethal clinical entity with no specific plan for management." | 1.29 | Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy. ( Sugarbaker, PH, 1996) |
| "With recurrence, true metastatic disease was observed in 3 patients and a distinctly higher grade of intraperitoneal tumour in another patient." | 1.29 | Patterns of failure following treatment of pseudomyxoma peritonei of appendiceal origin. ( Sugarbaker, PH; Zoetmulder, FA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (7.79) | 18.7374 |
| 1990's | 14 (18.18) | 18.2507 |
| 2000's | 28 (36.36) | 29.6817 |
| 2010's | 23 (29.87) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, JP | 1 |
| Yousef, AM | 1 |
| Zeineddine, FA | 1 |
| Zeineddine, MA | 1 |
| Tidwell, RS | 1 |
| Beaty, KA | 1 |
| Scofield, LC | 1 |
| Rafeeq, S | 2 |
| Hornstein, N | 1 |
| Lano, E | 1 |
| Eng, C | 2 |
| Matamoros, A | 1 |
| Foo, WC | 1 |
| Uppal, A | 1 |
| Scally, C | 1 |
| Mansfield, P | 1 |
| Taggart, M | 1 |
| Raghav, KP | 1 |
| Overman, MJ | 2 |
| Fournier, K | 1 |
| Nakajima, Y | 1 |
| Kajiwara, A | 1 |
| Sakaki, M | 1 |
| Otoyama, Y | 1 |
| Nishihara, S | 1 |
| Suzuki, N | 1 |
| Usami, T | 1 |
| Nakatani, S | 1 |
| Wang, T | 1 |
| Yoshida, H | 1 |
| Alhadid, D | 1 |
| AlShammari, A | 1 |
| Almana, H | 1 |
| Aburahmah, M | 1 |
| Kolla, BC | 1 |
| Petersen, A | 1 |
| Chengappa, M | 1 |
| Gummadi, T | 1 |
| Ganesan, C | 1 |
| Gaertner, WB | 1 |
| Blaes, A | 1 |
| Ueno, A | 1 |
| Yokota, M | 1 |
| Terada, K | 1 |
| Hashida, K | 1 |
| Nagahisa, Y | 1 |
| Yamaguchi, K | 1 |
| Okabe, M | 1 |
| Kawamoto, K | 1 |
| Sugarbaker, PH | 20 |
| Barrak, D | 1 |
| Desale, S | 1 |
| Yoon, JJ | 1 |
| Dugan, MM | 1 |
| Kodavanti, PP | 1 |
| Sampah, ME | 1 |
| Das, S | 1 |
| Shi, C | 1 |
| Du, L | 1 |
| Idrees, K | 1 |
| Berlin, J | 1 |
| Turner, KM | 1 |
| Hanna, NN | 1 |
| Zhu, Y | 1 |
| Jain, A | 1 |
| Kesmodel, SB | 1 |
| Switzer, RA | 1 |
| Taylor, LM | 1 |
| Richard Alexander, H | 1 |
| Okamura, T | 1 |
| Kawachi, Y | 1 |
| Nikkuni, K | 1 |
| Nishimura, A | 1 |
| Makino, S | 1 |
| Kawahara, M | 1 |
| Kitami, C | 1 |
| Hashimoto, Y | 1 |
| Miyamoto, S | 1 |
| Tejani, MA | 1 |
| ter Veer, A | 1 |
| Milne, D | 1 |
| Ottesen, R | 1 |
| Bekaii-Saab, T | 1 |
| Benson, AB | 1 |
| Schrag, D | 1 |
| Shibata, S | 1 |
| Skibber, J | 1 |
| Weiser, M | 1 |
| Wilkinson, N | 1 |
| Cohen, SJ | 1 |
| Choe, JH | 1 |
| Fournier, KF | 1 |
| Royal, RE | 1 |
| Ohinata, A | 1 |
| Beaty, K | 1 |
| Phillips, JK | 1 |
| Wolff, RA | 1 |
| Mansfield, PF | 1 |
| Milovanov, V | 1 |
| Sardi, A | 1 |
| Ledakis, P | 1 |
| Aydin, N | 1 |
| Nieroda, C | 1 |
| Sittig, M | 1 |
| Nunez, M | 1 |
| Gushchin, V | 2 |
| Matsumoto, H | 1 |
| Inada, R | 1 |
| Nagasaka, T | 1 |
| Watanabe, A | 1 |
| Yagi, T | 1 |
| Toshima, T | 1 |
| Mori, Y | 1 |
| Kondo, Y | 1 |
| Kishimoto, H | 1 |
| Fujiwara, T | 1 |
| Lam, JY | 1 |
| McConnell, YJ | 1 |
| Rivard, JD | 1 |
| Temple, WJ | 1 |
| Mack, LA | 1 |
| Amano, K | 1 |
| Nakata, K | 1 |
| Tsujie, M | 1 |
| Sasamatsu, S | 1 |
| Nishi, H | 1 |
| Hiraki, Y | 1 |
| Shimizu, K | 1 |
| Ebihara, T | 1 |
| Kato, F | 1 |
| Hoshino, H | 1 |
| Mikami, J | 1 |
| Usui, A | 1 |
| Yamamoto, T | 1 |
| Ikeda, N | 1 |
| Kimura, Y | 1 |
| Kagawa, Y | 1 |
| Kato, T | 1 |
| Naito, A | 1 |
| Murakami, K | 1 |
| Katsura, Y | 1 |
| Ohmura, Y | 1 |
| Okishiro, M | 1 |
| Takeno, A | 1 |
| Egawa, C | 1 |
| Takeda, Y | 1 |
| Tamura, S | 1 |
| Kalpande, S | 1 |
| Pandya, J | 1 |
| Sharma, T | 1 |
| Tonooka, T | 1 |
| Takiguchi, N | 1 |
| Yamamoto, H | 1 |
| Nabeya, Y | 1 |
| Ikeda, A | 1 |
| Kainuma, O | 1 |
| Soda, H | 1 |
| Imanishi, S | 1 |
| Arimitsu, H | 1 |
| Kobayashi, R | 1 |
| Chibana, T | 1 |
| Ishige, F | 1 |
| Nagata, M | 1 |
| Woei Chung, L | 1 |
| Liao, YM | 1 |
| Hsieh, CY | 1 |
| Lin, CY | 1 |
| To, AC | 1 |
| Looi, KL | 1 |
| Damianovich, D | 1 |
| Taylor, GB | 1 |
| Sidebotham, D | 1 |
| White, HD | 1 |
| Chen, CF | 1 |
| Huang, CJ | 1 |
| Kang, WY | 1 |
| Hsieh, JS | 1 |
| Schomas, DA | 1 |
| Miller, RC | 1 |
| Donohue, JH | 1 |
| Gill, S | 1 |
| Thurmes, PJ | 1 |
| Haddock, MG | 1 |
| Quevedo, JF | 1 |
| Gunderson, LL | 1 |
| Sideris, L | 2 |
| Mitchell, A | 1 |
| Drolet, P | 1 |
| Leblanc, G | 1 |
| Leclerc, YE | 1 |
| Dubé, P | 1 |
| Sun, WL | 1 |
| Hutarew, G | 1 |
| Gradl, J | 1 |
| Gratzl, M | 1 |
| Denz, H | 1 |
| Fiegl, M | 1 |
| Gramann, T | 1 |
| Matter, L | 1 |
| Pfofe, D | 1 |
| Flury, R | 1 |
| Jaeger, P | 1 |
| Mastoraki, A | 1 |
| Papanikolaou, IS | 1 |
| Kanakis, D | 1 |
| Safioleas, P | 1 |
| Sakorafas, G | 1 |
| Safioleas, M | 1 |
| Bijelic, L | 2 |
| Chang, D | 5 |
| Yoo, D | 1 |
| Van der Speeten, K | 2 |
| Stuart, OA | 2 |
| Mahteme, H | 2 |
| Tagami, K | 1 |
| Tanda, S | 1 |
| Nomura, R | 1 |
| Saito, A | 1 |
| Takahashi, H | 1 |
| Tokumura, H | 1 |
| Maekawa, H | 1 |
| Matsumoto, F | 1 |
| Fajardo, AD | 1 |
| Tan, B | 1 |
| Reddy, R | 1 |
| Fleshman, J | 1 |
| Liang, JW | 1 |
| Wang, Z | 1 |
| Zhou, ZX | 1 |
| Zhang, XM | 1 |
| Hu, JJ | 1 |
| Zhao, P | 1 |
| Klaver, YL | 1 |
| Chua, TC | 1 |
| Verwaal, VJ | 2 |
| de Hingh, IH | 1 |
| Morris, DL | 3 |
| Rassu, PC | 1 |
| Cassinelli, G | 1 |
| Ronzitti, F | 1 |
| Bronzino, P | 1 |
| Stanizzi, T | 1 |
| Casaccia, M | 1 |
| Garin, L | 1 |
| Corbinais, S | 1 |
| Boucher, E | 1 |
| Blanchot, J | 1 |
| Le Guilcher, P | 1 |
| Raoul, JL | 1 |
| Mohamed, F | 1 |
| van Tinteren, H | 1 |
| Ruth, SV | 1 |
| Zoetmulder, FA | 2 |
| Levitz, JS | 1 |
| Lichtman, SM | 1 |
| Brun, EA | 1 |
| Miquel, C | 1 |
| Sabourin, JC | 2 |
| Elias, D | 2 |
| Grandjouan, S | 1 |
| Viguier, J | 1 |
| Ducreux, M | 1 |
| Duvillard, P | 1 |
| Praz, F | 1 |
| González-Moreno, S | 1 |
| Brun, E | 1 |
| Liberale, G | 1 |
| Lasser, P | 1 |
| Malka, D | 1 |
| Pocard, M | 1 |
| Pham, TH | 1 |
| Wolff, B | 1 |
| Abraham, SC | 1 |
| Drelichman, E | 1 |
| Alderman, R | 1 |
| Edwards, G | 1 |
| Marquardt, CE | 1 |
| Esquivel, J | 2 |
| Ceelen, WP | 1 |
| Yan, TD | 2 |
| Links, M | 1 |
| Xu, ZY | 1 |
| Kam, PC | 1 |
| Glenn, D | 1 |
| Toumpanakis, C | 1 |
| Standish, RA | 1 |
| Baishnab, E | 1 |
| Winslet, MC | 1 |
| Caplin, ME | 1 |
| Ishibashi, K | 1 |
| Sobajima, J | 1 |
| Okada, N | 1 |
| Ishizuka, N | 1 |
| Yokoyama, M | 1 |
| Mitsuhashi, T | 1 |
| Miyazaki, T | 1 |
| Nakada, H | 1 |
| Gonda, T | 1 |
| Ishida, H | 1 |
| Gulubova, MV | 1 |
| Yovchev, Y | 1 |
| Vlaykova, T | 1 |
| Hadjipetkov, P | 1 |
| Prangova, DK | 1 |
| Popharitov, A | 1 |
| Borchard, F | 1 |
| Moertel, CG | 2 |
| Hsu, KL | 1 |
| Wang, KS | 1 |
| Chen, L | 1 |
| Chou, FF | 1 |
| Fernandez-Trigo, V | 1 |
| Shamsa, F | 1 |
| Vidal-Jové, J | 1 |
| Kern, DH | 1 |
| Jablonski, KA | 1 |
| Okabe, T | 1 |
| Kumagai, N | 1 |
| Serizawa, H | 1 |
| Iwabuchi, N | 1 |
| Watanabe, N | 1 |
| Hamada, Y | 1 |
| Tsuchimoto, K | 1 |
| Yamada, Y | 1 |
| Morinaga, S | 1 |
| Ishii, H | 1 |
| Koslowe, P | 1 |
| Proulx, GM | 1 |
| Willett, CG | 1 |
| Daley, W | 1 |
| Shellito, PC | 1 |
| Hosch, WP | 1 |
| Rudi, J | 1 |
| Stremmel, W | 1 |
| Horsell, KW | 1 |
| Merten, S | 1 |
| Clingan, P | 1 |
| King, DW | 1 |
| Sasaki, A | 1 |
| Terashima, M | 1 |
| Okamoto, K | 1 |
| Ikeda, K | 1 |
| Takagane, A | 1 |
| Takiyama, I | 1 |
| Shimada, Y | 1 |
| Yamamoto, M | 1 |
| Nakajima, J | 1 |
| Sasaki, N | 1 |
| Saito, K | 1 |
| Swiatkowska-Freund, M | 1 |
| Preis, K | 1 |
| Emerich, J | 1 |
| Hata, K | 1 |
| Tanaka, N | 1 |
| Nomura, Y | 1 |
| Wada, I | 1 |
| Nagawa, H | 1 |
| Eckert, M | 1 |
| Gerassimidis, T | 1 |
| Schultess, F | 1 |
| Hammann, J | 1 |
| Beck, I | 1 |
| Ridolfi, R | 1 |
| Amaducci, L | 1 |
| Derni, S | 1 |
| Fabbri, L | 1 |
| Innocenti, MP | 1 |
| Vignutelli, P | 1 |
| Landy, D | 1 |
| Jaffe, G | 1 |
| Pascal, R | 1 |
| Chen, KT | 1 |
| Limber, GK | 1 |
| King, RE | 1 |
| Silverberg, SG | 1 |
| Reitemeier, RJ | 1 |
| Hahn, RG | 1 |
| Davis, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)[NCT05913674] | Phase 2 | 25 participants (Anticipated) | Interventional | 2023-07-31 | Not yet recruiting | ||
| Phase I Trial of Intraperitoneal Oxaliplatin in Combination With Intravenous FOLFIRI (5-fluorouracil, Leucovorin and Irinotecan) for Peritoneal Carcinomatosis From Colorectal and Appendiceal Cancer[NCT02833753] | Phase 1 | 14 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for fluorouracil and Appendiceal Cancer
| Article | Year |
|---|---|
Missed Gastric Cancer Metastasis to the Appendix: Case Report and Literature Review.
Topics: Adenocarcinoma; Anastomosis, Roux-en-Y; Antineoplastic Combined Chemotherapy Protocols; Appendiceal | 2020 |
Appendiceal tumors with glandular and neuroendocrine features exhibiting peritoneal metastases - Critical evaluation of outcome following cytoreductive surgery with perioperative chemotherapy.
Topics: Adenocarcinoma; Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Proto | 2021 |
[A case of mucinous cystadenocarcinoma of the appendix with abdominal wall abscess successfully treated by percutaneous drainage and systemic chemotherapy-a case report].
Topics: Abdominal Abscess; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Biop | 2011 |
[Primary adenocarcinoma of the appendix. Case report and review of the literature].
Topics: Adenocarcinoma; Adult; Appendectomy; Appendiceal Neoplasms; Appendicitis; Cecal Neoplasms; Chemother | 2002 |
New standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome?
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combined Modality Therapy; Fl | 2006 |
Use of hyperthermic intraperitoneal chemotherapy (HIPEC) in management of peritoneal carcinomatosis from colorectal origin.
Topics: Antineoplastic Agents; Appendiceal Neoplasms; Carcinoma; Colorectal Neoplasms; Combined Modality The | 2005 |
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C | 1982 |
Treatment of the carcinoid tumor and the malignant carcinoid syndrome.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Ap | 1983 |
Early appendiceal adenocarcinoma. A review of the literature with special reference to optimal surgical procedures.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Appendiceal Neoplasms; Fluorouracil; Humans; Japan; | 2002 |
6 trials available for fluorouracil and Appendiceal Cancer
| Article | Year |
|---|---|
Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma: A Randomized Crossover Trial.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Appendiceal Neoplasms; Colorectal | 2023 |
Systemic therapy for advanced appendiceal adenocarcinoma: an analysis from the NCCN Oncology Outcomes Database for colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; | 2014 |
Secondary cytoreductive surgery and peri-operative intraperitoneal chemotherapy for peritoneal recurrence of colorectal and appendiceal peritoneal carcinomatosis following prior primary cytoreduction.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Chemoth | 2013 |
Toxicity of cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Carcinoma; Cecum | 2004 |
Cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei from appendiceal mucinous neoplasms.
Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas | 2006 |
Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Appendicea | 1995 |
62 other studies available for fluorouracil and Appendiceal Cancer
| Article | Year |
|---|---|
[Primary appendiceal signet ring cell carcinoma:a case report].
Topics: Appendiceal Neoplasms; Carcinoma, Signet Ring Cell; Colorectal Neoplasms; Female; Fluorouracil; Huma | 2019 |
Impact of adjuvant chemotherapy on outcomes in appendiceal cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2020 |
[Appendiceal Goblet Cell Carcinoid Successfully Treated with Bevacizumab plus mFOLFOX6 Regimen-A Case Report].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Appendix; Bevacizumab; | 2020 |
Peritoneal carcinomatosis of unknown primary site, a study of 25 patients over 30 years.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; | 2020 |
Adenocarcinoma Ex-Goblet Cell: a Retrospective Experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Camptothecin; Carcinoid Tumor | 2019 |
Assessment of neoadjuvant chemotherapy on operative parameters and outcome in patients with peritoneal dissemination from high-grade appendiceal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother | 2013 |
[A case of hyperammonemic encephalopathy related to 5-FU in an aged patient with recurrent colon cancer treated with FOLFIRI therapy].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Brain Dise | 2013 |
[Bevacizumab-induced reversible posterior leukoencephalopathy syndrome in a patient with metastatic colorectal cancer].
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Anticonvulsants; Antihypertensive Agents; A | 2014 |
Improved Survival with Anti-VEGF Therapy in the Treatment of Unresectable Appendiceal Epithelial Neoplasms.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N | 2015 |
Systemic chemotherapy (SC) before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) in patients with peritoneal mucinous carcinomatosis of appendiceal origin (PMCA).
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Ch | 2015 |
[A case of appendix cancer treated as cancer of unknown primary origin].
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combi | 2015 |
Hyperthermic intraperitoneal chemotherapy + early postoperative intraperitoneal chemotherapy versus hyperthermic intraperitoneal chemotherapy alone: assessment of survival outcomes for colorectal and high-grade appendiceal peritoneal carcinomatosis.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2015 |
[A Case of Disseminated Carcinomatosis of the Bone Marrow with Disseminated Intravascular Coagulation Caused by Cecal Cancer Successfully Treated with mFOLFOX6].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Bone Marrow Neoplasms; | 2015 |
[A Case of Consciousness Disturbance Caused by Hyperammonemia during a mFOLFOX6 Regimen for Metastatic Colon Cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colectomy; Consciousness; Fem | 2015 |
Adenocarcinoma mimicking appendicular lump: a diagnostic dilemma-a case report.
Topics: Abdominal Abscess; Adenocarcinoma; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Appe | 2016 |
Management of an inguinal hernia in patients with pseudomyxoma peritonei.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N | 2017 |
[A Case of Mucinous Adenocarcinoma of the Appendix with Peritoneal Dissemination Diagnosed by Laparoscopic Abdominal Exploration and Appendectomy].
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal | 2016 |
Oxaliplatin-induced long QT syndrome in a patient with appendiceal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Female | 2009 |
A case of cardiogenic shock caused by capecitabine treatment.
Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Appendiceal Neoplasms; Biomarkers; Biopsy | 2008 |
Experience with adjuvant chemotherapy for pseudomyxoma peritonei secondary to mucinous adenocarcinoma of the appendix with oxaliplatin/fluorouracil/leucovorin (FOLFOX4).
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Che | 2008 |
Intraperitoneal treatment for peritoneal mucinous carcinomatosis of appendiceal origin after operative management: long-term follow-up of the Mayo Clinic experience.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Analysis of Variance; Appendectomy; Append | 2009 |
Surgical cytoreduction and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from the appendix.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Camptothecin; C | 2009 |
Successful antiangiogenic combination therapy for pseudomyxoma peritonei with bevacizumab and capecitabine.
Topics: Adenoma, Villous; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized | 2009 |
[Metastazation into the seminal vesicles due to primary goblet cell carcinoid of the vermiform appendix. An unusual diagnostic procedure of a seminal vesicle tumor].
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Appendix; Bioma | 2009 |
A case of signet ring carcinoma of the appendix: dilemmas in differential diagnosis and management.
Topics: Abdominal Pain; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Appendiceal Neoplasms; | 2010 |
Neoadjuvant FOLFOX chemotherapy in 34 consecutive patients with mucinous peritoneal carcinomatosis of appendiceal origin.
Topics: Adenocarcinoma, Mucinous; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Com | 2010 |
Changes induced by surgical and clinical factors in the pharmacology of intraperitoneal mitomycin C in 145 patients with peritoneal carcinomatosis.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Ap | 2011 |
Pharmacology of perioperative 5-fluorouracil.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Appendiceal Neoplasms; Female; Fluorouracil; Humans; I | 2010 |
Delayed repeated intraperitoneal chemotherapy after cytoreductive surgery for colorectal and appendiceal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colorectal Neopl | 2012 |
[Clinicopathological features and prognosis of primary appendiceal adenocarcinoma].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 2012 |
Adenocarcinoid of the appendix vermiformis: complete and persistent remission after chemotherapy (folfox) of a metastatic case.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Female; Fluor | 2002 |
Third look surgery and beyond for appendiceal malignancy with peritoneal dissemination.
Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas | 2003 |
Unusual abdominal tumors, case 1. Pseudomyxoma peritonei: response to capecitabine.
Topics: Abdominal Neoplasms; Adenocarcinoma, Mucinous; Appendiceal Neoplasms; Capecitabine; Deoxycytidine; F | 2004 |
Re: Verwaal VJ, van Tinteren H, Ruth SV, et al.: Toxicity of cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy. J Surg Oncol 2004; 85:61-67.
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Color | 2004 |
An appendix carcinoid tumor in a patient with hereditary nonpolyposis colorectal cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Appendiceal Neoplasms; Carcinoid Tumor; Chemotherapy, Adjuva | 2004 |
Lymph node metastasis in epithelial malignancies of the appendix with peritoneal dissemination does not reduce survival in patients treated by cytoreductive surgery and perioperative intraperitoneal chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combine | 2005 |
Inguinal canal as an anatomic sanctuary site of relapse in peritoneal carcinomatosis previously treated with intraperitoneal chemotherapy.
Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas | 2005 |
Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Ca | 2006 |
Prospective morbidity and mortality assessment of cytoreductive surgery plus perioperative intraperitoneal chemotherapy to treat peritoneal dissemination of appendiceal mucinous malignancy.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N | 2006 |
Goblet cell carcinoid tumors (adenocarcinoid) of the appendix.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Biomarke | 2007 |
Critical analysis of treatment failure after complete cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal dissemination from appendiceal mucinous neoplasms.
Topics: Adenocarcinoma, Mucinous; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Appen | 2007 |
[A case of pseudomyxoma peritonei successfully treated with multidisciplinary treatment including modified FOLFOX6 regimen].
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colonoscopy; Fluorouracil; Hu | 2007 |
Application of light microscopical and ultrastructural immunohistochemistry in the study of goblet cell carcinoid in the appendix.
Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Carcinoid Tumor; Fluorouracil | 2008 |
Acute appendicitis secondary to metastatic nasopharyngeal carcinoma.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; | 1995 |
Prognostic implications of chemoresistance-sensitivity assays for colorectal and appendiceal cancer.
Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Cell Survival; Colorectal Neoplasms; Dose | 1995 |
[A case of carcinomatous peritonitis for which combination therapy of 5-FU, leucovorin and cisplatin was effective].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Fl | 1996 |
Prognostic features for peritoneal carcinomatosis in colorectal and appendiceal cancer patients when treated by cytoreductive surgery and intraperitoneal chemotherapy.
Topics: Appendiceal Neoplasms; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans | 1996 |
Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Colonic Neoplasms; Female; Fluorouracil; | 1996 |
Patterns of failure following treatment of pseudomyxoma peritonei of appendiceal origin.
Topics: Abdomen; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, | 1996 |
Appendiceal carcinoma: patterns of failure following surgery and implications for adjuvant therapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Appendiceal Neoplas | 1997 |
Therapy of pseudomyxoma peritonei of appendiceal origin--surgical resection and intraperitoneal chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Chemotherapy, Ad | 1999 |
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer.
Topics: Abscess; Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; | 1999 |
[Intraperitoneal administration of a combined CDDP, 5-FU and MMC therapy for pseudomyxoma peritonei].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendiceal Neoplasms; Cisplati | 1999 |
[Appendiceal mucinous carcinoma].
Topics: Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplas | 2000 |
Second-look surgery in patients with peritoneal dissemination from appendiceal malignancy: analysis of prognostic factors in 98 patients.
Topics: Adenocarcinoma, Mucinous; Appendiceal Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; | 2001 |
[The primary appendix carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Appendiceal Neoplasms; Colostomy; Cyclophosphamide; Female; Fluorouraci | 1978 |
Chemotherapy with 5-fluorouracil and streptozotocin in carcinoid tumors of gastrointestinal origin: experiences with 13 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Carcinoid Tumor; | 1991 |
Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colonic Neoplasm | 1990 |
Appendiceal adenocarcinoid with ovarian metastasis.
Topics: Adenocarcinoma; Adult; Appendiceal Neoplasms; Female; Fluorouracil; Humans; Ovarian Neoplasms; Strep | 1990 |
Pseudomyxoma peritonaei: a report of ten cases.
Topics: Adenocarcinoma; Adult; Aged; Appendectomy; Appendiceal Neoplasms; Castration; Cystadenoma; Female; F | 1973 |
Combination chemotherapy in gastrointestinal cancer.
Topics: Adenocarcinoma; Adult; Alopecia; Appendiceal Neoplasms; Diarrhea; Drug Eruptions; Fluorouracil; Gall | 1970 |
Pseudomyxoma peritonei and the appendix.
Topics: Adult; Appendiceal Neoplasms; Cystadenoma; Fluorouracil; Humans; Male; Mucocele; Omentum; Peritoneal | 1970 |