fluorouracil has been researched along with Aphakia, Postcataract in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Aphakia, Postcataract: Absence of the crystalline lens resulting from cataract extraction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the association between after-cataract and secondary glaucoma after lensectomy and 5-fluorouracil treatment in an experimental infant rabbit model." | 3.70 | After-cataract and secondary glaucoma in the aphakic infant rabbit. ( Holmén, JB; Kugelberg, U; Lundgren, B; Lundvall, A; Zetterström, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kirwan, C | 1 |
| O'Keefe, M | 1 |
| Lanigan, B | 1 |
| Mahmood, U | 1 |
| Chew, J | 1 |
| Werner, L | 1 |
| Stevens, S | 1 |
| Hunter, B | 1 |
| Mamalis, N | 1 |
| Kugelberg, U | 1 |
| Lundvall, A | 1 |
| Lundgren, B | 1 |
| Holmén, JB | 1 |
| Zetterström, C | 1 |
3 other studies available for fluorouracil and Aphakia, Postcataract
| Article | Year |
|---|---|
Ahmed valve drainage implant surgery in the management of paediatric aphakic glaucoma.
Topics: Adolescent; Antihypertensive Agents; Aphakia, Postcataract; Child; Child, Preschool; Female; Fluorou | 2005 |
Evaluation of the effects of hydrodissection with antimitotics using a rabbit model of Soemmering's ring formation.
Topics: Acetates; Animals; Antibiotics, Antineoplastic; Antimetabolites; Aphakia, Postcataract; Capsulorhexi | 2006 |
After-cataract and secondary glaucoma in the aphakic infant rabbit.
Topics: Animals; Animals, Newborn; Anterior Chamber; Aphakia, Postcataract; Cataract; Fluorouracil; Glaucoma | 2000 |