fluorouracil has been researched along with Aortic Dissection in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 77-year-old woman treated with capecitabine for late recurrence of breast cancer developed life-threatening toxicity shortly after receiving the second cycle of therapy." | 7.76 | Case report of acute aortic dissection during treatment with capecitabine for a late recurrence of breast cancer. ( Bozzarelli, S; Carnaghi, C; Colombo, P; De Vincenzo, F; Giorgetti, PL; Rimassa, L; Santoro, A; Sclafani, F, 2010) |
| "A 77-year-old woman treated with capecitabine for late recurrence of breast cancer developed life-threatening toxicity shortly after receiving the second cycle of therapy." | 3.76 | Case report of acute aortic dissection during treatment with capecitabine for a late recurrence of breast cancer. ( Bozzarelli, S; Carnaghi, C; Colombo, P; De Vincenzo, F; Giorgetti, PL; Rimassa, L; Santoro, A; Sclafani, F, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Serrano, C | 1 |
| Suárez, C | 1 |
| Andreu, J | 1 |
| Carles, J | 1 |
| Sclafani, F | 1 |
| Carnaghi, C | 1 |
| Colombo, P | 1 |
| Bozzarelli, S | 1 |
| De Vincenzo, F | 1 |
| Rimassa, L | 1 |
| Giorgetti, PL | 1 |
| Santoro, A | 1 |
2 other studies available for fluorouracil and Aortic Dissection
| Article | Year |
|---|---|
Acute aortic dissection during sorafenib-containing therapy.
Topics: Aged; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Aortic Aneurysm; Aort | 2010 |
Case report of acute aortic dissection during treatment with capecitabine for a late recurrence of breast cancer.
Topics: Aged; Aortic Aneurysm, Abdominal; Aortic Dissection; Breast Neoplasms; Capecitabine; Deoxycytidine; | 2010 |