fluorouracil has been researched along with Aortic Diseases in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Aortic Diseases: Pathological processes involving any part of the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism." | 7.76 | Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010) |
| "After cisplatin / 5-fluorouracil chemotherapy for nasopharyngeal carcinoma, an 18-year female patient developed aortobifemoral embolism." | 3.76 | Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma. ( Bode, U; Born, M; Fleischhack, G; Heinrich, N; Hoebert, E; Simon, A; Verrel, F, 2010) |
| "This article presents a patient affected with epidermoid carcinoma of the soft palate who developed a dilated myocardiopathy with aortic embolism and fatal left cardiac failure after treatment with cisplatin (100 mg/m2, day 1) and 5-fluorouracil (1 g/m2/day i." | 3.67 | Lethal cardiac toxicity after cisplatin and 5-fluorouracil chemotherapy. Report of a case with necropsy study. ( Almenarez, J; Blázquez, J; Diaz-Rubio, E; Fariña, J; Furió, V; Martin, M, 1989) |
| "Following recurrence of cancer of the sigmoid colon, the patient received a course of XELOX plus bevacizumab(Bmab)to treat peritoneal dissemination and lung metastases." | 1.43 | [A Case of Aortoesophageal Fistula Rupture Due to Descending Thoracic Aortic Dissection with Recurrent Colon Cancer during Chemotherapy Containing Bevacizumab]. ( Fujii, T; Funahashi, K; Kaneko, H; Kaneko, T; Katayanagi, T; Koda, T; Koike, J; Kurihara, A; Masuhara, H; Sawaguchi, Y; Shimada, H; Shiokawa, H; Suzuki, T; Ushigome, M; Watanabe, Y, 2016) |
| "Aortic pseudoaneurysm formation subsequent to concurrent chemoradiotherapy (CCRT) for esophageal cancer patient with esophageal metallic stent insertion is a rare condition." | 1.42 | Aortic pseudoaneurysm formation following concurrent chemoradiotherapy and metallic stent insertion in a patient with esophageal cancer. ( Chang, MH; Chung, CS; Hou, PY; Hsieh, CH; Huang, CC; Liu, CY; Shueng, PW; Teng, CJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, PY | 1 |
| Teng, CJ | 1 |
| Chung, CS | 1 |
| Liu, CY | 1 |
| Huang, CC | 1 |
| Chang, MH | 1 |
| Shueng, PW | 1 |
| Hsieh, CH | 1 |
| Koda, T | 1 |
| Koike, J | 1 |
| Masuhara, H | 1 |
| Kurihara, A | 1 |
| Shiokawa, H | 1 |
| Ushigome, M | 1 |
| Kaneko, T | 1 |
| Suzuki, T | 1 |
| Sawaguchi, Y | 1 |
| Katayanagi, T | 1 |
| Fujii, T | 1 |
| Watanabe, Y | 1 |
| Funahashi, K | 1 |
| Shimada, H | 1 |
| Kaneko, H | 1 |
| Heinrich, N | 1 |
| Born, M | 1 |
| Hoebert, E | 1 |
| Verrel, F | 1 |
| Simon, A | 1 |
| Bode, U | 1 |
| Fleischhack, G | 1 |
| Gabrail, NY | 1 |
| Harrison, BR | 1 |
| Sunwoo, YC | 1 |
| Martin, M | 1 |
| Diaz-Rubio, E | 1 |
| Furió, V | 1 |
| Blázquez, J | 1 |
| Almenarez, J | 1 |
| Fariña, J | 1 |
5 other studies available for fluorouracil and Aortic Diseases
| Article | Year |
|---|---|
Aortic pseudoaneurysm formation following concurrent chemoradiotherapy and metallic stent insertion in a patient with esophageal cancer.
Topics: Aneurysm, False; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aortic Diseases; Chemoradio | 2015 |
[A Case of Aortoesophageal Fistula Rupture Due to Descending Thoracic Aortic Dissection with Recurrent Colon Cancer during Chemotherapy Containing Bevacizumab].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aortic Diseases; Bevacizumab; Capecitabine; Co | 2016 |
Aortobifemoral embolism in an 18-year old patient following cisplatin and 5-fluorouracil chemotherapy for nasopharyngeal carcinoma.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aortic Diseases; Arterial O | 2010 |
Chemo-irradiation induced aortoesophageal fistula.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Aortic Diseases; Cisplatin; Combine | 1991 |
Lethal cardiac toxicity after cisplatin and 5-fluorouracil chemotherapy. Report of a case with necropsy study.
Topics: Aortic Diseases; Carcinoma, Squamous Cell; Cardiomyopathy, Dilated; Cisplatin; Embolism; Fluorouraci | 1989 |