fluorouracil has been researched along with Antiphospholipid Syndrome in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Antiphospholipid Syndrome: The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Suspected pulmonary embolism was demonstrated by CT scan." | 1.31 | [Complicated antiphospholid antibody syndrome]. ( Eifrig, B; Hegewisch-Becker, S; Hossfeld, DK; Langer, F; Marx, G; Neuber, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Langer, F | 1 |
| Eifrig, B | 1 |
| Hegewisch-Becker, S | 1 |
| Marx, G | 1 |
| Neuber, K | 1 |
| Hossfeld, DK | 1 |
1 other study available for fluorouracil and Antiphospholipid Syndrome
| Article | Year |
|---|---|
[Complicated antiphospholid antibody syndrome].
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiphospholipid Syndrome; Breast Neoplasms; Carcino | 2002 |