fluorouracil has been researched along with Anophthalmia in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There was no recurrence (in six cases) and no side-effects seen in group A at final follow-up of 18." | 1.39 | Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket. ( Bodh, SA; Goel, R; Kamal, S; Kumar, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamal, S | 1 |
| Kumar, S | 1 |
| Goel, R | 1 |
| Bodh, SA | 1 |
| Kuwagata, M | 1 |
| Takashima, H | 1 |
| Nagao, T | 1 |
2 other studies available for fluorouracil and Anophthalmia
| Article | Year |
|---|---|
Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket.
Topics: Adult; Anophthalmos; Antimetabolites; Conjunctiva; Contracture; Eye Enucleation; Eye, Artificial; Fl | 2013 |
A comparison of the in vivo and in vitro response of rat embryos to 5-fluorouracil.
Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Embryo, Mammalian; Embryonic and Fetal Developme | 1998 |