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fluorouracil and Angiosarcoma

fluorouracil has been researched along with Angiosarcoma in 11 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
" A case is presented of hemangiosarcoma of theliver and spleen treated effectively by hepatic artery ligation, splenectomy, and postoperative intraportal infusion of 5-fluorouracil, as indicated by the regression of hepatic tumors on postoperative scanning and arteriograpms."3.65Hemangiosarcoma of liver and spleen treated by hepatic artery ligation, intraportal infusion chemotherapy, and splenectomy. ( Inokuchi, K; Nagasue, N; Ogawa, Y, 1976)
"Treatment of a patient with carcinoid metastases in the liver is discussed."1.31Targeted chemoembolization of tumors with poly(2-hydroxyethyl methacrylate) particles. ( Adamyan, A; Gumargalieva, K; Guseinov, E; Horák, D; Kokov, L; Skuba, N; Tchjao, A; Titova, M; Trostenyuk, N; Tsvirkun, V; Vishnevskii, V, 2000)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tardío, JC1
Nájera, L1
Alemany, I1
Martín, T1
Castaño, A1
Pérez-Regadera, JF1
Dummer, R1
Beyeler, M1
Morcinek, J1
Burg, G1
Mano, MS1
Fraser, G1
Kerr, J1
Gray, M1
Evans, V1
Kazmi, A1
Canney, P1
Lancaster, LD1
Ewy, GA1
Britsis, FA1
Zakenfel'd, GK1
Krampe, RA1
Berzinia, VIu1
Purkalne, TS1
Horák, D1
Guseinov, E1
Vishnevskii, V1
Adamyan, A1
Kokov, L1
Tsvirkun, V1
Tchjao, A1
Titova, M1
Skuba, N1
Trostenyuk, N1
Gumargalieva, K1
Nagasue, N2
Inokuchi, K2
Kobayashi, M1
Ogawa, Y2
Iwaki, A1
Fujioka, A1
Yasui, Y1
Baba, S1
Suzuki, H1
Morioka, S1
Iida, T1
al-Sarraf, M1
Go, TS1
Kithier, K1
Vaitkevicius, VK1
Schmähl, D1

Reviews

3 reviews available for fluorouracil and Angiosarcoma

ArticleYear
[Cutaneous neoplasms].
    Praxis, 2003, Sep-03, Volume: 92, Issue:36

    Topics: Adjuvants, Immunologic; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bio

2003
Cardiac consequences of malignancy and their treatment.
    Advances in internal medicine, 1984, Volume: 30

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Heart; Heart Neo

1984
[Side-effects of cytostatic therapy with special reference to potential carcinogenic effects].
    Der Internist, 1971, Volume: 12

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bus

1971

Other Studies

8 other studies available for fluorouracil and Angiosarcoma

ArticleYear
Rectal angiosarcoma after adjuvant chemoradiotherapy for adenocarcinoma of the rectum.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-20, Volume: 27, Issue:27

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Fatal Outcome; Fluorouracil

2009
Radiation-induced angiosarcoma of the breast shows major response to docetaxel after failure of anthracycline-based chemotherapy.
    Breast (Edinburgh, Scotland), 2006, Volume: 15, Issue:1

    Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neop

2006
[Combined chemoimmunotherapy in stomach cancer and hematosarcoma].
    Voprosy onkologii, 1980, Volume: 26, Issue:5

    Topics: Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Hemangiosarcoma; Humans; Immunotherapy; N

1980
Targeted chemoembolization of tumors with poly(2-hydroxyethyl methacrylate) particles.
    Journal of biomedical materials research, 2000, Volume: 51, Issue:2

    Topics: Anticoagulants; Carcinoid Tumor; Chemoembolization, Therapeutic; Colonic Neoplasms; Dalteparin; Doxo

2000
Hepatic dearterialization for nonrespectable primary and secondary tumors of the liver.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Female; Fluorouracil; Hemangiosarcoma; H

1976
Hemangiosarcoma of liver and spleen treated by hepatic artery ligation, intraportal infusion chemotherapy, and splenectomy.
    Cancer, 1976, Volume: 38, Issue:3

    Topics: Adult; Female; Fluorouracil; Hemangiosarcoma; Hepatic Artery; Humans; Ligation; Liver Neoplasms; Spl

1976
[A case of angiosarcoma effectively treated with intra-arterial continuous infusion of anticancer agents].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1986, Volume: 96, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil;

1986
Proceedings: Primary liver cancer. A review of the clinical features, blood groups, serum enzymes, therapy, and survival of 65 cases.
    Cancer, 1974, Volume: 33, Issue:2

    Topics: ABO Blood-Group System; Adenoma, Bile Duct; Adolescent; Adult; Aged; Alanine Transaminase; Alkaline

1974