fluorouracil has been researched along with Angina, Unstable in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Angina, Unstable: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 41-year-old woman who was undergoing oral chemotherapy with capecitabine for metastatic breast cancer presented with recurrent episodes of chest pain associated with electrocardiographic signs of diffuse ST segment elevation." | 7.73 | Acute coronary syndrome induced by oral capecitabine. ( Cardinale, D; Colombo, A; Colombo, N, 2006) |
| "A 41-year-old woman who was undergoing oral chemotherapy with capecitabine for metastatic breast cancer presented with recurrent episodes of chest pain associated with electrocardiographic signs of diffuse ST segment elevation." | 3.73 | Acute coronary syndrome induced by oral capecitabine. ( Cardinale, D; Colombo, A; Colombo, N, 2006) |
| " We stress the fact that while vasospasm is a well-recognized side-effect of this class of chemotherapeutic agent, broader cardiotoxicity is commonly seen and an increased awareness of the range of toxicity is necessary if repeat toxicity is to be avoided." | 1.36 | Cardiotoxicity with 5-fluorouracil and capecitabine: more than just vasospastic angina. ( Pavlakis, N; Stewart, T; Ward, M, 2010) |
| "CASE 2: A 67-year-old male with colon cancer and liver and lung metastases was referred to our Dept." | 1.36 | [Two cases of unstable angina in patients treated with bevacizumab]. ( Okada, Y; Okura, Y; Takii, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stewart, T | 1 |
| Pavlakis, N | 1 |
| Ward, M | 1 |
| Okada, Y | 1 |
| Okura, Y | 1 |
| Takii, Y | 1 |
| Luján, J | 1 |
| García De Burgos, F | 1 |
| Jordán, A | 1 |
| García, M | 1 |
| Reyes, F | 1 |
| Espinosa, MD | 1 |
| Cardinale, D | 1 |
| Colombo, A | 1 |
| Colombo, N | 1 |
| Prunier, F | 1 |
| Monségu, J | 1 |
| Coutant, G | 1 |
| Ollivier, JP | 1 |
5 other studies available for fluorouracil and Angina, Unstable
| Article | Year |
|---|---|
Cardiotoxicity with 5-fluorouracil and capecitabine: more than just vasospastic angina.
Topics: Aged; Aged, 80 and over; Angina, Unstable; Capecitabine; Cardiotoxins; Cardiovascular Diseases; Coro | 2010 |
[Two cases of unstable angina in patients treated with bevacizumab].
Topics: Aged; Angina, Unstable; Angiogenesis Inhibitors; Angiography; Antibodies, Monoclonal; Antibodies, Mo | 2010 |
[Angina related to 5-Fluorouracil].
Topics: Adenocarcinoma; Aged; Angina, Unstable; Antimetabolites, Antineoplastic; Chest Pain; Electrocardiogr | 2002 |
Acute coronary syndrome induced by oral capecitabine.
Topics: Acute Disease; Administration, Oral; Adult; Angina, Unstable; Antimetabolites, Antineoplastic; Bone | 2006 |
[Emergency coronary angioplasty following treatment with 5-fluorouracil].
Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Antimetabolites, Antineoplastic; Coronary Di | 2000 |