fluorouracil has been researched along with Anemia, Hemolytic in 18 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 68-year-old man was treated with FAM (5-fluorouracil, doxorubicin [Adriamycin], mitomycin-C) for metastic gastric adenocarcinoma." | 3.67 | Pulmonary veno-occlusive disease associated with microangiopathic hemolytic anemia and chemotherapy of gastric adenocarcinoma. ( Kerwin, DM; Smith, FP; Tsou, E; Waldhorn, RE, 1984) |
| "Following gastrectomy for locally advanced adenocarcinomas, three patients developed microangiopathic hemolytic anemia and renal failure shortly after completing courses of adjuvant chemotherapy with mitomycin and 5-FU." | 3.66 | Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome. ( Band, PR; Bettez, P; Giroux, L; Gruber, J; Jolivet, J; Laurin, S, 1983) |
| "Final diagnosis stated a multilocular metastasising gastric cancer with infiltration of bone, peritoneum and dura and signet-cell infiltration of the bone marrow." | 1.31 | [Hemorrhagic diathesis as initial symptom of stomach carcinoma]. ( Dempke, W; Kellner, O; Schmoll, HJ; von Poblozki, A; Wolf, HH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Byon, JC | 1 |
| Padilla, SM | 1 |
| Papayannopoulou, T | 2 |
| Yürek, S | 1 |
| Riess, H | 1 |
| Kreher, S | 1 |
| Dörken, B | 1 |
| Salama, A | 1 |
| Vemula, S | 1 |
| Shi, J | 1 |
| Mali, RS | 1 |
| Ma, P | 1 |
| Liu, Y | 1 |
| Hanneman, P | 1 |
| Koehler, KR | 1 |
| Hashino, E | 1 |
| Wei, L | 1 |
| Kapur, R | 1 |
| Shaaban, H | 1 |
| Downs, E | 1 |
| Shakouri, P | 1 |
| Guron, G | 1 |
| Scott, LM | 1 |
| Priestley, GV | 1 |
| Noronha, V | 1 |
| Burtness, B | 1 |
| Murren, J | 1 |
| Duffy, TP | 1 |
| Maciá Escalante, S | 1 |
| Rodríguez Lescure, A | 1 |
| Martínez Banaclocha, N | 1 |
| Gallego Plazas, J | 1 |
| Carrato Mena, A | 1 |
| Lempert, KD | 1 |
| Karlin, DA | 1 |
| Stroehlein, JR | 1 |
| Jolivet, J | 1 |
| Giroux, L | 1 |
| Laurin, S | 1 |
| Gruber, J | 1 |
| Bettez, P | 1 |
| Band, PR | 1 |
| Waldhorn, RE | 1 |
| Tsou, E | 1 |
| Smith, FP | 1 |
| Kerwin, DM | 1 |
| Ito, S | 1 |
| Hirono, S | 1 |
| Wickramasinghe, SN | 1 |
| Gulati, SC | 1 |
| Sordillo, P | 1 |
| Kempin, S | 1 |
| Reich, L | 1 |
| Magill, GB | 1 |
| Scheiner, E | 1 |
| Clarkson, B | 1 |
| Dempke, W | 1 |
| von Poblozki, A | 1 |
| Kellner, O | 1 |
| Wolf, HH | 1 |
| Schmoll, HJ | 1 |
| Claycomb, CL | 1 |
| Berkovic, M | 1 |
| Hayano, K | 1 |
| Fukui, H | 1 |
| Otsuka, Y | 1 |
| Hattori, S | 1 |
| Fleischhacker, H | 1 |
2 reviews available for fluorouracil and Anemia, Hemolytic
| Article | Year |
|---|---|
Oxaliplatin induces a delayed immune-mediated hemolytic anemia: a case report and review of the literature.
Topics: Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; | 2005 |
The deoxyuridine suppression test: a review of its clinical and research applications.
Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deox | 1981 |
16 other studies available for fluorouracil and Anemia, Hemolytic
| Article | Year |
|---|---|
Deletion of Dicer in late erythroid cells results in impaired stress erythropoiesis in mice.
Topics: Anemia, Hemolytic; Animals; Argonaute Proteins; Colony-Forming Units Assay; DEAD-box RNA Helicases; | 2014 |
Fatal immune haemolysis due to antibodies to individual metabolites of 5-fluorouracil.
Topics: Anemia; Anemia, Hemolytic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pro | 2010 |
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53.
Topics: Anemia, Hemolytic; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Bone Marr | 2012 |
A rare case of non-immune hemolytic anemia in a patient with metastatic breast cancer treated with capecitabine.
Topics: Aged; Anemia, Hemolytic; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Capecit | 2013 |
Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.
Topics: Anemia, Hemolytic; Animals; Cell Movement; Colony-Forming Units Assay; Female; Fluorouracil; Gene De | 2003 |
[Patient with haemolytic anemia and treatment with capecitabine. Review of one case and literature].
Topics: Adult; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecita | 2006 |
Haemolysis and renal impairment syndrome in patients on 5-fluorouracil and mitomycin-C.
Topics: Aged; Anemia, Hemolytic; Fluorouracil; Humans; Kidney; Kidney Diseases; Male; Mitomycins; Stomach Ne | 1980 |
Rash, nephritis, hypertension, and haemolysis in patient on 5-fluorouracil, doxorubicin, and mitomycin-C.
Topics: Aged; Anemia, Hemolytic; Antineoplastic Agents; Doxorubicin; Drug Eruptions; Drug Therapy, Combinati | 1980 |
Microangiopathic hemolytic anemia, renal failure, and noncardiogenic pulmonary edema: a chemotherapy-induced syndrome.
Topics: Adenocarcinoma; Adult; Anemia, Hemolytic; Drug Therapy, Combination; Female; Fluorouracil; Humans; K | 1983 |
Pulmonary veno-occlusive disease associated with microangiopathic hemolytic anemia and chemotherapy of gastric adenocarcinoma.
Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin | 1984 |
[Two cases with microangiopathic hemolytic anemia caused by anti-cancer drugs who improved rapidly after administration of aspirin and dipyridamole].
Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Agents; Aspirin; Chromomycin A3; Dipyridamole; Female | 1982 |
Microangiopathic anemia observed after treatment of epidermoid carcinoma with mitomycin C and 5-fluorouracil.
Topics: Anemia, Hemolytic; Carcinoma, Squamous Cell; Drug Therapy, Combination; Erythrocytes; Female; Fluoro | 1980 |
[Hemorrhagic diathesis as initial symptom of stomach carcinoma].
Topics: Algorithms; Anemia, Hemolytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplasti | 2000 |
Microangiopathic hemolytic anemia, noncardiac pulmonary edema, and renal failure after treatment of metastatic adenocarcinoma of the colon with 5-fluorouracil and mitomycin-C: report of a case.
Topics: Adenocarcinoma; Anemia, Hemolytic; Colonic Neoplasms; Female; Fluorouracil; Humans; Kidney Failure, | 1986 |
[Three cases of renal failure associated with microangiopathic hemolytic anemia after mitomycin C therapy].
Topics: Adenocarcinoma; Aged; Anemia, Hemolytic; Breast Neoplasms; Female; Fluorouracil; Glomerulonephritis, | 1988 |
[Therapy of anemias].
Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Anemia, Sideroblastic; Azathioprine; Dacti | 1970 |