fluorouracil and Anasarca
fluorouracil has been researched along with Anasarca in 28 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" She was under treatment by fluorouracil, leucovorin, oxaliplatin, and docetaxel regimen and thrombocytopenia regimen after tumor progression, but developed unconsciousness, irritability, and headache shortly after initiation of treatment." | 8.31 | Posterior reversible encephalopathy syndrome triggered by FLOT (5-fluorouracil, oxaliplatin, docetaxel, and calcium levofolinate) chemotherapy and thrombocytopenia (docetaxel and cisplatin) chemotherapy. ( Xie, L, 2023) |
"Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 7.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
"The limiting toxicity of low dose continuous infusion 5-fluorouracil (200-300 mg/m2/day) is often palmar-plantar erythrodysesthesia (PPE)." | 7.68 | Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. ( Dahlberg, S; Fabian, CJ; Giri, S; Molina, R; Slavik, M; Stephens, R, 1990) |
"A phase II trial was initiated to analyze the activity of continuously administered pioglitazone and rofecoxib combined with low-dose chemotherapy (capecitabine or temozolomide) in patients with high-grade gliomas (glioblastoma or anaplastic glioma)." | 5.12 | Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study. ( Baumgart, U; Bogdahn, U; Hau, P; Hirschmann, B; Kunz-Schughart, L; Muhleisen, H; Reichle, A; Ruemmele, P; Steinbrecher, A; Weimann, E, 2007) |
" She was under treatment by fluorouracil, leucovorin, oxaliplatin, and docetaxel regimen and thrombocytopenia regimen after tumor progression, but developed unconsciousness, irritability, and headache shortly after initiation of treatment." | 4.31 | Posterior reversible encephalopathy syndrome triggered by FLOT (5-fluorouracil, oxaliplatin, docetaxel, and calcium levofolinate) chemotherapy and thrombocytopenia (docetaxel and cisplatin) chemotherapy. ( Xie, L, 2023) |
"Glutaryl melatonin exhibited mild anti-candidiasis and anti-inflammatory properties." | 3.96 | Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis. ( Daduang, J; Damrongrungruang, T; Mahakunakorn, P; Panpitakkul, P; Panyatip, P; Priprem, A; Puthongking, P; Sangchart, P; Somudorn, J; Uthaiwat, P, 2020) |
"The limiting toxicity of low dose continuous infusion 5-fluorouracil (200-300 mg/m2/day) is often palmar-plantar erythrodysesthesia (PPE)." | 3.68 | Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion. ( Dahlberg, S; Fabian, CJ; Giri, S; Molina, R; Slavik, M; Stephens, R, 1990) |
" Increasing ascites requiring repeated paracentesis had not responded to chemotherapy including infusion of 5-fluorouracil and vincristine into the coeliac artery." | 3.65 | Carcinoid heart disease: successful tricuspid valve replacement. ( Honey, M; Paneth, M, 1975) |
"There is concern that breast cancer patients treated with left-sided radiation therapy (XRT) and doxorubicin (DOX) may have an increased risk of cardiac toxicity." | 2.69 | Treatment-related toxicity from a randomized trial of the sequencing of doxorubicin and radiation therapy in patients treated for early stage breast cancer. ( Come, SE; Gelman, RS; Gollamudi, S; Hardenbergh, PH; Harris, JR; Hayes, DF; O'Neill, A; Recht, A; Shulman, LN; Silver, B, 1999) |
"Oral mucositis is a frequent side-effect of cancer therapy." | 1.33 | Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. ( Augusto, RF; Brito, GA; Cunha, FQ; Falcão, BA; Leitão, BT; Lima, V; Rebouças, CG; Ribeiro, RA; Souza, ML, 2005) |
"Male breast cancer is very rare, especially inflammatory breast cancer, which is an aggressive, rapidly proliferating manifestation of primary breast carcinoma." | 1.33 | Inflammatory breast cancer in a male. ( Choueiri, MB; El Saghir, NS; El-Hajj, II; Otrock, ZK; Tawil, AN, 2005) |
Research
Studies (28)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (14.29) | 18.7374 |
1990's | 5 (17.86) | 18.2507 |
2000's | 7 (25.00) | 29.6817 |
2010's | 9 (32.14) | 24.3611 |
2020's | 3 (10.71) | 2.80 |
Authors
Authors | Studies |
---|---|
Sondhi, SM | 2 |
Rani, R | 2 |
Roy, P | 1 |
Agrawal, SK | 2 |
Saxena, AK | 2 |
Singh, J | 1 |
Gupta, PP | 1 |
Vendramini-Costa, DB | 1 |
de Castro, IB | 1 |
Ruiz, AL | 1 |
Marquissolo, C | 1 |
Pilli, RA | 1 |
de Carvalho, JE | 1 |
Liu, W | 1 |
Zhou, J | 1 |
Bensdorf, K | 1 |
Zhang, H | 1 |
Liu, H | 1 |
Wang, Y | 1 |
Qian, H | 1 |
Zhang, Y | 1 |
Wellner, A | 1 |
Rubner, G | 1 |
Huang, W | 1 |
Guo, C | 1 |
Gust, R | 1 |
Suthar, SK | 1 |
Jaiswal, V | 1 |
Lohan, S | 1 |
Bansal, S | 1 |
Chaudhary, A | 1 |
Tiwari, A | 1 |
Alex, AT | 1 |
Joesph, A | 1 |
Ovais, S | 1 |
Javed, K | 1 |
Yaseen, S | 1 |
Bashir, R | 1 |
Rathore, P | 1 |
Yaseen, R | 1 |
Hameed, AD | 1 |
Samim, M | 1 |
Panda, SS | 1 |
Girgis, AS | 1 |
Thomas, SJ | 1 |
Capito, JE | 1 |
George, RF | 1 |
Salman, A | 1 |
El-Manawaty, MA | 1 |
Samir, A | 1 |
Xie, L | 1 |
Damrongrungruang, T | 1 |
Panpitakkul, P | 1 |
Somudorn, J | 1 |
Sangchart, P | 1 |
Mahakunakorn, P | 1 |
Uthaiwat, P | 1 |
Daduang, J | 1 |
Panyatip, P | 1 |
Puthongking, P | 1 |
Priprem, A | 1 |
Sellick, MJ | 1 |
Michaud, M | 1 |
Wong, S | 1 |
Candler, D | 1 |
Watanabe, SM | 1 |
Domati, F | 1 |
Bonetti, LR | 1 |
Barresi, V | 1 |
Zizzo, M | 1 |
Manenti, A | 1 |
Wei, G | 1 |
Nie, MM | 1 |
Shen, XJ | 1 |
Xue, XC | 1 |
Ma, LY | 1 |
Du, CH | 1 |
Wang, SL | 1 |
Bi, JW | 1 |
Wang, PL | 1 |
Cheng, YB | 1 |
Kuerban, G | 1 |
Lima, V | 1 |
Brito, GA | 1 |
Cunha, FQ | 1 |
Rebouças, CG | 1 |
Falcão, BA | 1 |
Augusto, RF | 1 |
Souza, ML | 1 |
Leitão, BT | 1 |
Ribeiro, RA | 1 |
Choueiri, MB | 1 |
Otrock, ZK | 1 |
Tawil, AN | 1 |
El-Hajj, II | 1 |
El Saghir, NS | 1 |
Ewens, AD | 1 |
Mihich, E | 1 |
Ehrke, MJ | 1 |
Lemperle, G | 1 |
Rullan, PP | 1 |
Gauthier-Hazan, N | 1 |
Hau, P | 1 |
Kunz-Schughart, L | 1 |
Bogdahn, U | 1 |
Baumgart, U | 1 |
Hirschmann, B | 1 |
Weimann, E | 1 |
Muhleisen, H | 1 |
Ruemmele, P | 1 |
Steinbrecher, A | 1 |
Reichle, A | 1 |
Danoff, BF | 1 |
Goodman, RL | 1 |
Glick, JH | 1 |
Haller, DG | 1 |
Pajak, TF | 1 |
Lokich, JJ | 1 |
Moore, C | 1 |
Alekseenko, AV | 1 |
Iftodiĭ, AG | 1 |
Fedoriak, SS | 1 |
Reva, VB | 1 |
Luste, AO | 1 |
Goriachev, VV | 1 |
Austin, JR | 1 |
Wong, FC | 1 |
Kim, EE | 1 |
Hardenbergh, PH | 1 |
Recht, A | 1 |
Gollamudi, S | 1 |
Come, SE | 1 |
Hayes, DF | 1 |
Shulman, LN | 1 |
O'Neill, A | 1 |
Gelman, RS | 1 |
Silver, B | 1 |
Harris, JR | 1 |
Bos, AM | 1 |
van der Graaf, WT | 1 |
Willemse, PH | 1 |
Honey, M | 1 |
Paneth, M | 1 |
Bondarenko, NM | 1 |
Desiaterik, VI | 1 |
Kryshen', VP | 1 |
Fabian, CJ | 1 |
Molina, R | 1 |
Slavik, M | 1 |
Dahlberg, S | 1 |
Giri, S | 1 |
Stephens, R | 1 |
Mörsdorf, K | 1 |
Knippertz, T | 1 |
Rausch, KD | 1 |
Domenjoz, R | 1 |
Reviews
1 review available for fluorouracil and Anasarca
Article | Year |
---|---|
Avoiding and treating dermal filler complications.
Topics: Adipose Tissue; Adrenal Cortex Hormones; Animals; Autoimmune Diseases; Biocompatible Materials; Catt | 2006 |
Trials
3 trials available for fluorouracil and Anasarca
Article | Year |
---|---|
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin | 2007 |
[Use of intra-tissue electrophoresis and electrophonophoresis in the multimodal treatment of edematous forms of pancreatitis].
Topics: Adolescent; Adult; Aged; Aminophylline; Anti-Ulcer Agents; Aprotinin; Combined Modality Therapy; Ede | 1994 |
Treatment-related toxicity from a randomized trial of the sequencing of doxorubicin and radiation therapy in patients treated for early stage breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Combined Modalit | 1999 |
Other Studies
24 other studies available for fluorouracil and Anasarca
Article | Year |
---|---|
Microwave-assisted synthesis of N-substituted cyclic imides and their evaluation for anticancer and anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Drug Eval | 2009 |
Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives.
Topics: Acridines; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Line, Tumor; | 2010 |
Effect of goniothalamin on the development of Ehrlich solid tumor in mice.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carrageenan; Cel | 2010 |
Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell S | 2011 |
Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory, anticancer agents: design, synthesis and biological screening.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Ehrlich Tumor; Carra | 2013 |
Synthesis, antiproliferative and anti-inflammatory activities of some novel 6-aryl-2-(p-(methanesulfonyl)phenyl)-4,5-dihydropyridazi-3(2H)-ones.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Line, Tumor; Cell Prolif | 2013 |
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; An | 2020 |
Posterior reversible encephalopathy syndrome triggered by FLOT (5-fluorouracil, oxaliplatin, docetaxel, and calcium levofolinate) chemotherapy and thrombocytopenia (docetaxel and cisplatin) chemotherapy.
Topics: Calcium; Cisplatin; Docetaxel; Edema; Female; Fluorouracil; Headache; Humans; Leucovorin; Middle Age | 2023 |
Glutaryl Melatonin Niosome Gel for Topical Oral Mucositis: Anti- Inflammatory and Anticandidiasis.
Topics: Administration, Topical; Anhydrides; Animals; Anti-Inflammatory Agents; Antifungal Agents; Candida a | 2020 |
Subcutaneous Draining of Lower Extremity Edema in a Patient With Advanced Cancer Relieves Scrotal Swelling and Improves Mobility.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drainage; Edema; Fluoroura | 2018 |
Radiation therapy damages external anal sphincter and perineal muscle floor.
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Arterioles; Collagen; Dilatation, Pathol | 2018 |
Experimental study on sustained-release 5-Fluorouracil implantation in canine peritoneum and para-aortic abdominalis.
Topics: Animals; Antimetabolites, Antineoplastic; Dogs; Drug Implants; Edema; Fluorouracil; Humans; Inflamma | 2014 |
The clinical characteristic differences between thrombosis-related edema and lymphedema following radiotherapy or chemoradiotherapy for patients with cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2012 |
Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters.
Topics: Abscess; Animals; Antimetabolites, Antineoplastic; Cricetinae; Disease Models, Animal; Edema; Erythe | 2005 |
Inflammatory breast cancer in a male.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Cyclophospha | 2005 |
Fluorouracil plus leucovorin induces submandibular salivary gland enlargement in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Bone Marrow Cells; Dose-Response Relationship | 2005 |
The effect of adjuvant chemotherapy on cosmesis and complications in patients with breast cancer treated by definitive irradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Combined Modality Therapy; Cy | 1983 |
Chemotherapy-associated palmar-plantar erythrodysesthesia syndrome.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; | 1984 |
Positron emission tomography in the detection of residual laryngeal carcinoma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, | 1995 |
A new conservative approach to extravasation of anthracyclines with dimethylsulfoxide and dexrazoxane.
Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; C | 2001 |
Carcinoid heart disease: successful tricuspid valve replacement.
Topics: Adult; Ascites; Carcinoid Heart Disease; Carcinoid Tumor; Cardiac Catheterization; Edema; Female; Fl | 1975 |
[The effect of 5-fluorouracil on lipid metabolism in patients with acute pancreatitis].
Topics: Acute Disease; Adult; Aged; Chromatography, Thin Layer; Edema; Fluorouracil; Humans; Lipids; Middle | 1990 |
Pyridoxine therapy for palmar-plantar erythrodysesthesia associated with continuous 5-fluorouracil infusion.
Topics: Colonic Neoplasms; Edema; Erythema; Fluorouracil; Follow-Up Studies; Foot Dermatoses; Hand Dermatose | 1990 |
Studies on the antiphlogistic activity of cytostatics.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Carrageenan; Chloramphenicol; Cyclophosphamide; | 1972 |