fluorouracil has been researched along with Anaphylactic Reaction in 18 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure." | 3.91 | Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019) |
| " Each chemotherapeutic drug has the potential to induce various adverse events in the patients receiving chemotherapy." | 2.41 | [Prevention and treatment for adverse events induced by chemotherapy]. ( Tsukuda, M, 2002) |
| "Anaphylactic shock, is rare but serious, and must be considered in the event of any severe blood pressure decrease." | 1.33 | Allergic-type reactions to oxaliplatin: retrospective analysis of 42 patients. ( André, T; De Gramont, A; Louvet, C; Maindrault-Goebel, F; Perez-Staub, N; Tournigand, C; Zeghib, N, 2005) |
| "In metastatic colorectal cancer, a combination of Leucovorin (LV) and fluorouraci (l FU) with oxaliplatin (FOLFOX) is a standard first-line regimen." | 1.33 | [FOLFOX]. ( Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Mishima, H; Miyazaki, M; Nakamori, S; Tsujinaka, T; Yasui, M, 2006) |
| "To the best of our knowledge no anaphylactic reaction secondary to folinic acid (FA) administration has ever been reported before." | 1.31 | Anaphylactic shock secondary to intravenous administration of folinic acid: a first report. ( Benchalal, M; Fingerhut, A; Fouere, S; Yahchouchy-Chouillard, E, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giuliani, A | 1 |
| Romanzi, F | 1 |
| Di Sibio, A | 1 |
| Calvisi, G | 1 |
| Lombardi, L | 1 |
| Marchese, M | 1 |
| Di Staso, M | 1 |
| Schietroma, M | 1 |
| Carlei, F | 1 |
| Romano, L | 1 |
| Zhao, Y | 1 |
| An, X | 1 |
| Xiang, XJ | 1 |
| Feng, F | 1 |
| Wang, FH | 1 |
| Wang, ZQ | 1 |
| Xu, RH | 1 |
| He, YJ | 1 |
| Li, YH | 1 |
| Chay, WY | 1 |
| Chew, L | 1 |
| Yeoh, TT | 1 |
| Tan, MH | 1 |
| Kim, MY | 1 |
| Kang, SY | 1 |
| Lee, SY | 1 |
| Yang, MS | 1 |
| Kim, MH | 1 |
| Song, WJ | 1 |
| Kim, SH | 1 |
| Kim, YJ | 1 |
| Lee, KW | 1 |
| Cho, SH | 1 |
| Min, KU | 1 |
| Lee, JS | 1 |
| Kim, JH | 1 |
| Chang, YS | 1 |
| Wang, JH | 1 |
| King, TM | 1 |
| Chang, MC | 1 |
| Hsu, CW | 1 |
| Tsukuda, M | 1 |
| Maindrault-Goebel, F | 1 |
| André, T | 1 |
| Tournigand, C | 1 |
| Louvet, C | 1 |
| Perez-Staub, N | 1 |
| Zeghib, N | 1 |
| De Gramont, A | 1 |
| Mishima, H | 1 |
| Ikenaga, M | 1 |
| Tsujinaka, T | 1 |
| Yasui, M | 1 |
| Kashiwazaki, M | 1 |
| Miyazaki, M | 1 |
| Hirao, M | 1 |
| Fujitani, K | 1 |
| Nakamori, S | 1 |
| Sagawa, T | 1 |
| Sato, Y | 1 |
| Abe, S | 1 |
| Okuda, T | 1 |
| Araki, N | 1 |
| Takahari, D | 1 |
| Okamoto, T | 1 |
| Takayama, T | 1 |
| Kato, J | 1 |
| Niitsu, Y | 1 |
| Kuntz, BM | 1 |
| Schöttler, B | 1 |
| Brüster, HT | 1 |
| Larzillière, I | 1 |
| Brandissou, S | 1 |
| Breton, P | 1 |
| Lingoungou, A | 1 |
| Gargot, D | 1 |
| Ramain, JP | 1 |
| Harnois, C | 1 |
| Biswal, BM | 1 |
| Benoit, R | 1 |
| Grobost, O | 1 |
| Chalmet, P | 1 |
| Alliot, C | 1 |
| Messouak, D | 1 |
| Beets, C | 1 |
| Rapin, JP | 1 |
| Benchalal, M | 1 |
| Yahchouchy-Chouillard, E | 1 |
| Fouere, S | 1 |
| Fingerhut, A | 1 |
| DeBeer, R | 1 |
| Kabakow, B | 1 |
| Ndiritu, CG | 1 |
| Enos, LR | 1 |
| Millá Santos, A | 1 |
| Sanchiz Medina, F | 1 |
2 reviews available for fluorouracil and Anaphylactic Reaction
| Article | Year |
|---|---|
Oxaliplatin-induced severe anaphylactic reactions in metastatic colorectal cancer: case series analysis.
Topics: Adult; Aged; Anaphylaxis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Col | 2012 |
[Prevention and treatment for adverse events induced by chemotherapy].
Topics: Anaphylaxis; Antineoplastic Agents; Brain Diseases; Cisplatin; Docetaxel; Fluorouracil; Humans; Neop | 2002 |
16 other studies available for fluorouracil and Anaphylactic Reaction
| Article | Year |
|---|---|
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si | 2019 |
[Clinical features of hypersensitivity reactions to oxaliplatin among Chinese colorectal cancer patients].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adolescent; Adult; Aged; Anaphylaxis; Anti-Allergic Agents | 2010 |
An association between transient hypokalemia and severe acute oxaliplatin-related toxicity predominantly in women.
Topics: Adult; Aged; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deglutition | 2010 |
Hypersensitivity reactions to oxaliplatin: clinical features and risk factors in Koreans.
Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Deoxycy | 2012 |
Allergic-type reactions to oxaliplatin: retrospective analysis of 42 patients.
Topics: Adult; Aged; Aged, 80 and over; Anaphylaxis; Antineoplastic Agents; Antineoplastic Combined Chemothe | 2005 |
[FOLFOX].
Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluoroura | 2006 |
[Anaphylactic reaction to oxaliplatin--a case of colon cancer].
Topics: Adenocarcinoma; Aged; Anaphylaxis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto | 2006 |
[Resuscitation necessitated by a transfusion reaction after HLA mismatched platelets substitution].
Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cyt | 1994 |
Anaphylactic reaction to oxaliplatin: a case report.
Topics: Adenocarcinoma; Anaphylaxis; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 1999 |
Anaphylaxis following continuous 5-fluorouracil infusion chemotherapy.
Topics: Anaphylaxis; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Fluorouracil; Humans; Male; | 1999 |
[Anaphylactoid shock due to folinic acid during treatment of metastatic colorectal cancer].
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anaphylaxis; Antimetabolites, Antineoplastic; Colorectal Ne | 2000 |
Severe anaphylactic reaction to oxaliplatin.
Topics: Adult; Anaphylaxis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Fluoroura | 2001 |
Anaphylactic shock secondary to intravenous administration of folinic acid: a first report.
Topics: Aged; Aged, 80 and over; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; | 2002 |
Anaphylactoid reaction. Associated with intravenous administration of 5-fluorouracil.
Topics: Anaphylaxis; Colonic Neoplasms; Fluorouracil; Humans; Male; Middle Aged | 1979 |
Adverse reactions to drugs in a veterinary hospital.
Topics: Amphotericin B; Anaphylaxis; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Chloral Hydrate; | 1977 |
Anaphylactic reaction following i.v. administration of 5-fluorouracil.
Topics: Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dox | 1986 |