fluorouracil has been researched along with Amaurosis in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe the case of a colon cancer patient who underwent adjuvant treatment with capecitabine and oxaliplatin and was admitted to the hospital with seizures and brain edema." | 3.80 | [Blindness and symmetrical neurological deficit in a patient with colon cancer receiving adjuvant chemotherapy: is it always cancer?]. ( Fennig, S; Greenberg, G; Leshem, Y; Talianski, E; Wolf, I, 2014) |
| "Primary open angle glaucoma (POAG) is one of the leading causes of avoidable blindness." | 1.34 | Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria. ( Lawan, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leshem, Y | 1 |
| Fennig, S | 1 |
| Talianski, E | 1 |
| Greenberg, G | 1 |
| Wolf, I | 1 |
| McNaught, A | 1 |
| Lawan, A | 1 |
| Chan, RC | 1 |
| Shukovsky, LJ | 1 |
| Harvey, HJ | 1 |
| MacEwen, EG | 1 |
| Hayes, AA | 1 |
| Arsac, M | 1 |
| Bonnet, G | 1 |
| Mouzon, M | 1 |
6 other studies available for fluorouracil and Amaurosis
| Article | Year |
|---|---|
[Blindness and symmetrical neurological deficit in a patient with colon cancer receiving adjuvant chemotherapy: is it always cancer?].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blindness; Brain Neoplasms; Capecitabine; Chemothera | 2014 |
Loss of vision after phacotrabeculectomy.
Topics: Antimetabolites; Blindness; Chemotherapy, Adjuvant; Conjunctival Diseases; Cysts; Diabetes Complicat | 2005 |
Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria.
Topics: Adult; Age Distribution; Aged; Antimetabolites; Blindness; Female; Fluorouracil; Glaucoma, Open-Angl | 2007 |
Effects of irradiation on the eye.
Topics: Blindness; Cataract; Eye; Eye Diseases; Fluorouracil; Humans; Nose Neoplasms; Paranasal Sinus Neopla | 1976 |
Neurotoxicosis associated with use of 5-fluorouracil in five dogs and one cat.
Topics: Animals; Ataxia; Blindness; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Fluorouracil; Male; Nerv | 1977 |
[Cancer of the body of the pancreas with hepatic metastases].
Topics: Abdomen; Blindness; Catheterization; Cholangiography; Coma; Diagnosis, Differential; Fluorouracil; H | 1968 |