fluorouracil has been researched along with Alveolitis, Fibrosing in 13 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary fibrosis is a rare complication of oxaliplatin and capecitabine/5-fluorouracil." | 4.87 | Pulmonary toxicity with oxaliplatin and capecitabine/5-Fluorouracil chemotherapy: a case report and review of the literature. ( Chan, AK; Choo, BA; Glaholm, J, 2011) |
| "To evaluate the factors associated with pulmonary fibrosis after postmastectomy electron beam irradiation of chest wall and regional lymphatics in patients with breast cancer." | 2.69 | Multivariate analysis of pulmonary fibrosis after electron beam irradiation for postmastectomy chest wall and regional lymphatics: evidence for non-dosimetric factors. ( Chen, HC; Fang, FM; Hsiung, CY; Hsu, HC; Huang, EY; Sun, LM; Wang, CJ; Wu, JM; Yeh, SA, 2000) |
| " Addition of chemotherapy with doxorubicin and cyclophosphamide significantly increased the proportion of patients with pulmonary fibrosis compared with patients treated with radiotherapy only or radiotherapy combined with cyclophosphamide, methotrexate and 5-fluorouracil." | 2.66 | Tolerance of radiotherapy combined with adjuvant chemotherapy in breast cancer. ( Hrafnkelsson, J; Nilsson, K; Söderberg, M, 1987) |
| " This rare but potentially fatal side effect has neither identified risk factors nor established treatment guideline." | 2.48 | Oxaliplatin-induced lung toxicity. Case report and review of the literature. ( Abeni, C; Bertocchi, P; Prochilo, T; Zaniboni, A, 2012) |
| "Interstitial lung disease in patients with colorectal cancer during chemotherapy combined with bevacizumab is rare." | 1.37 | Interstitial lung disease during chemotherapy combined with oxaliplatin and/or bevacizumab in advanced colorectal cancer patients. ( Furushima, K; Ishihara, T; Katou, Y; Tanai, C; Tanaka, Y; Usui, K, 2011) |
| "Two fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis are reported here." | 1.35 | Fatal pneumonitis induced by oxaliplatin. ( Arévalo Lobera, S; Azkue Gabilondo, M; Basterretxea Badiola, L; Egaña Otaño, L; Elejoste Echeberría, I; La Casta Muñoa, A; Melé Olivé, M; Sagastibeltza Mariñelarena, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arévalo Lobera, S | 1 |
| Sagastibeltza Mariñelarena, N | 1 |
| Elejoste Echeberría, I | 1 |
| Melé Olivé, M | 1 |
| Egaña Otaño, L | 1 |
| Basterretxea Badiola, L | 1 |
| La Casta Muñoa, A | 1 |
| Azkue Gabilondo, M | 1 |
| Usui, K | 1 |
| Katou, Y | 1 |
| Furushima, K | 1 |
| Tanaka, Y | 1 |
| Tanai, C | 1 |
| Ishihara, T | 1 |
| Chan, AK | 1 |
| Choo, BA | 1 |
| Glaholm, J | 1 |
| Prochilo, T | 1 |
| Abeni, C | 1 |
| Bertocchi, P | 1 |
| Zaniboni, A | 1 |
| Mundt, P | 1 |
| Mochmann, HC | 1 |
| Ebhardt, H | 1 |
| Zeitz, M | 1 |
| Duchmann, R | 1 |
| Pauschinger, M | 1 |
| Huang, EY | 1 |
| Wang, CJ | 1 |
| Chen, HC | 1 |
| Sun, LM | 1 |
| Fang, FM | 1 |
| Yeh, SA | 1 |
| Hsu, HC | 1 |
| Hsiung, CY | 1 |
| Wu, JM | 1 |
| Trisolini, R | 1 |
| Lazzari Agli, L | 1 |
| Tassinari, D | 1 |
| Rondelli, D | 1 |
| Cancellieri, A | 1 |
| Patelli, M | 1 |
| Falcone, F | 1 |
| Poletti, V | 1 |
| Fielding, JW | 2 |
| Crocker, J | 1 |
| Stockley, RA | 2 |
| Brookes, VS | 2 |
| Flubacher, P | 1 |
| Meier, V | 1 |
| Obrecht, JP | 1 |
| Hartmann, D | 1 |
| Hrafnkelsson, J | 1 |
| Nilsson, K | 1 |
| Söderberg, M | 1 |
| Tallósy, I | 1 |
| Vargha, G | 1 |
| Pölöskey, A | 1 |
| Nagy, Z | 1 |
| Kricskovits, A | 1 |
| Tucci, E | 1 |
| Verdiani, P | 1 |
| Di Carlo, S | 1 |
| Sforza, V | 1 |
2 reviews available for fluorouracil and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Pulmonary toxicity with oxaliplatin and capecitabine/5-Fluorouracil chemotherapy: a case report and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colectom | 2011 |
Oxaliplatin-induced lung toxicity. Case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Fluorouracil; Humans; Imatinib Mesylate; | 2012 |
2 trials available for fluorouracil and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Multivariate analysis of pulmonary fibrosis after electron beam irradiation for postmastectomy chest wall and regional lymphatics: evidence for non-dosimetric factors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvan | 2000 |
Tolerance of radiotherapy combined with adjuvant chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; | 1987 |
9 other studies available for fluorouracil and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Fatal pneumonitis induced by oxaliplatin.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoc | 2008 |
Interstitial lung disease during chemotherapy combined with oxaliplatin and/or bevacizumab in advanced colorectal cancer patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alveolitis, Extrinsic Allergic; Antibodies, Monoclona | 2011 |
Pulmonary fibrosis after chemotherapy with oxaliplatin and 5-fluorouracil for colorectal cancer.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Antineoplastic Combined Chemotherapy Protocols; Fluor | 2007 |
Acute lung injury associated with 5-fluorouracil and oxaliplatinum combined chemotherapy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lung; Male; Mid | 2001 |
Interstitial fibrosis in a patient treated with 5-fluorouracil and mitomycin C.
Topics: Fluorouracil; Humans; Mitomycins; Pulmonary Fibrosis | 1979 |
Interstitial lung disease in a patient treated with 5-fluorouracil and mitomycin C.
Topics: Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; Male; Middle Aged; Mitomycins; P | 1978 |
[Cytostatic pneumopathy following chemotherapy for metastasizing breast neoplasm].
Topics: Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Ethinyl Estradiol; Female; Femo | 1977 |
[Analysis of alveolitis (pneumonitis) as a complication of cytostatic (CMF) therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorour | 1987 |
Lomustine (CCNU)-induced pulmonary fibrosis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Lomustine; Male; Pulmon | 1986 |