Page last updated: 2024-10-27

fluorouracil and Alveolar Bone Atrophy

fluorouracil has been researched along with Alveolar Bone Atrophy in 7 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"To assess sodium alendronate as a local adjunctive therapy for treating experimental periodontitis in male rats treated with chemotherapy."8.31Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy. ( de Almeida, JM; Ervolino, E; Fiorin, LG; Furquim, EMA; Matheus, HR; Novaes, VCN; Oliveira, FLP; Piovezan, BR, 2023)
"The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuvant to mechanical treatment of experimental periodontitis (EP) in adult rats submitted to 5-fluorouracil (5-FU) chemotherapy."7.85Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil. ( de Almeida, JM; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Miessi, DMJ; Novaes, VCN; Theodoro, LH, 2017)
"This study aimed to assess the effect of multiple sessions of a low-level laser therapy (LLLT) adjuvant to scaling and root planing (SRP) on the treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)."7.83Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy. ( Assem, NZ; Duque, C; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Louzada, LM; Theodoro, LH, 2016)
"This study aimed to evaluate the progression and treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)."7.81Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil. ( Bomfim, SR; de Almeida, JM; Ervolino, E; Garcia, VG; Longo, M; Novaes, VC; Theodoro, LH, 2015)
"To assess sodium alendronate as a local adjunctive therapy for treating experimental periodontitis in male rats treated with chemotherapy."4.31Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy. ( de Almeida, JM; Ervolino, E; Fiorin, LG; Furquim, EMA; Matheus, HR; Novaes, VCN; Oliveira, FLP; Piovezan, BR, 2023)
"The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuvant to mechanical treatment of experimental periodontitis (EP) in adult rats submitted to 5-fluorouracil (5-FU) chemotherapy."3.85Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil. ( de Almeida, JM; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Miessi, DMJ; Novaes, VCN; Theodoro, LH, 2017)
"This study aimed to assess the effect of multiple sessions of a low-level laser therapy (LLLT) adjuvant to scaling and root planing (SRP) on the treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)."3.83Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy. ( Assem, NZ; Duque, C; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Louzada, LM; Theodoro, LH, 2016)
"This study aimed to evaluate the progression and treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)."3.81Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil. ( Bomfim, SR; de Almeida, JM; Ervolino, E; Garcia, VG; Longo, M; Novaes, VC; Theodoro, LH, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Novaes, VCN3
Ervolino, E7
Fernandes, GL1
Cunha, CP1
Theodoro, LH6
Garcia, VG5
de Almeida, JM4
Oliveira, FLP1
Matheus, HR1
Piovezan, BR1
Furquim, EMA1
Fiorin, LG1
Rocha, TED1
Gomes, NA1
Miessi, DMJ2
Nuernberg, MAA1
Rodrigues, JVS1
Cardoso, JM1
Longo, M4
Ferro-Alves, ML2
Gouveia Garcia, V1
Ferro Alves, ML1
Duque, C2
Wainwright, M1
Novaes, VC1
Bomfim, SR1
Assem, NZ1
Louzada, LM1

Other Studies

7 other studies available for fluorouracil and Alveolar Bone Atrophy

ArticleYear
Influence of the treatment with the antineoplastic agents 5-fluorouracil and cisplatin on the severity of experimental periodontitis in rats.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:3

    Topics: Alveolar Bone Loss; Animals; Antineoplastic Agents; Cisplatin; Fluorouracil; Male; Periodontitis; Ra

2022
Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy.
    Archives of oral biology, 2023, Volume: 155

    Topics: Alendronate; Alveolar Bone Loss; Animals; Dental Scaling; Fluorouracil; Male; Osteocalcin; Periodont

2023
Adjuvant effects of Saccharomyces cerevisiae in the treatment of experimental periodontitis in rats undergoing chemotherapy.
    Journal of applied oral science : revista FOB, 2023, Volume: 31

    Topics: Adjuvants, Immunologic; Alveolar Bone Loss; Animals; Dental Scaling; Fluorouracil; Periodontitis; Ra

2023
Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:10

    Topics: Alveolar Bone Loss; Animals; Anti-Infective Agents; Combined Modality Therapy; Fluorouracil; Low-Lev

2017
Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: histomorphometrical, immunohistochemical, immunological and microbiological analyses.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 25

    Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Animals; Dental Scaling; Disease Models,

2019
Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:7

    Topics: Alveolar Bone Loss; Animals; Dental Scaling; Disease Progression; Fluorouracil; Leukocytes; Male; Ne

2015
Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy.
    Journal of periodontal research, 2016, Volume: 51, Issue:5

    Topics: Alveolar Bone Loss; Animals; Bacteria; Caspase 3; Combined Modality Therapy; Dental Scaling; Dinopro

2016