fluorouracil has been researched along with Alcohol Abuse in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of cisplatin and alcohol abuse in this neurotoxic episode, can not yet completely be excluded." | 1.29 | [Acute cerebellar syndrome after treatment with 5-fluorouracil]. ( Barbieux, C; Cerf, I; de Parades, V; Patri, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wickramasinghe, SN | 1 |
| Barbieux, C | 1 |
| Patri, B | 1 |
| Cerf, I | 1 |
| de Parades, V | 1 |
| Stratigos, JD | 1 |
| Katsambas, A | 1 |
1 review available for fluorouracil and Alcohol Abuse
| Article | Year |
|---|---|
The deoxyuridine suppression test: a review of its clinical and research applications.
Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deox | 1981 |
2 other studies available for fluorouracil and Alcohol Abuse
| Article | Year |
|---|---|
[Acute cerebellar syndrome after treatment with 5-fluorouracil].
Topics: Alcoholism; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cerebellar Ata | 1996 |
Pellagra: a still existing disease.
Topics: Alcoholism; Diet; Fluorouracil; Humans; Intestinal Absorption; Isoniazid; Mercaptopurine; Nicotinic | 1977 |