fluorouracil has been researched along with African Lymphoma in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Similarly, constitutive hTERT expression inhibited wild-type p53-dependent apoptosis in response to mitomycin C or 5-fluorouracil in HCT116 colon carcinoma cells carrying endogenous p53." | 3.73 | hTERT antagonizes p53-induced apoptosis independently of telomerase activity. ( Latonen, L; Rahman, R; Wiman, KG, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, J | 1 |
| Qin, J | 1 |
| Zheng, Y | 1 |
| Peng, X | 1 |
| Luo, Y | 1 |
| Meng, X | 1 |
| Rahman, R | 1 |
| Latonen, L | 1 |
| Wiman, KG | 1 |
| Vrba, M | 1 |
| Adámek, R | 1 |
| Blasko, M | 1 |
| Brezina, V | 1 |
| Chrz, R | 1 |
| Goetz, P | 1 |
| Michalová, K | 1 |
| Musilová, J | 1 |
| Novotná, B | 1 |
| Pogosianz, HE | 1 |
| Raposa, T | 1 |
| Siracký, J | 1 |
| Sokova, OI | 2 |
| Thust, R | 1 |
| Ujházy, V | 1 |
| Volgareva, GM | 2 |
| Feng, WH | 1 |
| Israel, B | 1 |
| Raab-Traub, N | 1 |
| Busson, P | 1 |
| Kenney, SC | 1 |
| Pogosiants, EE | 1 |
| Wheeler, RH | 1 |
| Bull, FE | 1 |
| Ruddon, RW | 1 |
| Ravina, A | 1 |
1 review available for fluorouracil and African Lymphoma
| Article | Year |
|---|---|
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactino | 1969 |
6 other studies available for fluorouracil and African Lymphoma
| Article | Year |
|---|---|
PEG10 promotes the migration of human Burkitt's lymphoma cells by up-regulating the expression of matrix metalloproteinase-2 and -9.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Burkitt Lymphoma; Cell Line, Tumor; Cel | 2012 |
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
Topics: Apoptosis; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA-Bind | 2005 |
Clastogenicity and sister chromatid exchange induction by ftorafur.
Topics: Animals; Burkitt Lymphoma; Cell Line; Chromosomes; Chromosomes, Human; Cricetinae; Crossing Over, Ge | 1981 |
Chemotherapy induces lytic EBV replication and confers ganciclovir susceptibility to EBV-positive epithelial cell tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carcinoma; Cisplatin; Dru | 2002 |
[Effect of ftorafur on the chromosomes of human normal and tumor cells in vitro].
Topics: Burkitt Lymphoma; Cells, Cultured; Chromosomes, Human; Dose-Response Relationship, Drug; Fluorouraci | 1979 |
The effect of heparin on the cytotoxicity and uptake of anti-neoplastic drugs in cultured Burkitt lymphoma cells.
Topics: Burkitt Lymphoma; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Hepari | 1974 |