fluorouracil and Adrenal Insufficiency
fluorouracil has been researched along with Adrenal Insufficiency in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
Research
Studies (6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (50.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors
Authors | Studies |
---|---|
Smolenschi, C | 1 |
Tazdait, M | 1 |
Kuhn, E | 1 |
Boige, V | 1 |
Nomura, M | 1 |
Sasano, H | 1 |
Okada, Y | 1 |
Watanabe, T | 1 |
Sakamoto, S | 1 |
Sakiyama, Y | 1 |
Sakamoto, R | 1 |
Abe, I | 1 |
Horiuchi, T | 1 |
Yanase, T | 1 |
Takayanagi, R | 1 |
Harris, LN | 1 |
Ragaz, J | 1 |
Morgan, MW | 1 |
Piro, AJ | 1 |
Wilson, RE | 1 |
Nevinny, HB | 1 |
Awe, WC | 1 |
Donaldson, SS | 1 |
Fletcher, WS | 1 |
Other Studies
6 other studies available for fluorouracil and Adrenal Insufficiency
Article | Year |
---|---|
Bilateral adrenal haematoma complicated by adrenal insufficiency in a patient treated with bevacizumab.
Topics: Adrenal Insufficiency; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neopl | 2021 |
Adrenal failure caused by a retroperitoneal malignant mesothelioma.
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Antineoplastic Combined Chemotherapy Protocols; Cisp | 2009 |
Ventricular arrhythmia and adrenal insufficiency after fluorouracil: new side effects of an old drug.
Topics: Adrenal Insufficiency; Adult; Arrhythmias, Cardiac; Breast Neoplasms; Electrocardiography; Female; F | 1993 |
Adrenal suppression after short-term corticosteroid therapy.
Topics: Adrenal Cortex; Adrenal Insufficiency; Depression, Chemical; Floxuridine; Fluorouracil; Humans; In V | 1979 |
Cyclophosphamide therapy in patients with advancing breast cancer following adrenalectomy and 5-fluorouracil.
Topics: Adrenal Insufficiency; Adrenalectomy; Adult; Aged; Alopecia; Breast Neoplasms; Cortisone; Cyclophosp | 1971 |
Increased sensitivity to 5-fluorouracil in patients with adrenal insufficiency.
Topics: Adrenal Insufficiency; Aged; Drug Hypersensitivity; Female; Fluorouracil; Humans; Middle Aged | 1966 |