Page last updated: 2024-10-27

fluorouracil and Adrenal Insufficiency

fluorouracil has been researched along with Adrenal Insufficiency in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Smolenschi, C1
Tazdait, M1
Kuhn, E1
Boige, V1
Nomura, M1
Sasano, H1
Okada, Y1
Watanabe, T1
Sakamoto, S1
Sakiyama, Y1
Sakamoto, R1
Abe, I1
Horiuchi, T1
Yanase, T1
Takayanagi, R1
Harris, LN1
Ragaz, J1
Morgan, MW1
Piro, AJ1
Wilson, RE1
Nevinny, HB1
Awe, WC1
Donaldson, SS1
Fletcher, WS1

Other Studies

6 other studies available for fluorouracil and Adrenal Insufficiency

ArticleYear
Bilateral adrenal haematoma complicated by adrenal insufficiency in a patient treated with bevacizumab.
    BMJ case reports, 2021, Feb-22, Volume: 14, Issue:2

    Topics: Adrenal Insufficiency; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neopl

2021
Adrenal failure caused by a retroperitoneal malignant mesothelioma.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:24

    Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Antineoplastic Combined Chemotherapy Protocols; Cisp

2009
Ventricular arrhythmia and adrenal insufficiency after fluorouracil: new side effects of an old drug.
    Journal of the National Cancer Institute, 1993, Feb-17, Volume: 85, Issue:4

    Topics: Adrenal Insufficiency; Adult; Arrhythmias, Cardiac; Breast Neoplasms; Electrocardiography; Female; F

1993
Adrenal suppression after short-term corticosteroid therapy.
    Lancet (London, England), 1979, Apr-28, Volume: 1, Issue:8122

    Topics: Adrenal Cortex; Adrenal Insufficiency; Depression, Chemical; Floxuridine; Fluorouracil; Humans; In V

1979
Cyclophosphamide therapy in patients with advancing breast cancer following adrenalectomy and 5-fluorouracil.
    Cancer, 1971, Volume: 27, Issue:6

    Topics: Adrenal Insufficiency; Adrenalectomy; Adult; Aged; Alopecia; Breast Neoplasms; Cortisone; Cyclophosp

1971
Increased sensitivity to 5-fluorouracil in patients with adrenal insufficiency.
    Northwest medicine, 1966, Volume: 65, Issue:1

    Topics: Adrenal Insufficiency; Aged; Drug Hypersensitivity; Female; Fluorouracil; Humans; Middle Aged

1966
chemdatabank.com