fluorouracil has been researched along with Adrenal Cortex Cancer in 9 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen patients with progressive metastatic adrenal cortical carcinoma were treated with a combination of 5-fluorouracil (5-FU), doxorubicin, and cisplatin (FAP)." | 7.68 | 5-Fluorouracil, doxorubicin, and cisplatin as treatment for adrenal cortical carcinoma. ( Brugieres, L; Droz, JP; Gicquel, C; Parmentier, C; Schlumberger, M; Travagli, JP, 1991) |
| "Five patients with metastatic adrenal cortical carcinoma were treated with a combination of 5-fluorouracil (5-FU), doxorubicin, and cisplatin." | 7.67 | 5-Fluorouracil, doxorubicin, and cisplatin regimen in adrenal cortical carcinoma. ( Bellaiche, M; Droz, JP; Ostronoff, M; Parmentier, C; Rougier, P; Schlumberger, M, 1988) |
| "No standard therapy for advanced adrenocortical carcinoma (ACC) is established by any randomized trial but a consensus conference 2003 recommended mitotane as monotherapy or combined with etoposide, doxorubicin and cisplatin or with streptozotocin as first-line systemic therapy." | 6.75 | Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma. ( Allolio, B; Fassnacht, M; Hahner, S; Johanssen, S; Kroiss, M; Quinkler, M; Ritter, C; Wortmann, S, 2010) |
| "The efficacy of mitotane in providing objective tumour responses in patients with adrenocortical carcinoma (ACC), has been recently questioned." | 6.17 | Cytotoxic chemotherapy for adrenocortical carcinoma. ( Alì, A; Angeli, A; Berruti, A; Dogliotti, L; Paccotti, P; Pia, A, 1995) |
| "Fourteen patients with progressive metastatic adrenal cortical carcinoma were treated with a combination of 5-fluorouracil (5-FU), doxorubicin, and cisplatin (FAP)." | 3.68 | 5-Fluorouracil, doxorubicin, and cisplatin as treatment for adrenal cortical carcinoma. ( Brugieres, L; Droz, JP; Gicquel, C; Parmentier, C; Schlumberger, M; Travagli, JP, 1991) |
| "Five patients with metastatic adrenal cortical carcinoma were treated with a combination of 5-fluorouracil (5-FU), doxorubicin, and cisplatin." | 3.67 | 5-Fluorouracil, doxorubicin, and cisplatin regimen in adrenal cortical carcinoma. ( Bellaiche, M; Droz, JP; Ostronoff, M; Parmentier, C; Rougier, P; Schlumberger, M, 1988) |
| "No standard therapy for advanced adrenocortical carcinoma (ACC) is established by any randomized trial but a consensus conference 2003 recommended mitotane as monotherapy or combined with etoposide, doxorubicin and cisplatin or with streptozotocin as first-line systemic therapy." | 2.75 | Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma. ( Allolio, B; Fassnacht, M; Hahner, S; Johanssen, S; Kroiss, M; Quinkler, M; Ritter, C; Wortmann, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mercier, C | 1 |
| Dupuis, C | 1 |
| Blesius, A | 1 |
| Fanciullino, R | 1 |
| Yang, CG | 1 |
| Padovani, L | 1 |
| Giacometti, S | 1 |
| Frances, N | 1 |
| Iliadis, A | 1 |
| Duffaud, F | 1 |
| Ciccolini, J | 1 |
| Wortmann, S | 1 |
| Quinkler, M | 1 |
| Ritter, C | 1 |
| Kroiss, M | 1 |
| Johanssen, S | 1 |
| Hahner, S | 1 |
| Allolio, B | 1 |
| Fassnacht, M | 1 |
| Sperone, P | 1 |
| Ferrero, A | 1 |
| Daffara, F | 1 |
| Priola, A | 1 |
| Zaggia, B | 1 |
| Volante, M | 1 |
| Santini, D | 1 |
| Vincenzi, B | 1 |
| Badalamenti, G | 1 |
| Intrivici, C | 1 |
| Del Buono, S | 1 |
| De Francia, S | 1 |
| Kalomirakis, E | 1 |
| Ratti, R | 1 |
| Angeli, A | 2 |
| Dogliotti, L | 2 |
| Papotti, M | 1 |
| Terzolo, M | 1 |
| Berruti, A | 2 |
| Pia, A | 1 |
| Paccotti, P | 1 |
| Alì, A | 1 |
| Visconti, EB | 1 |
| Peters, RW | 1 |
| Cangir, A | 1 |
| Zorn, GL | 1 |
| Fisher, S | 1 |
| Schlumberger, M | 2 |
| Brugieres, L | 1 |
| Gicquel, C | 1 |
| Travagli, JP | 1 |
| Droz, JP | 2 |
| Parmentier, C | 2 |
| Kamiyama, T | 1 |
| Une, Y | 1 |
| Satou, Y | 1 |
| Sano, F | 1 |
| Uchino, J | 1 |
| Morita, Y | 1 |
| Nojima, T | 1 |
| Katsumi, T | 1 |
| Murayama, K | 1 |
| Ostronoff, M | 1 |
| Bellaiche, M | 1 |
| Rougier, P | 1 |
1 review available for fluorouracil and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Cytotoxic chemotherapy for adrenocortical carcinoma.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols | 1995 |
3 trials available for fluorouracil and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Angiogenesis Inhibitors; Antibodies | 2010 |
Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antimetabolites, Antineoplastic; An | 2010 |
Cytotoxic chemotherapy for adrenocortical carcinoma.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols | 1995 |
6 other studies available for fluorouracil and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile.
Topics: Adrenal Cortex Neoplasms; Antimetabolites, Antineoplastic; Capecitabine; Cytidine Deaminase; Deoxycy | 2009 |
Unusual case of adrenal cortical carcinoma in a female infant.
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Cyclophosphamide; Dactinomycin; Female; Fluoroura | 1978 |
5-Fluorouracil, doxorubicin, and cisplatin as treatment for adrenal cortical carcinoma.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcino | 1991 |
[A case of non-functioning adrenocortical tumor].
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Combined Modality Therapy; Female | 1990 |
[A case of non-functioning adrenal cortical carcinoma with pulmonary and bony metastases].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Antineoplastic Agents; Bone Neoplasms; Combined Modality Th | 1989 |
5-Fluorouracil, doxorubicin, and cisplatin regimen in adrenal cortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Doxo | 1988 |