fluorouracil has been researched along with Adenoma in 36 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this review, we summarized the current status of our knowledge about the effectiveness of curcumin when given in combination with current chemotherapeutics such as 5-fluorouracil, oxaliplatin, and gemcitabine in treatment of gastrointestinal cancers with particular reference to colorectal cancer." | 8.85 | Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview. ( Majumdar, AP; Patel, BB, 2009) |
| "To investigate expression of cell cycle-related and expression-elevated protein in tumor (CREPT) in colorectal cancer (CRC) and determine its prognostic value in response to 5-fluorouracil (5-FU)." | 7.88 | Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil. ( Chang, ZJ; Ding, LD; Jia, BQ; Kuang, YS; Li, J; Liu, HY; Liu, SH; Wang, XN; Wang, Y; Wang, YY; Yang, L; Zhu, BT, 2018) |
| "Metformin is an old, inexpensive, and relatively safe anti-diabetic medication that can decrease the risk of several types of cancer in patients with diabetes." | 5.72 | The Emerging Role of Metformin in the Prevention and Treatment of Colorectal Cancer: A Game Changer for the Management of Colorectal Cancer. ( Ala, M, 2022) |
| " In vivo pellet coating led to reduced drug bioavailability and enhanced drug accumulation at colon (179." | 5.40 | Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment. ( Bose, A; Elyagoby, A; Wong, TW, 2014) |
| " In this review, we summarized the current status of our knowledge about the effectiveness of curcumin when given in combination with current chemotherapeutics such as 5-fluorouracil, oxaliplatin, and gemcitabine in treatment of gastrointestinal cancers with particular reference to colorectal cancer." | 4.85 | Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview. ( Majumdar, AP; Patel, BB, 2009) |
| "To investigate expression of cell cycle-related and expression-elevated protein in tumor (CREPT) in colorectal cancer (CRC) and determine its prognostic value in response to 5-fluorouracil (5-FU)." | 3.88 | Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil. ( Chang, ZJ; Ding, LD; Jia, BQ; Kuang, YS; Li, J; Liu, HY; Liu, SH; Wang, XN; Wang, Y; Wang, YY; Yang, L; Zhu, BT, 2018) |
| "Metformin is an old, inexpensive, and relatively safe anti-diabetic medication that can decrease the risk of several types of cancer in patients with diabetes." | 1.72 | The Emerging Role of Metformin in the Prevention and Treatment of Colorectal Cancer: A Game Changer for the Management of Colorectal Cancer. ( Ala, M, 2022) |
| " In vivo pellet coating led to reduced drug bioavailability and enhanced drug accumulation at colon (179." | 1.40 | Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment. ( Bose, A; Elyagoby, A; Wong, TW, 2014) |
| "Microsatellite instability was observed in all VCMsh2 strains and limited to the intestinal mucosa." | 1.36 | An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents. ( Bronson, RT; Clark, AB; Edelmann, W; Fan, K; Hou, H; Jelicks, L; Kucherlapati, MH; Kucherlapati, R; Kunkel, TA; Lee, K; Li, H; Lipkin, M; Nguyen, AA; Rosulek, A; Yang, K, 2010) |
| "Other nonneoplastic gastrointestinal disorders showed an 18% abnormal CSAp titer frequency, of which more than half bordered the upper limit of normalcy." | 1.26 | Colon-specific antigen-p (CSAp). I. Initial clinical evaluation as a marker for colorectal cancer. ( Goldenberg, DM; Nelson, MO; Pant, KD; Shochat, D, 1982) |
| "Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome." | 1.25 | The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (33.33) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 14 (38.89) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ala, M | 1 |
| Raghavan, R | 1 |
| Koyande, N | 1 |
| Beher, R | 1 |
| Chetlangia, N | 1 |
| Ramadwar, M | 1 |
| Pawade, S | 1 |
| Thorat, R | 1 |
| van Hengel, J | 1 |
| Sklyarova, T | 1 |
| van Roy, F | 1 |
| Dalal, SN | 1 |
| Igarashi, H | 1 |
| Taniguchi, H | 1 |
| Nosho, K | 1 |
| Ishigami, K | 1 |
| Koide, H | 1 |
| Mitsuhashi, K | 1 |
| Okita, K | 1 |
| Takemasa, I | 1 |
| Imai, K | 1 |
| Nakase, H | 1 |
| Lee, HS | 1 |
| Kim, SB | 1 |
| Lee, HJ | 1 |
| Park, SJ | 1 |
| Hong, SP | 1 |
| Cheon, JH | 1 |
| Kim, WH | 1 |
| Kim, TI | 1 |
| Kuang, YS | 1 |
| Wang, Y | 2 |
| Ding, LD | 1 |
| Yang, L | 1 |
| Liu, SH | 1 |
| Zhu, BT | 1 |
| Wang, XN | 1 |
| Liu, HY | 1 |
| Li, J | 1 |
| Chang, ZJ | 1 |
| Wang, YY | 1 |
| Jia, BQ | 1 |
| Lin, Z | 1 |
| Chen, J | 1 |
| Guo, Y | 1 |
| Miyazaki, T | 1 |
| Hasegawa, Y | 1 |
| Hanai, N | 1 |
| Ozawa, T | 1 |
| Hirakawa, H | 1 |
| Suzuki, A | 1 |
| Okamoto, H | 1 |
| Harata, I | 1 |
| Han, Y | 1 |
| Cai, H | 1 |
| Ma, L | 1 |
| Ding, Y | 1 |
| Tan, X | 1 |
| Liu, Y | 1 |
| Su, T | 1 |
| Yu, Y | 1 |
| Chang, W | 1 |
| Zhang, H | 1 |
| Fu, C | 1 |
| Cao, G | 1 |
| Zacharia, BE | 1 |
| Gulati, AP | 1 |
| Bruce, JN | 2 |
| Carminucci, AS | 1 |
| Wardlaw, SL | 1 |
| Siegelin, M | 1 |
| Remotti, H | 1 |
| Lignelli, A | 1 |
| Fine, RL | 2 |
| Bose, A | 1 |
| Elyagoby, A | 1 |
| Wong, TW | 1 |
| Stadler, ZK | 1 |
| Amankwatia, EB | 1 |
| Chakravarty, P | 1 |
| Carey, FA | 1 |
| Weidlich, S | 1 |
| Steele, RJ | 1 |
| Munro, AJ | 1 |
| Wolf, CR | 1 |
| Smith, G | 1 |
| Kucherlapati, MH | 1 |
| Lee, K | 1 |
| Nguyen, AA | 1 |
| Clark, AB | 1 |
| Hou, H | 1 |
| Rosulek, A | 1 |
| Li, H | 1 |
| Yang, K | 1 |
| Fan, K | 1 |
| Lipkin, M | 1 |
| Bronson, RT | 1 |
| Jelicks, L | 1 |
| Kunkel, TA | 1 |
| Kucherlapati, R | 1 |
| Edelmann, W | 1 |
| Thearle, MS | 1 |
| Freda, PU | 1 |
| Isaacson, SR | 1 |
| Lee, Y | 1 |
| Patel, BB | 1 |
| Majumdar, AP | 1 |
| Troisi, RI | 1 |
| Van Huysse, J | 1 |
| Berrevoet, F | 1 |
| Vandenbossche, B | 1 |
| Sainz-Barriga, M | 1 |
| Vinci, A | 1 |
| Ricciardi, S | 1 |
| Bocchetti, T | 1 |
| Rogiers, X | 1 |
| de Hemptinne, B | 1 |
| Darsigny, M | 1 |
| Babeu, JP | 1 |
| Seidman, EG | 1 |
| Gendron, FP | 1 |
| Levy, E | 1 |
| Carrier, J | 1 |
| Perreault, N | 1 |
| Boudreau, F | 1 |
| Gardini, A | 1 |
| Saragoni, L | 1 |
| La Barba, G | 1 |
| Serra, L | 1 |
| Calistri, D | 1 |
| Ulivi, P | 1 |
| Casadei, A | 1 |
| Frassineti, GL | 1 |
| Garcea, D | 1 |
| SULLIVAN, RD | 1 |
| ZUREK, WZ | 1 |
| Murphy, JT | 1 |
| Tucker, JM | 1 |
| Davis, C | 1 |
| Berger, FG | 1 |
| Jones, DH | 1 |
| Silberstein, PT | 1 |
| Lynch, H | 1 |
| Ternet, C | 1 |
| Armbrust, T | 1 |
| Sobotta, M | 1 |
| Füzesi, L | 1 |
| Grabbe, E | 1 |
| Ramadori, G | 1 |
| Brindley, GV | 1 |
| Bonnet, JD | 1 |
| Deregibus, P | 1 |
| Battezzati, G | 1 |
| Pant, KD | 1 |
| Shochat, D | 1 |
| Nelson, MO | 1 |
| Goldenberg, DM | 1 |
| Johjima, Y | 1 |
| Imamura, T | 1 |
| Shimazu, R | 1 |
| Ihara, O | 1 |
| Oohara, T | 1 |
| Murakami, T | 1 |
| Kondo, Y | 1 |
| Saeki, Y | 1 |
| Hosokawa, O | 1 |
| Yamamichi, N | 1 |
| Narisawa, T | 2 |
| Sato, M | 1 |
| Tani, M | 1 |
| Takahashi, T | 2 |
| Kohno, KI | 1 |
| Yamaguchi, T | 1 |
| McLachlan, SA | 1 |
| Millward, MJ | 1 |
| Toner, GC | 1 |
| Guiney, MJ | 1 |
| Bishop, JF | 1 |
| Green, RJ | 1 |
| Metlay, JP | 1 |
| Propert, K | 1 |
| Catalano, PJ | 1 |
| Macdonald, JS | 1 |
| Mayer, RJ | 1 |
| Haller, DG | 1 |
| Domoto, H | 1 |
| Tsuda, H | 1 |
| Miyakawa, K | 1 |
| Shinoda, A | 1 |
| Nanasawa, T | 1 |
| Britton, S | 1 |
| Thorén, M | 1 |
| Sjoberg, HE | 1 |
| Naess, A | 1 |
| Chevrel, B | 1 |
| Chevrel, JP | 1 |
| Brambilla, G | 1 |
| Caraceni, CE | 1 |
| Cavanna, M | 1 |
| Parodi, S | 1 |
2 reviews available for fluorouracil and Adenoma
| Article | Year |
|---|---|
Diagnosis and management of DNA mismatch repair-deficient colorectal cancer.
Topics: Adenoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; C | 2015 |
Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combine | 2009 |
34 other studies available for fluorouracil and Adenoma
| Article | Year |
|---|---|
The Emerging Role of Metformin in the Prevention and Treatment of Colorectal Cancer: A Game Changer for the Management of Colorectal Cancer.
Topics: Adenoma; Colorectal Neoplasms; Fluorouracil; Humans; Hypoglycemic Agents; Incidence; Metformin | 2022 |
Plakophilin3 loss leads to increased adenoma formation and rectal prolapse in APC
Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Colon; Colorectal Neoplasms; Disease Progression; | 2022 |
PRDM14 promotes malignant phenotype and correlates with poor prognosis in colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; | 2020 |
Postoperative adjuvant chemotherapy is associated with a lower incidence of colorectal adenomas in patients with previous colorectal cancer.
Topics: Adenoma; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonoscopy; Colorectal Neop | 2018 |
Overexpression of CREPT confers colorectal cancer sensitivity to fluorouracil.
Topics: Adenoma; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Carcinogenesis; Cell Cycle; | 2018 |
Efficacy of XELOX adjuvant chemotherapy for gastric mixed adenoneuroendocrine carcinoma: A case report.
Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Neuroendocrine; Ch | 2019 |
Survival impact of pulmonary metastasectomy for patients with head and neck cancer.
Topics: Adenoma; Antineoplastic Agents; Carcinoma; Cisplatin; Docetaxel; Female; Fluorouracil; Head and Neck | 2013 |
Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy.
Topics: Adenoma; Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biom | 2013 |
High response rates and prolonged survival in patients with corticotroph pituitary tumors and refractory Cushing disease from capecitabine and temozolomide (CAPTEM): a case series.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Ca | 2014 |
Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment.
Topics: Aberrant Crypt Foci; Adenocarcinoma; Adenoma; Administration, Oral; Animals; Antimetabolites, Antine | 2014 |
MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms.
Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Colorectal Neoplas | 2015 |
An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.
Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2010 |
Temozolomide (Temodar®) and capecitabine (Xeloda®) treatment of an aggressive corticotroph pituitary tumor.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Combined Chemotherapy Protocols; Capecitab | 2011 |
Evolution of laparoscopic left lateral sectionectomy without the Pringle maneuver: through resection of benign and malignant tumors to living liver donation.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Loss, Su | 2011 |
Hepatocyte nuclear factor-4alpha promotes gut neoplasia in mice and protects against the production of reactive oxygen species.
Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Female; Fluorouracil; Gene Exp | 2010 |
Challenge in differential diagnosis of a liver mass histologically defined as a metastatic lesion from an occult primary intestinal tumour. The importance of clinical findings and the limitations of histology and molecular profiles. A case report.
Topics: Adenoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intr | 2012 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
Raltitrexed increases tumorigenesis as a single agent yet exhibits anti-tumor synergy with 5-fluorouracil in ApcMin/+ mice.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Combined Chemotherapy Protocols | 2004 |
Regression of colorectal adenomas with intravenous cytotoxic chemotherapy in a patient with familial adenomatous polyposis.
Topics: Adenoma; Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; C | 2005 |
Chemotherapy-induced suppression to adenoma or complete suppression of the primary in patients with stage IV colorectal cancer: report of four cases.
Topics: Adenocarcinoma; Adenoma; Aged; Antineoplastic Agents; Colon; Colonic Polyps; Colonoscopy; Colorectal | 2007 |
Bronchial adenoma and the carcinoid syndrome.
Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Bronchial Neoplasms; Carcinoid Tumor; Chlorpromazi | 1967 |
[2 cases of sebaceous cancer observed at the Holy Spirit Hospital in Casale Monferrato in 1980].
Topics: Adenoma; Aged; Anal Gland Neoplasms; Animals; Bleomycin; Diagnosis, Differential; Dinitrochlorobenze | 1982 |
Colon-specific antigen-p (CSAp). I. Initial clinical evaluation as a marker for colorectal cancer.
Topics: Adenocarcinoma; Adenoma; Antigens, Neoplasm; Carcinoembryonic Antigen; Colonic Neoplasms; Epitopes; | 1982 |
Duodenal adenoma with atypia following oral administration of tegafur.
Topics: Adenoma; Duodenal Neoplasms; Fluorouracil; Humans; Male; Middle Aged; Postoperative Care; Stomach Ne | 1983 |
[Regression of adenomas in Gardner's syndrome induced by systemic chemotherapy].
Topics: Adenoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Gardner Syndrome; Huma | 1984 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neop | 1980 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with intrarectal dose of 5-FU on animal model.
Topics: Adenoma; Animals; Colonic Neoplasms; Female; Fluorouracil; Injections, Intraperitoneal; Methylnitros | 1980 |
The spectrum of 5-fluorouracil cardiotoxicity.
Topics: Adenoma; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Digestive System Neoplasms; Fema | 1994 |
Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089.
Topics: Adenoma; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Cohort Studies; Colonic Neoplasms; | 2002 |
Invasive ductal carcinoma associated with tubular adenoma of the breast.
Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Breast Neoplasms; Carcinoma | 2002 |
The immunological hazard of Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum | 1975 |
[Electrolyte secreting rectal tumor].
Topics: Adenoma; Aged; Fluorouracil; Humans; Male; Rectal Neoplasms; Water-Electrolyte Balance | 1971 |
[Gallbladder cancer].
Topics: Adenocarcinoma; Adenoma; Carcinoma; Cholelithiasis; Fluorouracil; Gallbladder Neoplasms; Humans; Mel | 1971 |
[Evaluation, in newborn Swiss mice, of the carcinogenic activity of some antineoplastic and immunosuppressive compounds].
Topics: Adenoma; Animals; Animals, Newborn; Antineoplastic Agents; Asparaginase; Azathioprine; Fluorouracil; | 1971 |