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fluorouracil and Adenoma, Pleomorphic

fluorouracil has been researched along with Adenoma, Pleomorphic in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Adenoma, Pleomorphic: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Carcinoma ex pleomorphic adenoma is a rare histologic subtype of salivary gland cancer with an overall poor prognosis."1.36Sustained response of carcinoma ex pleomorphic adenoma treated with trastuzumab and capecitabine. ( Kelly, RJ; Sharon, E; Szabo, E, 2010)
"Adenocarcinoma ex pleomorphic adenoma is a rare tumor, and thus the management of the tumor has not been established."1.33Adenocarcinoma ex pleomorphic adenoma of the head and neck: Report of five cases. ( Akagi, H; Kariya, S; Kosaka, M; Nishizaki, K; Orita, Y, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharon, E1
Kelly, RJ1
Szabo, E1
GEVAUDAN, P1
BONNEAU, H1
CHARREL, J1
DESIRE, G1
Kariya, S1
Kosaka, M1
Orita, Y1
Akagi, H1
Nishizaki, K1

Other Studies

3 other studies available for fluorouracil and Adenoma, Pleomorphic

ArticleYear
Sustained response of carcinoma ex pleomorphic adenoma treated with trastuzumab and capecitabine.
    Head & neck oncology, 2010, May-26, Volume: 2

    Topics: Adenoma, Pleomorphic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Comb

2010
[ON THE BEHAVIOR OF PRIMARY CULTURES OF MIXED PAROTID TUMORS, IN THE PRESENCE OF CYTOTOXIC PRODUCTS].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Adenoma, Pleomorphic; Cyclophosphamide; Fluorouracil; Humans; Mechlorethamine; Parotid Neoplasms; Ph

1964
Adenocarcinoma ex pleomorphic adenoma of the head and neck: Report of five cases.
    Auris, nasus, larynx, 2006, Volume: 33, Issue:1

    Topics: Adenoma, Pleomorphic; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Docet

2006