fluorouracil has been researched along with Adenocystic Carcinoma in 25 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine patients (5 males, 4 females; median age, 62 years) with recurrent high-grade malignancies of major (7 cases) and minor (2 cases) salivary gland origin (4 adenoid cystic carcinomas, 2 adenocarcinomas, 2 poorly differentiated carcinomas, 1 mixed malignant tumor) were treated with cisplatin (60 mg/m2), epirubicin (50 mg/m2) and 5-fluorouracil (600 mg/m2) (CEF) by intravenous injections on the first day of a 21-day regimen." | 7.67 | Cisplatin, epirubicin and 5-fluorouracil combination chemotherapy for recurrent carcinoma of the salivary gland. ( Airoldi, M; Brando, V; Gabriele, P; Giordano, C; Pedani, F, 1989) |
| "Nine patients (5 males, 4 females; median age, 62 years) with recurrent high-grade malignancies of major (7 cases) and minor (2 cases) salivary gland origin (4 adenoid cystic carcinomas, 2 adenocarcinomas, 2 poorly differentiated carcinomas, 1 mixed malignant tumor) were treated with cisplatin (60 mg/m2), epirubicin (50 mg/m2) and 5-fluorouracil (600 mg/m2) (CEF) by intravenous injections on the first day of a 21-day regimen." | 3.67 | Cisplatin, epirubicin and 5-fluorouracil combination chemotherapy for recurrent carcinoma of the salivary gland. ( Airoldi, M; Brando, V; Gabriele, P; Giordano, C; Pedani, F, 1989) |
| " A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C." | 3.66 | Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy. ( Budd, GT; Groppe, CW, 1983) |
| "Adenoid cystic carcinoma is a relatively rare tumour which arises in the parotid and submandibular salivary glands." | 2.68 | Cisplatin and 5-fluorouracil for symptom control in advanced salivary adenoid cystic carcinoma. ( A'Hern, RP; Archer, D; Breach, N; Constenla, DO; Gore, ME; Henk, JM; Hill, ME; Rhys-Evans, P, 1997) |
| "To observe the effect of garlic oil combined with 5-FU induced apoptosis of adenoid cystic carcinoma cell line ACC-M." | 1.40 | [Study on garlic oil combined with 5-FU induced apoptosis of adenoid cystic carcinoma cell line ACC-M]. ( Fan, Z; Li, Y; Ran, D; Wu, F; Yao, Y; Zhou, H; Zhu, Y, 2014) |
| "Twenty-five squamous cell carcinomas, 1 melanoma, 2 basocellular carcinomas and 2 adenoid cystic carcinomas were treated." | 1.33 | [The outcome of treatments for carcinoma of the external auditory canal]. ( Delalande, C; Dumas, G; Lavieille, JP; Reyt, E; Righini, Ch; Schmerber, S; Soriano, E, 2005) |
| " Combining medium dosage of angiogensis inhibitor with chemical drug may have synergistic result in inhibiting ACC growth." | 1.32 | [Combining of TNP-470 and 5-Fu in inhibition of adenoid cystic carcinoma in nude mice model]. ( Li, JQ; Meng, M; Meng, N; Nong, XL; Wang, DZ; Zhang, H; Zhou, N, 2004) |
| "Seventeen patients with adenocystic carcinoma have received 34 adequate trials of chemotherapy at Princess Margaret Hospital since 1969." | 1.26 | Chemotherapy for adenocystic carcinoma. ( Sutherland, DJ; Tannock, IF, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (36.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, L | 1 |
| Sun, Y | 1 |
| Ye, G | 1 |
| Zhao, Y | 1 |
| Wu, J | 1 |
| Hitre, E | 1 |
| Budai, B | 1 |
| Takácsi-Nagy, Z | 1 |
| Rubovszky, G | 1 |
| Tóth, E | 1 |
| Remenár, É | 1 |
| Polgár, C | 1 |
| Láng, I | 1 |
| Wei, L | 1 |
| Liang, X | 1 |
| Li, S | 1 |
| Liu, J | 1 |
| Wu, F | 1 |
| Zhou, H | 1 |
| Fan, Z | 1 |
| Zhu, Y | 1 |
| Li, Y | 1 |
| Yao, Y | 1 |
| Ran, D | 1 |
| Wang, XF | 1 |
| Wu, DM | 1 |
| Li, BX | 1 |
| Lu, YJ | 1 |
| Yang, BF | 1 |
| Ross, PJ | 1 |
| Teoh, EM | 1 |
| A'hern, RP | 2 |
| Rhys-Evans, PH | 1 |
| Harrington, KJ | 1 |
| Nutting, CM | 1 |
| Gore, ME | 2 |
| Bauduceau, O | 1 |
| Ceccaldi, B | 1 |
| Bernard, O | 1 |
| Dourhte, LM | 1 |
| Le Moulec, S | 1 |
| Hervé, R | 1 |
| JOHNSON, RO | 1 |
| LANGE, RD | 1 |
| KISKEN, WA | 1 |
| CURRERI, AR | 1 |
| Thavaraj, V | 1 |
| Sridhar, MR | 1 |
| Sethi, A | 1 |
| Arya, LS | 1 |
| Nong, XL | 1 |
| Wang, DZ | 1 |
| Meng, M | 1 |
| Zhou, N | 1 |
| Meng, N | 1 |
| Li, JQ | 1 |
| Zhang, H | 1 |
| Chetty, R | 1 |
| Serra, S | 1 |
| Hsieh, E | 1 |
| Schmerber, S | 1 |
| Righini, Ch | 1 |
| Soriano, E | 1 |
| Delalande, C | 1 |
| Dumas, G | 1 |
| Reyt, E | 1 |
| Lavieille, JP | 1 |
| Tannock, IF | 1 |
| Sutherland, DJ | 1 |
| Inuyama, Y | 1 |
| Horiuchi, M | 1 |
| Kohno, N | 1 |
| Mashino, S | 1 |
| Ozu, R | 1 |
| Asaoka, K | 1 |
| Budd, GT | 1 |
| Groppe, CW | 1 |
| Farhat, F | 1 |
| Kattan, J | 1 |
| Culine, S | 1 |
| Bekradda, M | 1 |
| Droz, JP | 1 |
| Hill, ME | 1 |
| Constenla, DO | 1 |
| Henk, JM | 1 |
| Rhys-Evans, P | 1 |
| Breach, N | 1 |
| Archer, D | 1 |
| Yasumatsu, R | 1 |
| Shinzato, Y | 1 |
| Nakashima, T | 1 |
| Inokuchi, A | 1 |
| Komiyama, S | 1 |
| Sasiaja, M | 1 |
| Funa, N | 1 |
| Kamata, M | 1 |
| Furutani, K | 1 |
| Matsumoto, A | 1 |
| Kodaira, T | 1 |
| Ferguson, MJ | 1 |
| Dewar, JA | 1 |
| Triozzi, PL | 1 |
| Brantley, A | 1 |
| Fisher, S | 1 |
| Cole, TB | 1 |
| Crocker, I | 1 |
| Huang, AT | 1 |
| Airoldi, M | 1 |
| Pedani, F | 1 |
| Brando, V | 1 |
| Gabriele, P | 1 |
| Giordano, C | 1 |
| Petursson, SR | 1 |
| Furusaka, T | 1 |
| Kida, A | 1 |
| Iida, H | 1 |
| Yokode, Y | 1 |
| Kikuchi, K | 1 |
| Tomita, H | 1 |
| Bassilios, MI | 1 |
| Ramm, C | 1 |
| Jarmolych, J | 1 |
| Goffin, FB | 1 |
1 review available for fluorouracil and Adenocystic Carcinoma
| Article | Year |
|---|---|
[Efficacy of the combination of 5 fluorouracil, adriamycin and cisplatin (FAP protocol) in the treatment of metastatic cylindroma. Apropos of a case with review of the literature].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Cisplatin; Dose-Re | 1994 |
3 trials available for fluorouracil and Adenocystic Carcinoma
| Article | Year |
|---|---|
Cetuximab and platinum-based chemoradio- or chemotherapy of patients with epidermal growth factor receptor expressing adenoid cystic carcinoma: a phase II trial.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemo | 2013 |
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Car | 1981 |
Cisplatin and 5-fluorouracil for symptom control in advanced salivary adenoid cystic carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Cisplatin; F | 1997 |
21 other studies available for fluorouracil and Adenocystic Carcinoma
| Article | Year |
|---|---|
Effects of CD133 expression on chemotherapy and drug sensitivity of adenoid cystic carcinoma.
Topics: AC133 Antigen; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subf | 2022 |
[Adenoid cystic carcinoma of the breast:report of 25 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neopl | 2014 |
[Study on garlic oil combined with 5-FU induced apoptosis of adenoid cystic carcinoma cell line ACC-M].
Topics: Allyl Compounds; Apoptosis; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Fluorouracil; Humans; Sulfi | 2014 |
Synergistic inhibitory effect of sulforaphane and 5-fluorouracil in high and low metastasis cell lines of salivary gland adenoid cystic carcinoma.
Topics: Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Carcinoma, Adenoid Cystic; Cell Line, Tumo | 2009 |
Epirubicin, cisplatin and protracted venous infusion 5-Fluorouracil chemotherapy for advanced salivary adenoid cystic carcinoma.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth | 2009 |
[Cylindroma of the trachea, a rate tumor with unusual evolution].
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 2003 |
INFUSION OF 5-FLUOROURACIL IN CYLINDROMA TREATMENT.
Topics: Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Basal Cell; Fluorouracil; Humans; Injections, Intra | 1964 |
Adenoid cystic carcinoma of the lacrimal gland.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Adenoid Cystic; Child; Combi | 2003 |
[Combining of TNP-470 and 5-Fu in inhibition of adenoid cystic carcinoma in nude mice model].
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cyclohexan | 2004 |
Basaloid squamous carcinoma of the anal canal with an adenoid cystic pattern: histologic and immunohistochemical reappraisal of an unusual variant.
Topics: Anal Canal; Antibiotics, Antineoplastic; Antigens, CD20; Antimetabolites, Antineoplastic; Antineopla | 2005 |
[The outcome of treatments for carcinoma of the external auditory canal].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth | 2005 |
Chemotherapy for adenocystic carcinoma.
Topics: Alkylating Agents; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Fluorouracil; Humans; Lung Neop | 1980 |
Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Doxorubicin; Drug | 1983 |
[A case of adenoid cystic carcinoma in epipharynx which responded to radiation and chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Combined Modality Therapy | 1998 |
Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Adenoid Cystic; Combined M | 2000 |
Locally recurrent adenoid cystic carcinoma of the left antrum: response to epirubicin, cisplatin and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Cisplatin; Disease-Free S | 2001 |
5-Fluorouracil, cyclophosphamide, and vincristine for adenoid cystic carcinoma of the head and neck.
Topics: Adult; Aged; Carcinoma, Adenoid Cystic; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neopla | 1987 |
Cisplatin, epirubicin and 5-fluorouracil combination chemotherapy for recurrent carcinoma of the salivary gland.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, A | 1989 |
Adenoid cystic carcinoma of the esophagus. Complete response to combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Adenoid Cystic; Cisplati | 1986 |
Combination chemotherapy with CDDP and 5-FU in head and neck cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cyst | 1986 |
Cylindroma of the right maxillary antrum. Case report.
Topics: Adult; Carcinoma, Adenoid Cystic; Fluorouracil; Humans; Infusions, Parenteral; Male; Maxillary Neopl | 1967 |