fluorouracil has been researched along with Adenocarcinoma, Sebaceous in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Adenocarcinoma, Sebaceous: A malignant tumor composed of cells showing differentiation toward sebaceous epithelium. The tumor is solitary, firm, somewhat raised, more or less translucent, and covered with normal or slightly verrucose epidermis. It may be yellow or orange. The face and scalp are the commonest sites. The growth can be slow or rapid but metastasis is uncommon. Surgery cures most of the cases. (From Rook et al., Textbook of Dermatology, 4th ed, pp2403-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 55-year-old Asian Indian woman who had recurrent sebaceous gland carcinoma of the left lower eyelid with orbital extension and regional lymph node metastasis was treated with neoadjuvant chemotherapy, using a combination of carboplatin and 5-fluorouracil." | 3.73 | Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis. ( Burman, S; Honavar, SG; Murthy, R; Naik, MN; Reddy, VA; Vemuganti, GK, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SH | 1 |
| Jung, YH | 2 |
| Yoo, JY | 1 |
| Park, HJ | 1 |
| Gogia, A | 1 |
| Pushker, N | 1 |
| Sen, S | 1 |
| Bakhshi, S | 1 |
| Woo, IS | 1 |
| Kim, MY | 1 |
| Han, CW | 1 |
| Rha, EY | 1 |
| Murthy, R | 1 |
| Honavar, SG | 1 |
| Burman, S | 1 |
| Vemuganti, GK | 1 |
| Naik, MN | 1 |
| Reddy, VA | 1 |
4 other studies available for fluorouracil and Adenocarcinoma, Sebaceous
| Article | Year |
|---|---|
A Case Report of Recurrent Metastatic Sebaceous Carcinoma Which Showed Favorable Response Tt Non-Fluorouracil Based Chemotherapy.
Topics: Adenocarcinoma, Sebaceous; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Doxorubic | 2018 |
Avoidance of exenteration in orbital sebaceous gland carcinoma with neoadjuvant chemotherapy.
Topics: Adenocarcinoma, Sebaceous; Cisplatin; Eye Evisceration; Eyelid Neoplasms; Fluorouracil; Humans; Male | 2013 |
Palliative 5-fluorouracil and cisplatin chemotherapy in recurrent metastatic sebaceous carcinoma: Case report and literature review.
Topics: Adenocarcinoma, Sebaceous; Aged; Antineoplastic Combined Chemotherapy Protocols; Asia; Cisplatin; Fe | 2016 |
Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis.
Topics: Adenocarcinoma, Sebaceous; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Eyelid Neopl | 2005 |