fluorouracil has been researched along with Adenocarcinoma, Clear Cell in 15 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Adenocarcinoma, Clear Cell: An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "All patients had surgically documented minimal residual disease (1." | 2.68 | Intraperitoneal administration of cisplatin and 5-fluorouracil in residual ovarian cancer: a Phase II Gynecologic Oncology Group trial. ( Averette, H; Berek, JS; Blessing, JA; Braly, PS; Homesley, HD, 1995) |
| "Endometriosis was not independently associated with the prognosis of the OCCC patients, even when the tumor was confined to stage I." | 1.43 | Prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma: Experiences at three academic institutions. ( Bai, H; Cao, D; Chen, J; Sha, G; Shen, K; Wang, Y; Yang, J; Yuan, F; Zhang, Z, 2016) |
| "Herein, we report two cases of female urethral cancer." | 1.34 | [Two cases of primary female urethral cancer]. ( Bando, S; Inai, T; Kanda, K; Koizumi, T, 2007) |
| "Renal cell carcinoma is an uncommon tumor in adults." | 1.33 | Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma. ( Alcaide-García, J; Alés-Díaz, I; Benavides-Orgaz, M; Cobo-Dols, M; Gil-Calle, S; Gutiérrez-Calderón, V; Montesa-Pino, A; Villar-Chamorro, E, 2006) |
| "Paclitaxel was more effective in clear cells than serous papillary cells." | 1.31 | Cyclophosphamide and 5-fluorouracil act synergistically in ovarian clear cell adenocarcinoma cells. ( Gorai, I; Hirahara, F; Kawata, N; Miyamoto, Y; Ohta, I; Shirotake, S; Yang, J; Zheng, JH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hough, NE | 1 |
| Chapman, SJ | 1 |
| Flight, WG | 1 |
| Bai, H | 1 |
| Cao, D | 1 |
| Yuan, F | 1 |
| Sha, G | 1 |
| Yang, J | 2 |
| Chen, J | 1 |
| Wang, Y | 1 |
| Zhang, Z | 1 |
| Shen, K | 1 |
| Tan, YT | 1 |
| Zhang, X | 1 |
| Lin, ZQ | 1 |
| Chen, Q | 1 |
| Wang, LJ | 1 |
| Zhang, BZ | 1 |
| Kim, YS | 1 |
| Kim, JH | 2 |
| Ahn, SD | 1 |
| Lee, SW | 1 |
| Shin, SS | 1 |
| Nam, JH | 1 |
| Kim, YT | 1 |
| Kim, YM | 1 |
| Choi, EK | 1 |
| Davis, R | 1 |
| Peterson, AC | 1 |
| Lance, R | 1 |
| Cobo-Dols, M | 1 |
| Alés-Díaz, I | 1 |
| Villar-Chamorro, E | 1 |
| Gil-Calle, S | 1 |
| Alcaide-García, J | 1 |
| Montesa-Pino, A | 1 |
| Gutiérrez-Calderón, V | 1 |
| Benavides-Orgaz, M | 1 |
| Koizumi, T | 1 |
| Bando, S | 1 |
| Kanda, K | 1 |
| Inai, T | 1 |
| Braly, PS | 1 |
| Berek, JS | 1 |
| Blessing, JA | 1 |
| Homesley, HD | 1 |
| Averette, H | 1 |
| Rakovitch, E | 1 |
| Fyles, AW | 1 |
| Pintilie, M | 1 |
| Leung, PM | 1 |
| Mertens, R | 1 |
| Granzen, B | 1 |
| Lassay, L | 1 |
| Gademann, G | 1 |
| Hess, CF | 1 |
| Heimann, G | 1 |
| Chauffert, B | 1 |
| Bonnotte, B | 1 |
| Chvetzoff, G | 1 |
| Flesch, M | 1 |
| Sakaihara, M | 1 |
| Sakai, K | 1 |
| Hara, Y | 1 |
| Kataoka, S | 1 |
| Tabata, M | 1 |
| Hanatani, K | 1 |
| Hareyama, H | 1 |
| Pan, CC | 1 |
| Chiang, H | 1 |
| Chang, YH | 1 |
| Epstein, JI | 1 |
| Ohta, I | 1 |
| Gorai, I | 1 |
| Miyamoto, Y | 1 |
| Zheng, JH | 1 |
| Kawata, N | 1 |
| Hirahara, F | 1 |
| Shirotake, S | 1 |
| Amato, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT01849107] | 49 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for fluorouracil and Adenocarcinoma, Clear Cell
| Article | Year |
|---|---|
Gastrointestinal malignancy in cystic fibrosis.
Topics: Adenocarcinoma, Clear Cell; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; C | 2020 |
[Primary clear cell carcinoma of the cervix: report of five cases and review of the literature].
Topics: Adenocarcinoma, Clear Cell; Adult; Antineoplastic Combined Chemotherapy Protocols; CA-125 Antigen; C | 2008 |
2 trials available for fluorouracil and Adenocarcinoma, Clear Cell
| Article | Year |
|---|---|
Intraperitoneal administration of cisplatin and 5-fluorouracil in residual ovarian cancer: a Phase II Gynecologic Oncology Group trial.
Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adult; Aged; Antineoplastic Combined Chemotherapy Protoc | 1995 |
Nasopharyngeal carcinoma in childhood and adolescence: concept and preliminary results of the cooperative GPOH study NPC-91. Gesellschaft für Pädiatrische Onkologie und Hämatologie.
Topics: Adenocarcinoma, Clear Cell; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; C | 1997 |
11 other studies available for fluorouracil and Adenocarcinoma, Clear Cell
| Article | Year |
|---|---|
Prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma: Experiences at three academic institutions.
Topics: Adenocarcinoma, Clear Cell; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-125 Antigen; Ca | 2016 |
High-dose extended-field irradiation and high-dose-rate brachytherapy with concurrent chemotherapy for cervical cancer with positive para-aortic lymph nodes.
Topics: Adenocarcinoma, Clear Cell; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Carc | 2009 |
Clear cell adenocarcinoma in a female urethral diverticulum.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, | 2003 |
Solitary metastasis in a nasal fossa as the first manifestation of a renal carcinoma.
Topics: Adenocarcinoma, Clear Cell; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Carc | 2006 |
[Two cases of primary female urethral cancer].
Topics: Adenocarcinoma, Clear Cell; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamou | 2007 |
Role of mitomycin C in the development of late bowel toxicity following chemoradiation for locally advanced carcinoma of the cervix.
Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplas | 1997 |
[The major response of metastatic kidney cancer to the combination of oxaliplatin, 5-fluorouracil and folinic acid (FOX-FOL)].
Topics: Adenocarcinoma, Clear Cell; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antin | 1998 |
[Successful treatment of a patient with recurrent ovarian clear cell adenocarcinoma under combination chemotherapy of 5-FU (civ) and low-dose CDDP (i.v.)].
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administ | 2000 |
Tubulocystic clear cell adenocarcinoma arising within the prostate.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Fluor | 2000 |
Cyclophosphamide and 5-fluorouracil act synergistically in ovarian clear cell adenocarcinoma cells.
Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cisplatin | 2001 |
Thalidomide for recurrent renal-cell cancer in a 40-year-old man.
Topics: Adenocarcinoma, Clear Cell; Adult; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Drug Therapy, Com | 2000 |