Page last updated: 2024-10-27

fluorouracil and Addison's Disease

fluorouracil has been researched along with Addison's Disease in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iqbal, MS1
Hardman, J1
Roginsky, MS1
Schick, M1

Reviews

1 review available for fluorouracil and Addison's Disease

ArticleYear
Addisonian crisis secondary to bilateral adrenal metastases in rectal carcinoma: report of a rare case and literature review.
    Journal of gastrointestinal cancer, 2013, Volume: 44, Issue:2

    Topics: Addison Disease; Adenocarcinoma; Adrenal Gland Neoplasms; Antimetabolites, Antineoplastic; Capecitab

2013

Other Studies

1 other study available for fluorouracil and Addison's Disease

ArticleYear
Addison's disease following combined chemotherapy for hyperfunctioning adrenocortical carcinoma.
    Archives of internal medicine, 1966, Volume: 117, Issue:5

    Topics: Addison Disease; Adolescent; Adrenal Gland Neoplasms; Antineoplastic Agents; Dichlorodiphenyldichlor

1966