fluorouracil has been researched along with Addison's Disease in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iqbal, MS | 1 |
| Hardman, J | 1 |
| Roginsky, MS | 1 |
| Schick, M | 1 |
1 review available for fluorouracil and Addison's Disease
| Article | Year |
|---|---|
Addisonian crisis secondary to bilateral adrenal metastases in rectal carcinoma: report of a rare case and literature review.
Topics: Addison Disease; Adenocarcinoma; Adrenal Gland Neoplasms; Antimetabolites, Antineoplastic; Capecitab | 2013 |
1 other study available for fluorouracil and Addison's Disease
| Article | Year |
|---|---|
Addison's disease following combined chemotherapy for hyperfunctioning adrenocortical carcinoma.
Topics: Addison Disease; Adolescent; Adrenal Gland Neoplasms; Antineoplastic Agents; Dichlorodiphenyldichlor | 1966 |