fluorouracil has been researched along with Acute Necrotizing Pancreatitis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capecitabine is an orally administered pro-drug of 5-fluorouracil that confers superior disease-free survival and presumably has a more favourable side-effect profile." | 1.38 | Hypertriglyceridaemia-induced pancreatitis: a contributory role of capecitabine? ( Chan, AO; Chan, HY; Ng, CM; Shek, CC; Tiu, SC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YJ | 1 |
| Cho, E | 1 |
| Park, CH | 1 |
| Chan, HY | 1 |
| Ng, CM | 1 |
| Tiu, SC | 1 |
| Chan, AO | 1 |
| Shek, CC | 1 |
2 other studies available for fluorouracil and Acute Necrotizing Pancreatitis
| Article | Year |
|---|---|
Endoscopic drainage for management of infected necrosis following EUS-TA in a patient with pancreatic cancer: A case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Pancreatic Ductal; Drainage | 2021 |
Hypertriglyceridaemia-induced pancreatitis: a contributory role of capecitabine?
Topics: Administration, Oral; Adult; Antimetabolites, Antineoplastic; Capecitabine; Colonic Neoplasms; Deoxy | 2012 |