fluorouracil has been researched along with Acute Coronary Syndrome in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU) is considered to be the backbone of colorectal cancer (CRC) systemic therapy since the great majority of recommended regimens include its administration." | 7.75 | Acute coronary syndrome associated with continuous 5-Fluorouracil infusion in a patient with metastatic colorectal cancer-a case report with a discussion on this clinical dilemma. ( Garita, R; Michelin, OC; Okoshi, K; Paiva, BS; Paiva, CE, 2009) |
| "5-Fluorouracil (5-FU) is considered to be the backbone of colorectal cancer (CRC) systemic therapy since the great majority of recommended regimens include its administration." | 3.75 | Acute coronary syndrome associated with continuous 5-Fluorouracil infusion in a patient with metastatic colorectal cancer-a case report with a discussion on this clinical dilemma. ( Garita, R; Michelin, OC; Okoshi, K; Paiva, BS; Paiva, CE, 2009) |
| "5-Fluorouracil is a first-line agent in several cancer-therapy regimens." | 1.48 | Acute coronary syndrome in the oncology patient: An avoidable event? ( Félix-Oliveira, A; Madeira, S; Mendes, M; Vale, N, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Das, SK | 1 |
| Das, AK | 1 |
| William, M | 1 |
| Kounis, NG | 1 |
| Koniari, I | 1 |
| Patsouras, N | 1 |
| Koutsogiannis, N | 1 |
| Velissaris, D | 1 |
| Soufras, G | 1 |
| Hahalis, G | 1 |
| Félix-Oliveira, A | 1 |
| Vale, N | 1 |
| Madeira, S | 1 |
| Mendes, M | 1 |
| Redana, S | 1 |
| Sharp, A | 1 |
| Lote, H | 1 |
| Mohammed, K | 1 |
| Papadimitraki, E | 1 |
| Capelan, M | 1 |
| Ring, A | 1 |
| Paiva, CE | 1 |
| Paiva, BS | 1 |
| Garita, R | 1 |
| Michelin, OC | 1 |
| Okoshi, K | 1 |
| Garcipérez de Vargas, FJ | 1 |
| Gómez Barrado, JJ | 1 |
| Mendoza Vázquez, J | 1 |
| Ortiz Cortés, C | 1 |
| Spencker, S | 1 |
| Schmittel, A | 1 |
| Westermann, D | 1 |
| Marek, A | 1 |
| Schultheiss, HP | 1 |
| Witzenbichler, B | 1 |
| Martí, V | 1 |
| Monell, J | 1 |
| Seixo, F | 1 |
| Falces, C | 1 |
8 other studies available for fluorouracil and Acute Coronary Syndrome
| Article | Year |
|---|---|
5-Fluorouracil-induced acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Antimetabolites, Antineoplastic; Chest Pain; Coronary Angiography; El | 2019 |
Coronary vasospasm associated with 5-fluorouracil chemotherapy: Cardiac toxicity or cardiac hypersensitivity?
Topics: Acute Coronary Syndrome; Cardiotoxicity; Coronary Vasospasm; Drug Hypersensitivity; Fluorouracil; Hu | 2017 |
Acute coronary syndrome in the oncology patient: An avoidable event?
Topics: Acute Coronary Syndrome; Angioplasty; Antineoplastic Agents; Colonic Neoplasms; Duodenal Neoplasms; | 2018 |
Rates of major complications during neoadjuvant and adjuvant chemotherapy for early breast cancer: An off study population.
Topics: Acute Coronary Syndrome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas | 2016 |
Acute coronary syndrome associated with continuous 5-Fluorouracil infusion in a patient with metastatic colorectal cancer-a case report with a discussion on this clinical dilemma.
Topics: Acute Coronary Syndrome; Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; | 2009 |
[Acute coronary syndrome in patient treated with capecitabine].
Topics: Acute Coronary Syndrome; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorou | 2012 |
[Angina pectoris and ST-elevation after chemotherapy with 5-fluorouracil].
Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Antineoplastic Combined Chemotherapy Protocols; Carc | 2007 |
[Acute coronary syndrome during oral capecitabine monotherapy].
Topics: Acute Coronary Syndrome; Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Deoxyc | 2008 |