Page last updated: 2024-10-27

fluorouracil and Acute Brain Injuries

fluorouracil has been researched along with Acute Brain Injuries in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effect of 5-fluorouracil mobilized bone marrow regenerative cells (BMRCs) transplantation on brain injury following focal cerebral ischemia and to explore the mechanisms."7.81Effect of 5-fluorouracil mobilized bone marrow regenerative cells transplantation on brain injury following focal cerebral ischemia in rats. ( Li, M; Liao, H; Liu, XL; Xiao, LH; Xu, FF; Xu, ZP; Yang, B, 2015)
"The aim of this study was to evaluate the effect of 5-fluorouracil mobilized bone marrow regenerative cells (BMRCs) transplantation on brain injury following focal cerebral ischemia and to explore the mechanisms."3.81Effect of 5-fluorouracil mobilized bone marrow regenerative cells transplantation on brain injury following focal cerebral ischemia in rats. ( Li, M; Liao, H; Liu, XL; Xiao, LH; Xu, FF; Xu, ZP; Yang, B, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, FF1
Liu, XL1
Li, M1
Yang, B1
Liao, H1
Xiao, LH1
Xu, ZP1
Nishimura, K1
Inoue, T1
Yoshimoto, K1
Taniguchi, T1
Kitamura, Y1
Agata, K1

Other Studies

2 other studies available for fluorouracil and Acute Brain Injuries

ArticleYear
Effect of 5-fluorouracil mobilized bone marrow regenerative cells transplantation on brain injury following focal cerebral ischemia in rats.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:11

    Topics: Administration, Intravenous; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Brain Injuries

2015
Regeneration of dopaminergic neurons after 6-hydroxydopamine-induced lesion in planarian brain.
    Journal of neurochemistry, 2011, Volume: 119, Issue:6

    Topics: Analysis of Variance; Animals; Brain Injuries; Bromodeoxyuridine; Cell Cycle; Cell Movement; Cell Pr

2011
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