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fluorouracil and Acquired Metabolic Diseases, Brain

fluorouracil has been researched along with Acquired Metabolic Diseases, Brain in 5 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okamura, T1
Kawachi, Y1
Nikkuni, K1
Nishimura, A1
Makino, S1
Kawahara, M1
Kitami, C1
Hashimoto, Y1
Nakano, E1
Kuroki, M1
Kanno, N1
Matsumura, Y1
Miura, A1
Kikuchi, Y1
Hirakawa, H1
Teraishi, F1
Suzuki, T1
Nakamoto, M1
Chikuba, A1
Nezu, M1
Shimamura, H1
Watanabe, T1
Matsuda, T1
Takiue, T1
Chikuba, H1
Shiihara, T1
Kato, M1
Hayasaka, K1
Liaw, CC1
Liaw, SJ1
Wang, CH1
Chiu, MC1
Huang, JS1

Other Studies

5 other studies available for fluorouracil and Acquired Metabolic Diseases, Brain

ArticleYear
[A case of hyperammonemic encephalopathy related to 5-FU in an aged patient with recurrent colon cancer treated with FOLFIRI therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Brain Dise

2013
[A case of metastatic colorectal cancer with hyperammonemic encephalopathy induced by 5-FU in a patient continuously treated with XELOX therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:13

    Topics: Amino Acids, Branched-Chain; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases, Metabol

2013
[A case of hyperammonemic encephalopathy in a patient with recurrent colon cancer treated with modified FOLFOX6].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases, Metabolic; Colonic Neoplasms;

2009
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Adolescent; Brain Diseases, Metabolic; Corpus Callosum; Diagnosis, Differential; DNA, Mitochondrial;

2005
Transient hyperammonemia related to chemotherapy with continuous infusion of high-dose 5-fluorouracil.
    Anti-cancer drugs, 1993, Volume: 4, Issue:3

    Topics: Adult; Aged; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases, Metabolic; Dos

1993