fluorouracil has been researched along with Acquired Laryngeal Stenosis in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models." | 7.85 | The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017) |
| "The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment." | 7.81 | A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015) |
| "We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment." | 7.78 | Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012) |
| "The aim of this study is to evaluate the efficacy of ethosomes encapsulated with 5-fluorouracil (5-FU) in treatment of laryngotracheal stenosis in rabbit models." | 3.85 | The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models. ( Cheng, X; Mao, X; Wang, Z; Zhang, Z, 2017) |
| "The purpose of our article was to explore the effect of ethosomes containing 5-fluorouracil (5-FU) with different sizes on laryngotracheal stenosis treatment." | 3.81 | A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil. ( Ao, H; Gu, J; Li, C; Mao, X; Yang, X, 2015) |
| "We aimed to investigate the prophylactic effect of pentoxifylline (PTX) and 5-fluorouracil (5-FU) on laryngotracheal stenosis in tracheotomised rats by evaluating blood glutathione peroxidase (GPx) and superoxide dismutase activities and by histopathological evaluation of laryngotracheal segment." | 3.78 | Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats. ( Ekici, A; Eyibilen, A; Kıyıcı, H; Koc, S; Salman, N; Söğüt, E, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, J | 1 |
| Mao, X | 2 |
| Li, C | 1 |
| Ao, H | 1 |
| Yang, X | 1 |
| Cheng, X | 1 |
| Zhang, Z | 1 |
| Wang, Z | 2 |
| Hirshoren, N | 1 |
| Eliashar, R | 1 |
| Koc, S | 1 |
| Kıyıcı, H | 1 |
| Söğüt, E | 1 |
| Eyibilen, A | 1 |
| Ekici, A | 1 |
| Salman, N | 1 |
| Ingrams, DR | 2 |
| Sukin, SW | 1 |
| Ashton, P | 2 |
| Valtonen, HJ | 1 |
| Pankratov, MM | 1 |
| Shapshay, SM | 2 |
| Dhingra, J | 1 |
| Shah, R | 1 |
1 review available for fluorouracil and Acquired Laryngeal Stenosis
| Article | Year |
|---|---|
Wound-healing modulation in upper airway stenosis-Myths and facts.
Topics: Acetylcysteine; Aminopropionitrile; Animals; Antimetabolites; Colchicine; Fluorouracil; Humans; Hype | 2009 |
5 other studies available for fluorouracil and Acquired Laryngeal Stenosis
| Article | Year |
|---|---|
A Novel Therapy for Laryngotracheal Stenosis: Treatment With Ethosomes Containing 5-Fluorouracil.
Topics: Animals; Disease Models, Animal; Female; Fluorouracil; Immunosuppressive Agents; Laryngostenosis; Li | 2015 |
The therapy with ethosomes containing 5-fluorouracil for laryngotracheal stenosis in rabbit models.
Topics: Animals; Antimetabolites; Drug Administration Schedule; Drug Delivery Systems; Female; Fluorouracil; | 2017 |
Effect of pentoxifylline and 5-fluorouracil/triamcinolone on laryngotracheal stenosis developing as a complication of tracheostomy: study in rats.
Topics: Animals; Biological Availability; Female; Fluorouracil; Glucocorticoids; Glutathione Peroxidase; Imm | 2012 |
Does slow-release 5-fluorouracil and triamcinolone reduce subglottic stenosis?
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Cell Movement; Delayed-Action Pr | 1998 |
Slow-release 5-fluorouracil and triamcinolone reduces subglottic stenosis in a rabbit model.
Topics: Animals; Delayed-Action Preparations; Drug Combinations; Fluorouracil; Glottis; Injections; Laryngos | 2000 |