fluorouracil has been researched along with Acne Rosacea in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Background Topical 5-fluorouracil (5-FU) is an antineoplastic antimetabolite used for the treatment of actinic keratosis." | 8.93 | 5-Fluorouracil-induced exacerbation of rosacea. ( Cohen, PR; Haddock, ES, 2016) |
| "Background Topical 5-fluorouracil (5-FU) is an antineoplastic antimetabolite used for the treatment of actinic keratosis." | 4.93 | 5-Fluorouracil-induced exacerbation of rosacea. ( Cohen, PR; Haddock, ES, 2016) |
| "The rosacea was associated with episodes of diarrhoea." | 1.29 | [Carcinoid tumor with revealed by skin manifestation]. ( Cuny, JF; Grandidier, M; Reichert, S; Truchetet, F, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haddock, ES | 1 |
| Cohen, PR | 1 |
| Reichert, S | 1 |
| Truchetet, F | 1 |
| Cuny, JF | 1 |
| Grandidier, M | 1 |
1 review available for fluorouracil and Acne Rosacea
| Article | Year |
|---|---|
5-Fluorouracil-induced exacerbation of rosacea.
Topics: Administration, Cutaneous; Aged; Antineoplastic Agents; Disease Progression; Fluorouracil; Humans; K | 2016 |
1 other study available for fluorouracil and Acne Rosacea
| Article | Year |
|---|---|
[Carcinoid tumor with revealed by skin manifestation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Combined Modality Therapy; Facial D | 1994 |