fluorouracil has been researched along with Acidosis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kondo, K | 1 |
| Fujiwara, M | 1 |
| Murase, M | 1 |
| Kodera, Y | 1 |
| Akiyama, S | 1 |
| Ito, K | 1 |
| Takagi, H | 1 |
| Yeh, KH | 1 |
| Cheng, AL | 1 |
2 other studies available for fluorouracil and Acidosis
| Article | Year |
|---|---|
Severe acute metabolic acidosis and Wernicke's encephalopathy following chemotherapy with 5-fluorouracil and cisplatin: case report and review of the literature.
Topics: Acidosis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; F | 1996 |
High-dose 5-fluorouracil infusional therapy is associated with hyperammonaemia, lactic acidosis and encephalopathy.
Topics: Acidosis; Ammonia; Antimetabolites, Antineoplastic; Brain Diseases; Coma; Diagnosis, Differential; E | 1997 |