Page last updated: 2024-10-27

fluorouracil and Acidosis, Diabetic

fluorouracil has been researched along with Acidosis, Diabetic in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The development of diabetic ketoacidosis is an unusual complication of a glucagon-secreting pancreatic islet cell neoplasm, with only four reported cases in the literature."1.29Case report: diabetic ketoacidosis in a patient with glucagonoma. ( Anthony, LB; May, ME; Sharp, SC, 1995)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anthony, LB1
Sharp, SC1
May, ME1
Gailani, S1
Holland, JF1
Falkson, G1
Leone, L1
Burningham, R1
Larsen, V1

Trials

1 trial available for fluorouracil and Acidosis, Diabetic

ArticleYear
Comparison of treatment of metastatic gastrointestinal cancer with 5-fluorouracil (5-FU) to a combination of 5-FU with cytosine arabinoside.
    Cancer, 1972, Volume: 29, Issue:5

    Topics: Adenocarcinoma; Clinical Trials as Topic; Colonic Neoplasms; Cytarabine; Diabetic Ketoacidosis; Diar

1972

Other Studies

1 other study available for fluorouracil and Acidosis, Diabetic

ArticleYear
Case report: diabetic ketoacidosis in a patient with glucagonoma.
    The American journal of the medical sciences, 1995, Volume: 309, Issue:6

    Topics: Diabetic Ketoacidosis; Female; Fluid Therapy; Fluorouracil; Glucagonoma; Humans; Insulin; Middle Age

1995