Page last updated: 2024-10-27

fluorouracil and Acanthamoeba Keratitis

fluorouracil has been researched along with Acanthamoeba Keratitis in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Acanthamoeba Keratitis: Infection of the cornea by an ameboid protozoan which may cause corneal ulceration leading to blindness.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Saeed, BQ1
Qalaji, MR1
Akbar, N1
Siddiqui, R1
Roberta, C1
Manzoor, S1
Muhammad, JS1
Adrees, AO1
Al-Shahrabi, R1
Khan, NA1

Other Studies

1 other study available for fluorouracil and Acanthamoeba Keratitis

ArticleYear
Evaluation of nanoparticles with 5-fluorouracil and chloroquine on Acanthamoeba castellanii activity.
    Molecular and biochemical parasitology, 2022, Volume: 250

    Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Amebicides; Chloroquine; Fluorouracil; Humans; Nan

2022