fluorouracil has been researched along with Abnormalities, Digestive System in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Sanna'a, NA | 1 |
| Van Kuilenburg, AB | 1 |
| Atrak, TM | 1 |
| Abdul-Jabbar, MA | 1 |
| Van Gennip, AH | 1 |
| Stephens, JD | 1 |
| Golbus, MS | 1 |
| Miller, TR | 1 |
| Wilber, RR | 1 |
| Epstein, CJ | 1 |
2 other studies available for fluorouracil and Abnormalities, Digestive System
| Article | Year |
|---|---|
Dihydropyrimidine dehydrogenase deficiency presenting at birth.
Topics: Age of Onset; Antimetabolites; Binding Sites; Digestive System Abnormalities; Dihydropyrimidine Dehy | 2005 |
Multiple congenital anomalies in a fetus exposed to 5-fluorouracil during the first trimester.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Bone and Bones; Digestive System Abnorm | 1980 |