Page last updated: 2024-10-27

fluorouracil and Abnormal Karyotype

fluorouracil has been researched along with Abnormal Karyotype in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Abnormal Karyotype: A variation from the normal set of chromosomes characteristic of a species.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Damodaran, S1
Bellavia, T1
Sait, SN1
Wang, ES1
Wetzler, M1
Khushalani, NI1

Other Studies

1 other study available for fluorouracil and Abnormal Karyotype

ArticleYear
Acute myeloid leukemia secondary to oxaliplatin treatment for esophageal cancer.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:2

    Topics: Abnormal Karyotype; Adenocarcinoma; Antineoplastic Agents; Capecitabine; Clinical Trials, Phase II a

2012