fluorouracil has been researched along with Abdominal Obesity in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with colon cancer who prematurely discontinue postoperative chemotherapy may have an increased risk of disease recurrence and death." | 1.72 | The association of abdominal adiposity with premature discontinuation of postoperative chemotherapy in colon cancer. ( Brown, JC; Caan, BJ; Cespedes Feliciano, EM; Cheng, E; Meyerhardt, JA, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, JC | 1 |
| Meyerhardt, JA | 1 |
| Cespedes Feliciano, EM | 1 |
| Cheng, E | 1 |
| Caan, BJ | 1 |
1 other study available for fluorouracil and Abdominal Obesity
| Article | Year |
|---|---|
The association of abdominal adiposity with premature discontinuation of postoperative chemotherapy in colon cancer.
Topics: Adiposity; Cohort Studies; Colonic Neoplasms; Fluorouracil; Humans; Leucovorin; Neoplasm Recurrence, | 2022 |