Page last updated: 2024-10-27

fluorouracil and ATLL

fluorouracil has been researched along with ATLL in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The involvement of S-1 chemotherapy in ATLL development suggests that a test for HTLV-1 antibody should be performed before treatment and that S-1 should not be administered in HTLV-1 positive patients with head and neck carcinoma."1.46Adult T-cell leukemia/lymphoma in patients with head and neck cancer after S-1 chemotherapy. ( Kurono, Y; Matushita, K; Nagano, H, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagano, H1
Kurono, Y1
Matushita, K1
Yusa, K1
Oh-hara, T1
Tsuruo, T1
Huschtscha, LI1
Bartier, WA1
Ross, CE1
Tattersall, MH1

Other Studies

3 other studies available for fluorouracil and ATLL

ArticleYear
Adult T-cell leukemia/lymphoma in patients with head and neck cancer after S-1 chemotherapy.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C

2017
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus.
    Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2

    Topics: Cell Division; Cell Line; Cell Survival; Cytarabine; Cytidine Deaminase; Drug Resistance; Fluorourac

1995
Characteristics of cancer cell death after exposure to cytotoxic drugs in vitro.
    British journal of cancer, 1996, Volume: 73, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Dexamethasone; DNA, Neoplasm; Flow Cytomet

1996