Page last updated: 2024-10-27

fluorouracil and ANCA-Associated Vasculitides

fluorouracil has been researched along with ANCA-Associated Vasculitides in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ntatsaki, E1
Mooney, J1
Watts, RA1

Reviews

1 review available for fluorouracil and ANCA-Associated Vasculitides

ArticleYear
ANCA vasculitis: time for a change in treatment paradigm? Not yet.
    Rheumatology (Oxford, England), 2011, Volume: 50, Issue:6

    Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Monoclonal, Murine-Derived;

2011