Page last updated: 2024-10-27

fluorouracil and ACTH-Producing Pituitary Adenoma

fluorouracil has been researched along with ACTH-Producing Pituitary Adenoma in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zacharia, BE1
Gulati, AP1
Bruce, JN2
Carminucci, AS1
Wardlaw, SL1
Siegelin, M1
Remotti, H1
Lignelli, A1
Fine, RL2
Thearle, MS1
Freda, PU1
Isaacson, SR1
Lee, Y1

Other Studies

2 other studies available for fluorouracil and ACTH-Producing Pituitary Adenoma

ArticleYear
High response rates and prolonged survival in patients with corticotroph pituitary tumors and refractory Cushing disease from capecitabine and temozolomide (CAPTEM): a case series.
    Neurosurgery, 2014, Volume: 74, Issue:4

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Ca

2014
Temozolomide (Temodar®) and capecitabine (Xeloda®) treatment of an aggressive corticotroph pituitary tumor.
    Pituitary, 2011, Volume: 14, Issue:4

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Combined Chemotherapy Protocols; Capecitab

2011