fluorouracil has been researched along with (pPNET) Peripheral Primitive Neuroectodermal Tumors in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiden, PL | 1 |
| Yarington, CT | 1 |
| Richardson, RG | 1 |
| Polonowski, JM | 1 |
| Brasnu, D | 1 |
| Roux, FX | 1 |
| Bassot, V | 1 |
| Heros, DO | 1 |
| Hochberg, FH | 1 |
3 other studies available for fluorouracil and (pPNET) Peripheral Primitive Neuroectodermal Tumors
| Article | Year |
|---|---|
Olfactory neuroblastoma. Chemotherapy and radiotherapy for extensive disease.
Topics: Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Middle Aged; Nasopharyngeal Neop | 1984 |
Esthesioneuroblastoma. Complete tumor response after induction chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil; Humans; Inf | 1990 |
Treatment of esthesioneuroblastoma with chemotherapy: a report of two cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male | 1988 |