Page last updated: 2024-08-26

fluoromisonidazole and Cancer of Head

fluoromisonidazole has been researched along with Cancer of Head in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's19 (28.79)29.6817
2010's42 (63.64)24.3611
2020's5 (7.58)2.80

Authors

AuthorsStudies
Alber, M; Belka, C; La Fougère, C; Nikolaou, K; Paulsen, F; Pfannenberg, C; Reimold, M; Reischl, G; Thorwarth, D; Welz, S; Zips, D1
Boeke, S; Bowden, G; Cotton, J; Krueger, MA; Leibfarth, S; Pichler, BJ; Thorwarth, D; Winter, RM; Zips, D1
Bak, B; Cegła, P; Cholewinski, W; Kazmierska, J; Malicki, J; Piotrowski, T; Sowinska, A1
Baltas, D; Bunea, H; Grosu, AL; Lazzeroni, M; Mix, M; Schiavo, F; Sörensen, A; Stoykow, C; Thomann, B; Toma-Dasu, I; Ureba, A; Wiedenmann, N1
Baumann, M; Boeke, S; Gregoire, V; Hofheinz, F; Johansen, J; Krause, M; Löck, S; Mönnich, D; Overgaard, J; Saksø Mortensen, L; Saksø, M; Seidlitz, A; Skripcak, T; Troost, EGC; Zips, D; Zöphel, K; Zschaeck, S1
Fougère, C; Leibfarth, S; Nikolaou, K; Pfannenberg, C; Reischl, G; Schmidt, H; Schwenzer, N; Simoncic, U; Thorwarth, D; Welz, S; Zips, D1
Beattie, BJ; Carlin, SD; Grkovski, M; Humm, JL; Lee, NY; Leeman, JE; O'Donoghue, JA; Riaz, N; Schöder, H2
Bandurska-Luque, A; Baumann, M; Kotzerke, J; Krause, M; Löck, S; Perrin, R; Seidlitz, A; Steinbach, J; Troost, EGC; Zips, D; Zöphel, K; Zschaeck, S1
Apte, A; Crispin-Ortuzar, M; Deasy, JO; Grkovski, M; Humm, JL; Lee, NY; Oh, JH; Schöder, H1
Agarwal, J; Budrukkar, A; Chatterjee, A; Ghosh-Laskar, S; Gupta, T; Kunder, S; Murthy, V; Purandare, N; Rangarajan, V1
Baltas, D; Bunea, H; Dasu, A; Grosu, AL; Lazzeroni, M; Toma-Dasu, I1
Abolmaali, N; Appold, S; Bandurska-Luque, A; Baumann, M; Haase, R; Kotzerke, J; Krause, M; Löck, S; Richter, C; Seidlitz, A; Steinbach, J; Troost, EGC; Zips, D; Zöphel, K1
Gafita, A; Hirata, K; Kroenke, M; Kuge, Y; Magota, K; Okamoto, S; Shiga, T; Tamaki, N; Watanabe, S1
Cegla, P; Joanna, K; Julian, M; Michal, S; Sebastian, G; Witold, C1
Aust, DE; Bandurska-Luque, A; Baretton, GB; Baumann, M; Buchholz, F; Gudziol, V; Kotzerke, J; Krause, M; Linge, A; Löck, S; Nowak, A; Overgaard, J; Seidlitz, A; Steinbach, J; Troost, EGC; Zips, D; Zöphel, K1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Mix, M; Weber, WA; Wiedenmann, N1
Alber, M; Kaanders, JH; Mönnich, D; Oyen, WJ; Thorwarth, D; Troost, EG; Zips, D1
Haba, R; Hoshikawa, H; Iwasaki, A; Kudomi, N; Maeda, Y; Matsunaga, T; Nishiyama, Y; Norikane, T; Yamamoto, Y1
de Clermont-Gallerande, H; Fernandez, P; Hatt, M; Henriques de Figueiredo, B; Lamare, F; Merlin, T; Vimont, D1
Astner, ST; Bayer, C; Cheng, X; Maftei, CA; Shi, K; Vaupel, P; Ziegler, SI1
Baumann, M; Bergmann, R; Beuthien-Baumann, B; Brüchner, K; Hessel, F; Kotzerke, J; Krause, M; Mosch, B; Schütze, C; Steinbach, J; Thames, H; Yaromina, A; Zips, D1
Giraud, P; Servagi-Vernat, S1
Fatema, CN; Kitagawa, Y; Kuge, Y; Nishijima, K; Tamaki, N; Yasuda, K; Yu, W; Zhao, S; Zhao, Y1
Galoforo, S; Grills, IS; Kane, JL; Krueger, SA; Marples, B; Wilson, GD; Wobb, J1
Abolmaali, N; Appold, S; Baumann, M; Gudziol, V; Haase, R; Kotzerke, J; Krause, M; Perrin, R; Richter, C; Steinbach, J; Stützer, K; Zips, D; Zöphel, K; Zschaeck, S1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Mix, M; Nestle, U; Pfeiffer, J; Vach, W; Weber, WA; Wiedenmann, NE1
la Fougère, C; Mauz, PS; Mönnich, D; Nikolaou, K; Pfannenberg, C; Reischl, G; Thorwarth, D; Welz, S; Zips, D1
Hirata, K; Tamaki, N1
Carlin, SD; Gönen, M; Grkovski, M; Humm, JL; Lee, NY; Nehmeh, SA; Schöder, H; Schwartz, J; Zanzonico, PB1
Hirata, K; Kasai, K; Kuge, Y; Magota, K; Nishijima, KI; Okamoto, S; Onimaru, R; Shiga, T; Shirato, H; Tamaki, N; Tuchiya, K; Watanabe, S; Yasuda, K1
Baumann, M; Mönnich, D; Thorwarth, D; Wack, LJ; Yaromina, A; Zips, D1
Bittner, MI; Bucher, S; Grosu, AL; Hentschel, M; Kayser, G; Meyer, PT; Mix, M; Rücker, G; Weber, WA; Werner, M; Wiedenmann, N1
Astner, ST; Bayer, C; Gaertner, FC; Nüsslin, F; Shi, K; Vaupel, P; Wilkens, JJ; Ziegler, SI1
Krohn, KA; Yeuh, B1
Fury, MG; Humm, JL; Jansen, JF; Koutcher, JA; Lee, NY; Pfister, DG; Schöder, H; Shukla-Dave, A; Stambuk, HE; Wang, Y1
Humm, JL; Ling, CC; Nehmeh, SA; Wang, K; Yorke, E1
Georgi, JC; Guillem, J; Humm, JL; Lee, NY; Narayanan, M; Schöder, H; Wang, W1
Kikuchi, M; Senda, M; Shinohara, S; Yamane, T1
Bentzen, L; Buus, S; Keiding, S; Mortensen, LS; Munk, OL; Nordsmark, M; Overgaard, J1
Abolmaali, N; Baumann, M; Haase, R; Koch, A; Kotzerke, J; Steinbach, J; Zips, D; Zöphel, K1
Fujiwara, K; Hori, SY; Kikuchi, M; Naito, Y; Senda, M; Shinohara, S; Tona, Y; Yamane, T; Yamazaki, H1
Bentzen, SM; Bowen, SR; Jeraj, R; Nordsmark, M; van der Kogel, AJ1
Hendrickson, K; Krohn, K; Peterson, L; Phillips, M; Rajendran, J; Smith, W1
Chen, L; Guan, Y; Kolb, HC; Walsh, JC; Zhang, J; Zhang, Z1
Abolmaali, N; Abramyuk, A; Appold, S; Baumann, M; Haase, R; Kotzerke, J; Perrin, R; Steinbach, J; Zips, D; Zöphel, K1
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J1
Anderson, NJ; Chang, JH; Gan, HK; Gong, SJ; Gunawardana, DH; Khoo, V; Lee, ST; Lim Joon, D; O'Keefe, G; Sachinidis, J; Scott, AM; Wada, M1
Ito, YM; Kasai, K; Kuge, Y; Magota, K; Okamoto, S; Shiga, T; Shirato, H; Tamaki, N; Yasuda, K1
Büll, U; Coenen, HH; Dimartino, E; Eble, MJ; Gagel, B; Hamacher, K; Maneschi, P; Pinkawa, M; Reinartz, P; Stanzel, S; Westhofen, M; Zimny, M1
Bares, R; Dittmann, H; Eschmann, SM; Machulla, HJ; Paulsen, F; Reimold, M; Reischl, G; Welz, S1
Alber, M; Eschmann, SM; Paulsen, F; Thorwarth, D3
Alber, M; Eschmann, SM; Paulsen, F; Scheiderbauer, J; Thorwarth, D1
Buell, U; Coenen, HH; DiMartino, E; Eble, M; Gagel, B; Hamacher, K; Reinartz, P; Westhofen, M; Zimny, M1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, M; Troost, EG; van der Kogel, AJ1
Alber, M; Eschmann, SM; Holzner, F; Paulsen, F; Thorwarth, D1
Grierson, JR; Krohn, KA; Ng, P; O'Sullivan, J; Peterson, LM; Rajendran, JG; Scharnhorst, J; Schwartz, DL1
Asadpour, B; Coenen, HH; Demirel, C; DiMartino, E; Eble, MJ; Gagel, B; Hamacher, K; Kaiser, HJ; Maneschi, P; Pinkawa, M; Piroth, M; Reinartz, P; Scholbach, T; Stanzel, S; Zimny, M1
Cai, S; Chan, K; Greco, C; Humm, JL; Lee, NY; Lin, Z; Ling, CC; Mechalakos, JG; Nehmeh, S; Schöder, H; Squire, OD; Zanzonico, PB1
Lee, ST; Scott, AM1
Erdi, YE; Greco, C; Humm, JL; Larson, SM; Lee, NY; Ling, CC; Mageras, G; Nehmeh, SA; Pham, HS; Schröder, H; Squire, O; Zanzonico, PB1
Humm, J; Lee, N; Lin, Z; Ling, CC; Mechalakos, J; Nehmeh, S; Schoder, H1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Lok, J; Oyen, WJ; Philippens, ME; Troost, EG; van der Kogel, AJ1
D'Costa, I; Fisher, R; Hart, R; Hicks, R; Hughes, P; Peters, L; Rischin, D; Sexton, M; von Roemeling, R1

Reviews

6 review(s) available for fluoromisonidazole and Cancer of Head

ArticleYear
Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020, Volume: 149

    Topics: Cell Hypoxia; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals

2020
[Metabolic tailoring in radiotherapy for head and neck cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden

2014
Tumor hypoxia: a new PET imaging biomarker in clinical oncology.
    International journal of clinical oncology, 2016, Volume: 21, Issue:4

    Topics: Biomarkers; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Misonidazole; Positron-Emission Tomography; Radiation Tolerance; Radiopharmaceuticals; Tumor Hypoxia

2016
Novel imaging approaches to head and neck cancer.
    Seminars in oncology, 2008, Volume: 35, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Diagnostic Imaging; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Oxygen; Positron-Emission Tomography

2008
Alternative PET tracers in head and neck cancer. A review.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10

    Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals

2013
Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole.
    Seminars in nuclear medicine, 2007, Volume: 37, Issue:6

    Topics: Animals; Brain Ischemia; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Misonidazole; Myocardial Ischemia; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Stroke

2007

Trials

12 trial(s) available for fluoromisonidazole and Cancer of Head

ArticleYear
Dose escalation to hypoxic subvolumes in head and neck cancer: A randomized phase II study using dynamic [
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 171

    Topics: Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals

2022
Monitoring early response to chemoradiotherapy with
    European journal of nuclear medicine and molecular imaging, 2017, Volume: 44, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Time Factors; Tissue Distribution; Treatment Outcome

2017
Potential of [18F]-fluoromisonidazole positron-emission tomography for radiotherapy planning in head and neck squamous cell carcinomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:12

    Topics: Aged; Carcinoma, Squamous Cell; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Reproducibility of Results; Sensitivity and Specificity; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Burden

2013
Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Conformal; Radiotherapy, Intensity-Modulated; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Serial [18F]-fluoromisonidazole PET during radiochemotherapy for locally advanced head and neck cancer and its correlation with outcome.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Chemoradiotherapy; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Kaplan-Meier Estimate; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Treatment Outcome; Tumor Burden

2015
Robustness of quantitative hypoxia PET image analysis for predicting local tumor control.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multicenter Studies as Topic; Positron-Emission Tomography; Radiopharmaceuticals; ROC Curve; Squamous Cell Carcinoma of Head and Neck

2015
The reoxygenation of hypoxia and the reduction of glucose metabolism in head and neck cancer by fractionated radiotherapy with intensity-modulated radiation therapy.
    European journal of nuclear medicine and molecular imaging, 2016, Volume: 43, Issue:12

    Topics: Adult; Aged; Dose Fractionation, Radiation; Down-Regulation; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Conformal; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Tumor Hypoxia

2016
Reduction of [(18)F]fluoromisonidazole uptake after neoadjuvant chemotherapy for head and neck squamous cell carcinoma.
    Molecular imaging and biology, 2011, Volume: 13, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Misonidazole; Neoadjuvant Therapy; Positron-Emission Tomography; Treatment Outcome

2011
pO(2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [(18)F]-2-fluoro-2'-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2004, Volume: 180, Issue:10

    Topics: Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Male; Misonidazole; Oximetry; Oxygen; Oxygen Consumption; Polarography; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2004
Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:2

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Fluorine Radioisotopes; Germany; Head and Neck Neoplasms; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Misonidazole; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome

2005
A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia.
    Physics in medicine and biology, 2005, May-21, Volume: 50, Issue:10

    Topics: Cell Hypoxia; Computer Simulation; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Kinetics; Misonidazole; Models, Biological; Neovascularization, Pathologic; Oxygen; Oxygen Consumption; Radioisotope Dilution Technique; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2005
Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jan-15, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Hypoxia; Cisplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Administration Schedule; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Radiation-Sensitizing Agents; Radiopharmaceuticals; Survival Analysis; Tirapazamine; Tomography, Emission-Computed; Triazines

2001

Other Studies

48 other study(ies) available for fluoromisonidazole and Cancer of Head

ArticleYear
Machine learning identifies multi-parametric functional PET/MR imaging cluster to predict radiation resistance in preclinical head and neck cancer models.
    European journal of nuclear medicine and molecular imaging, 2023, Volume: 50, Issue:10

    Topics: Animals; Diffusion Magnetic Resonance Imaging; Head and Neck Neoplasms; Humans; Hypoxia; Magnetic Resonance Imaging; Mice; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals

2023
Assessment of tumour hypoxia, proliferation and glucose metabolism in head and neck cancer before and during treatment.
    The British journal of radiology, 2020, Feb-01, Volume: 93, Issue:1106

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Chemoradiotherapy; Cisplatin; Dideoxynucleosides; Disease-Free Survival; Drug Administration Schedule; Feasibility Studies; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Prospective Studies; Radiation-Sensitizing Agents; Treatment Outcome; Tumor Hypoxia

2020
Quantification of Tumor Oxygenation Based on FMISO PET: Influence of Location and Oxygen Level of the Well-Oxygenated Reference Region.
    Advances in experimental medicine and biology, 2020, Volume: 1232

    Topics: Head and Neck Neoplasms; Humans; Misonidazole; Oximetry; Oxygen; Positron-Emission Tomography; Tumor Hypoxia; Tumor Microenvironment

2020
Comparison of DCE-MRI kinetic parameters and FMISO-PET uptake parameters in head and neck cancer patients.
    Medical physics, 2017, Volume: 44, Issue:6

    Topics: Contrast Media; Head and Neck Neoplasms; Humans; Kinetics; Magnetic Resonance Imaging; Misonidazole; Positron-Emission Tomography

2017
Residual tumour hypoxia in head-and-neck cancer patients undergoing primary radiochemotherapy, final results of a prospective trial on repeat FMISO-PET imaging.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 124, Issue:3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2017
Predicting hypoxia status using a combination of contrast-enhanced computed tomography and [
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:1

    Topics: Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Tumor Hypoxia

2018
Optimal timing of fluorine-18-fluoromisonidazole positron emission tomography/computed tomography for assessment of tumor hypoxia in patients with head and neck squamous cell carcinoma.
    Nuclear medicine communications, 2018, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Time Factors; Tumor Hypoxia; Young Adult

2018
Mathematical Description of Changes in Tumour Oxygenation from Repeated Functional Imaging.
    Advances in experimental medicine and biology, 2018, Volume: 1072

    Topics: Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Misonidazole; Models, Theoretical; Positron-Emission Tomography; Tumor Hypoxia

2018
FMISO-PET-based lymph node hypoxia adds to the prognostic value of tumor only hypoxia in HNSCC patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019, Volume: 130

    Topics: Adult; Aged; Cell Hypoxia; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Prognosis; Squamous Cell Carcinoma of Head and Neck; Tumor Hypoxia

2019
Voxel based comparison and texture analysis of 18F-FDG and 18F-FMISO PET of patients with head-and-neck cancer.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Predictive Value of Tests; Prognosis; Radiation Tolerance; Radiopharmaceuticals; Tumor Hypoxia

2019
Correlation between tumour biology status measured in triple-tracer 18F-fluorodeoxyglucose-18F-fluorothymidine- 18F-fluoromisonidazole-PET/CT study and human papillomavirus status in patients with head and neck cancer.
    Nuclear medicine communications, 2019, Volume: 40, Issue:7

    Topics: Aged; Aged, 80 and over; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Papillomaviridae; Positron Emission Tomography Computed Tomography; Radioactive Tracers

2019
Repeat FMISO-PET imaging weakly correlates with hypoxia-associated gene expressions for locally advanced HNSCC treated by primary radiochemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019, Volume: 135

    Topics: Adult; Aged; Cell Hypoxia; Cohort Studies; Female; Fluorine Radioisotopes; Gene Expression; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2019
Exploratory geographical analysis of hypoxic subvolumes using 18F-MISO-PET imaging in patients with head and neck cancer in the course of primary chemoradiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:3

    Topics: Cell Hypoxia; Chemoradiotherapy; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Male; Misonidazole; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals

2013
Correlation between tumor oxygenation and 18F-fluoromisonidazole PET data simulated based on microvessel images.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Computer Simulation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Mice; Microvessels; Misonidazole; Oxygen; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tumor Cells, Cultured

2013
Correlation of (18)F-fluoromisonidazole PET findings with HIF-1α and p53 expressions in head and neck cancer: comparison with (18)F-FDG PET.
    Nuclear medicine communications, 2014, Volume: 35, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Female; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Tumor Suppressor Protein p53

2014
Preclinical evaluation of parametric image reconstruction of [18F]FMISO PET: correlation with ex vivo immunohistochemistry.
    Physics in medicine and biology, 2014, Jan-20, Volume: 59, Issue:2

    Topics: Animals; Cell Line, Tumor; Female; Head and Neck Neoplasms; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Misonidazole; Positron-Emission Tomography

2014
Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 111, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Radiation; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Random Allocation; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays

2014
Dual tracer evaluation of dynamic changes in intratumoral hypoxic and proliferative states after radiotherapy of human head and neck cancer xenografts using radiolabeled FMISO and FLT.
    BMC cancer, 2014, Sep-22, Volume: 14

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Head and Neck Neoplasms; Heterografts; Humans; Hypoxia; Male; Mice; Misonidazole; Radionuclide Imaging; Radiopharmaceuticals; Tumor Burden

2014
The Effects of Pulsed Radiation Therapy on Tumor Oxygenation in 2 Murine Models of Head and Neck Squamous Cell Carcinoma.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Coloring Agents; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Heterografts; Mice; Mice, Nude; Misonidazole; Neoplasm Recurrence, Local; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tumor Burden

2015
Feasibility of 18F-Fluoromisonidazole Kinetic Modeling in Head and Neck Cancer Using Shortened Acquisition Times.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:3

    Topics: Algorithms; Animals; Carcinoma, Squamous Cell; Cohort Studies; Colorectal Neoplasms; Head and Neck Neoplasms; HT29 Cells; Humans; Hypoxia; Image Processing, Computer-Assisted; Misonidazole; Neoplasm Transplantation; Perfusion; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reproducibility of Results; Retrospective Studies; ROC Curve

2016
Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O2 consumption?
    Medical physics, 2016, Volume: 43, Issue:7

    Topics: Animals; Benzimidazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Computer Simulation; Feasibility Studies; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Hypoxia; Mice, Nude; Misonidazole; Models, Biological; Neoplasm Transplantation; Nitroimidazoles; Oxygen Consumption; Platelet Endothelial Cell Adhesion Molecule-1; Tumor Microenvironment

2016
Analysis of relation between hypoxia PET imaging and tissue-based biomarkers during head and neck radiochemotherapy.
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:11

    Topics: Adult; Aged; Biomarkers, Tumor; Carbonic Anhydrase IX; Carcinoma, Squamous Cell; Chemoradiotherapy; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Immunohistochemistry; Ku Autoantigen; Male; Middle Aged; Misonidazole; Papillomavirus Infections; Positron-Emission Tomography; Proportional Hazards Models; Radiopharmaceuticals; Tomography, X-Ray Computed; Tumor Hypoxia

2016
Matching the reaction-diffusion simulation to dynamic [
    Physiological measurement, 2017, Volume: 38, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Diffusion; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Mice; Mice, Nude; Misonidazole; Models, Biological; Neoplasms, Squamous Cell; Oxygen; Positron-Emission Tomography; Tumor Hypoxia; Tumor Microenvironment

2017
Multiparametric Imaging of Tumor Hypoxia and Perfusion with
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017, Volume: 58, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Misonidazole; Multimodal Imaging; Neovascularization, Pathologic; Observer Variation; Oxygen; Perfusion Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Tumor Hypoxia

2017
Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.
    International journal of radiation oncology, biology, physics, 2010, Aug-01, Volume: 77, Issue:5

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Retrospective Studies; Statistics, Nonparametric

2010
Modeling acute and chronic hypoxia using serial images of 18F-FMISO PET.
    Medical physics, 2009, Volume: 36, Issue:10

    Topics: Acute Disease; Algorithms; Cell Hypoxia; Chronic Disease; Computer Simulation; Head and Neck Neoplasms; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Misonidazole; Models, Biological; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique

2009
Pharmacokinetic analysis of hypoxia (18)F-fluoromisonidazole dynamic PET in head and neck cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:1

    Topics: Aged; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Neoplasm Staging; Plasma; Positron-Emission Tomography; Radiopharmaceuticals; Regional Blood Flow

2010
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Biosensing Techniques; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Hypoxia; Microchemistry; Microelectrodes; Misonidazole; Neoplasms; Oxygen; Positron-Emission Tomography; Sarcoma; Soft Tissue Neoplasms

2010
Two or four hour [¹⁸F]FMISO-PET in HNSCC. When is the contrast best?
    Nuklearmedizin. Nuclear medicine, 2011, Volume: 50, Issue:1

    Topics: Carcinoma, Small Cell; Female; Head and Neck Neoplasms; Humans; Image Enhancement; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Time Factors

2011
18F-fluoromisonidazole positron emission tomography before treatment is a predictor of radiotherapy outcome and survival prognosis in patients with head and neck squamous cell carcinoma.
    Annals of nuclear medicine, 2011, Volume: 25, Issue:9

    Topics: Adult; Aged; Analysis of Variance; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multimodal Imaging; Positron-Emission Tomography; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome

2011
Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modeling.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:6

    Topics: Biological Transport; Cell Hypoxia; Coordination Complexes; Copper Radioisotopes; Electrochemistry; Head and Neck Neoplasms; Humans; Misonidazole; Models, Biological; Organometallic Compounds; Oxygen; Positron-Emission Tomography; Radioactive Tracers; Reproducibility of Results; Thiosemicarbazones; Time Factors

2011
Hypoxia imaging with [F-18] FMISO-PET in head and neck cancer: potential for guiding intensity modulated radiation therapy in overcoming hypoxia-induced treatment resistance.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 101, Issue:3

    Topics: Cell Hypoxia; Head and Neck Neoplasms; Humans; Misonidazole; Positron-Emission Tomography; Radiation Tolerance; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Radiotherapy, Intensity-Modulated

2011
¹⁸F-HX4 hypoxia imaging with PET/CT in head and neck cancer: a comparison with ¹⁸F-FMISO.
    Nuclear medicine communications, 2012, Volume: 33, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cell Hypoxia; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Tomography, X-Ray Computed; Triazoles

2012
Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1

    Topics: Aged; Cell Hypoxia; Chemoradiotherapy; Disease-Free Survival; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prognosis; Proportional Hazards Models; Prospective Studies

2012
Hypoxia-targeted radiotherapy dose painting for head and neck cancer using (18)F-FMISO PET: a biological modeling study.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:8

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Cohort Studies; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Models, Biological; Neoplasm Staging; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated

2013
High reproducibility of tumor hypoxia evaluated by 18F-fluoromisonidazole PET for head and neck cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:2

    Topics: Adult; Aged; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Male; Middle Aged; Misonidazole; Nuclear Medicine; Positron-Emission Tomography; Prognosis; Radiation Oncology; Radiopharmaceuticals; Reproducibility of Results; Time Factors

2013
Kinetic analysis of dynamic 18F-fluoromisonidazole PET correlates with radiation treatment outcome in head-and-neck cancer.
    BMC cancer, 2005, Dec-01, Volume: 5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Head and Neck Neoplasms; Humans; Hypoxia; Image Processing, Computer-Assisted; Kinetics; Male; Middle Aged; Misonidazole; Models, Statistical; Positron-Emission Tomography; Radiation-Sensitizing Agents; Software; Treatment Outcome

2005
FDG--a marker of tumour hypoxia? A comparison with [18F]fluoromisonidazole and pO2-polarography in metastatic head and neck cancer.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:12

    Topics: Biomarkers, Tumor; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypoxia; Misonidazole; Neoplasm Metastasis; Oxygen; Polarography; Positron-Emission Tomography; Reference Standards

2006
Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorine Radioisotopes; Glioblastoma; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Radionuclide Imaging

2006
Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 80, Issue:2

    Topics: Aged; Cell Hypoxia; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome

2006
Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Sep-15, Volume: 12, Issue:18

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Follow-Up Studies; Head and Neck Neoplasms; Humans; Middle Aged; Misonidazole; Multivariate Analysis; Positron-Emission Tomography; Survival Analysis

2006
A model of reoxygenation dynamics of head-and-neck tumors based on serial 18F-fluoromisonidazole positron emission tomography investigations.
    International journal of radiation oncology, biology, physics, 2007, Jun-01, Volume: 68, Issue:2

    Topics: Algorithms; Cell Hypoxia; Head and Neck Neoplasms; Humans; Misonidazole; Models, Biological; Oxygen; Positron-Emission Tomography; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tumor Burden

2007
Hypoxia dose painting by numbers: a planning study.
    International journal of radiation oncology, biology, physics, 2007, May-01, Volume: 68, Issue:1

    Topics: Cell Hypoxia; Feasibility Studies; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated

2007
pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle o
    BMC cancer, 2007, Jun-28, Volume: 7

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Misonidazole; Oxygen Consumption; Polarography; Positron-Emission Tomography; Prognosis; Ultrasonography, Doppler, Color

2007
Fluorine-18-labeled fluoromisonidazole positron emission and computed tomography-guided intensity-modulated radiotherapy for head and neck cancer: a feasibility study.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Cell Hypoxia; Feasibility Studies; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Prospective Studies; Radiation-Sensitizing Agents; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed

2008
Reproducibility of intratumor distribution of (18)F-fluoromisonidazole in head and neck cancer.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Aged; Cell Hypoxia; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Misonidazole; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Reproducibility of Results; Tomography, X-Ray Computed

2008
The influence of changes in tumor hypoxia on dose-painting treatment plans based on 18F-FMISO positron emission tomography.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Cell Hypoxia; Feasibility Studies; Follow-Up Studies; Head and Neck Neoplasms; Humans; Misonidazole; Positron-Emission Tomography; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated

2008
Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:10

    Topics: Animals; Autoradiography; Biomarkers, Tumor; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Misonidazole; Nitroimidazoles; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2008