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fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether and Kidney Diseases

fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether has been researched along with Kidney Diseases in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (60.00)18.2507
2000's6 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altuntas, TG; Kharasch, ED; Zager, RA1
Altuntas, TG; Kharasch, ED; Liggitt, HD; Schroeder, JL; Sheffels, P1
Kharasch, ED; Liggitt, HD; Schroeder, JL; Sheffels, P1
Bammler, T; Beyer, R; Kharasch, ED; Schroeder, JL; Srinouanprachanh, S1
Eger, EI; Kandel, L; Kerschmann, RL; Laster, MJ; Martin, J1
Eger, EI; Ferrell, LD; Gonsowski, CT; Kerschmann, RL; Laster, MJ2
Callan, C; Cusick, PK; Delgado-Herrera, L; Friedman, MB; Hoffman, GM; Keller, KA; Krasula, RW; Prokocimer, P; Wooding, WL1
Eger, EI; Kandel, L; Kerschmann, RL; Laster, MJ; Martin, JL; Reed, GF1
Bowland, T; Eger, EI; Gong, D; Ionescu, P; Koblin, DD; Laster, MJ; Weiskopf, RB1
Eger, EI; Gong, D; Ionescu, P; Kerschmann, RL; Laster, MJ; Weiskopf, RB1
Ebert, TJ; Frink, EJ; Kharasch, ED1
Anders, MW; Baggs, RB; Iyer, RA; Uttamsingh, V1
Eger, EI1
Gentz, BA; Malan, TP1

Reviews

1 review(s) available for fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether and Kidney Diseases

ArticleYear
Renal toxicity with sevoflurane: a storm in a teacup?
    Drugs, 2001, Volume: 61, Issue:15

    Topics: Air Movements; Anesthetics, Inhalation; Drug Interactions; Ethers; Gases; Humans; Hydrocarbons, Fluorinated; Kidney; Kidney Diseases; Methyl Ethers; Sevoflurane

2001

Other Studies

14 other study(ies) available for fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether and Kidney Diseases

ArticleYear
Cytotoxicity of S-conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl) vinyl ether (Compound A) in a human proximal tubular cell line.
    Toxicology and applied pharmacology, 2003, Nov-15, Volume: 193, Issue:1

    Topics: Anesthetics, Inhalation; Cell Line; Cysteine; Ethers; Formazans; Glutathione; Humans; Hydrocarbons, Fluorinated; Kidney Diseases; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Methyl Ethers; Sevoflurane; Tetrazolium Salts

2003
Role of cytochrome P4503A in cysteine S-conjugates sulfoxidation and the nephrotoxicity of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in rats.
    Chemical research in toxicology, 2004, Volume: 17, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Aryl Hydrocarbon Hydroxylases; Cysteine; Cytochrome P-450 CYP3A; Dexamethasone; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Lyases; Male; Methyl Ethers; Oxidoreductases, N-Demethylating; Phenobarbital; Propionates; Rats; Rats, Inbred F344; Sevoflurane; Sulfoxides; Troleandomycin

2004
Influence of sevoflurane on the metabolism and renal effects of compound A in rats.
    Anesthesiology, 2005, Volume: 103, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Biotransformation; Ethers; Hydrocarbons, Fluorinated; Kidney; Kidney Diseases; Kidney Function Tests; Male; Methyl Ethers; Rats; Rats, Inbred F344; Sevoflurane; Sulfoxides

2005
Gene expression profiling of nephrotoxicity from the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether ("compound A") in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Ethers; Gene Expression Profiling; Hydrocarbons, Fluorinated; Kidney; Kidney Diseases; Male; Methyl Ethers; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sevoflurane

2006
Nephrotoxicity in rats undergoing a one-hour exposure to compound A.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:3

    Topics: Animals; Cell Division; Cell Nucleus; Dose-Response Relationship, Drug; Ethers; Hydrocarbons, Fluorinated; Immunohistochemistry; Kidney Diseases; Liver; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Vinyl Compounds

1995
Toxicity of compound A in rats. Effect of increasing duration of administration.
    Anesthesiology, 1994, Volume: 80, Issue:3

    Topics: Anesthetics; Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethers; Hydrocarbons, Fluorinated; Immunohistochemistry; Kidney Diseases; Lethal Dose 50; Lung Diseases; Male; Methyl Ethers; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Pulmonary Edema; Rats; Rats, Wistar; Regeneration; Sevoflurane; Time Factors

1994
Toxicity of compound A in rats. Effect of a 3-hour administration.
    Anesthesiology, 1994, Volume: 80, Issue:3

    Topics: Anesthetics; Animals; Brain; Brain Diseases; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Lethal Dose 50; Male; Methyl Ethers; Rats; Rats, Wistar; Sevoflurane; Time Factors

1994
Inhalation toxicity study of a haloalkene degradant of sevoflurane, Compound A (PIFE), in Sprague-Dawley rats.
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Chemical Analysis; Blood Coagulation; Dose-Response Relationship, Drug; Ethers; Female; Hydrocarbons, Fluorinated; Kidney Diseases; Male; Methyl Ethers; Nasal Mucosa; Rats; Rats, Sprague-Dawley; Sevoflurane

1995
Metabolism of compound A by renal cysteine-S-conjugate beta-lyase is not the mechanism of compound A-induced renal injury in the rat.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:4

    Topics: Aminooxyacetic Acid; Anesthetics, Inhalation; Animals; Buthionine Sulfoximine; Carbon-Sulfur Lyases; Enzyme Inhibitors; Ethers; Glutathione; Hydrocarbons, Fluorinated; Isoxazoles; Kidney; Kidney Diseases; Lyases; Male; Methionine Sulfoximine; Methyl Ethers; Rats; Rats, Wistar; Sevoflurane

1996
Dose-related biochemical markers of renal injury after sevoflurane versus desflurane anesthesia in volunteers.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Biomarkers; Chemical and Drug Induced Liver Injury; Desflurane; Dose-Response Relationship, Drug; Ethers; Fluorides; Humans; Hydrocarbons, Fluorinated; Isoflurane; Kidney Diseases; Kidney Glomerulus; Liver Diseases; Male; Methyl Ethers; Sevoflurane; Temperature; Tidal Volume

1997
Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Absorption; Aminooxyacetic Acid; Anesthetics, Inhalation; Animals; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Ethers; Halothane; Humans; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Isoxazoles; Kidney Diseases; Lyases; Methyl Ethers; Rats; Rats, Inbred F344; Rats, Wistar; Sevoflurane

1997
Absence of biochemical evidence for renal and hepatic dysfunction after 8 hours of 1.25 minimum alveolar concentration sevoflurane anesthesia in volunteers.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Adult; Alanine Transaminase; Anesthetics, Inhalation; Body Temperature; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Ethers; Glutathione Transferase; Glycosuria; Humans; Hydrocarbons, Fluorinated; Kidney; Kidney Diseases; Liver; Methyl Ethers; Proteinuria; Sevoflurane; Volunteers

1998
Fate and toxicity of 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived mercapturates in male, Fischer 344 rats.
    Anesthesiology, 1998, Volume: 89, Issue:5

    Topics: Acetylcysteine; Acyltransferases; Anesthetics, Inhalation; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cytosol; Dealkylation; Drug Contamination; Ethers; Hydrocarbons, Fluorinated; Kidney Diseases; Magnetic Resonance Spectroscopy; Male; Methyl Ethers; Rats; Rats, Inbred F344; Sevoflurane

1998
Compound A: does it matter?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:5

    Topics: Adsorption; Anesthetics, Inhalation; Canada; Carbon Dioxide; Ethers; Humans; Hydrocarbons, Fluorinated; Kidney Diseases; Methyl Ethers; Sevoflurane

2001