fluorodopa f 18 has been researched along with Idiopathic Parkinson Disease in 205 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (1.95) | 18.7374 |
| 1990's | 65 (31.71) | 18.2507 |
| 2000's | 85 (41.46) | 29.6817 |
| 2010's | 37 (18.05) | 24.3611 |
| 2020's | 14 (6.83) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YC; Li, D; Li, R; Shang, S; Tian, Y; Yin, X; Zhang, Y; Zhao, H; Zheng, L | 1 |
| Chen, YC; Huang, T; Jiang, T; Tian, YY; Wang, F; Wang, SY; Zhang, YD; Zhou, LL | 1 |
| Albillo, D; Blesa, J; Del Álamo, M; Duque, A; Fernández-Rodríguez, B; Foffani, G; Gasca-Salas, C; Guida, P; Hernández-Fernández, F; Martínez-Fernández, R; Mata-Marín, D; Matarazzo, M; Montero, JI; Obeso, I; Obeso, JA; Pineda-Pardo, JA; Plaza de Las Heras, I; Rachmilevitch, I; Rodríguez-Rojas, R; Toltsis, G; Trompeta, C | 1 |
| Chen, J; Chen, L; Chu, J; Jiang, L; Luo, G; Shi, X; Wang, J; Wu, L; Yang, Y; Yi, C; Zhang, X | 1 |
| Lawton, M; Lloyd, K; Whone, A | 1 |
| Cohn, M; Gasca-Salas, C; Guida, P; López-Aguirre, M; Mata-Marín, D; Monje, MH; Obeso, I; Pineda-Pardo, JA; Sánchez Ferro, Á; Trompeta, C | 1 |
| Beuthien-Baumann, B; Kotzerke, J; Löhle, M; Oehme, L; Reichmann, H; Storch, A; van den Hoff, J; Wolz, M | 1 |
| Chaves, LT; De Jong, BM; Dierckx, RAJO; Doorduin, J; Kremer, BPH; Leenders, KL; Stormezand, GN; Vállez García, D | 1 |
| Berman, KF; Eisenberg, DP; Gregory, MD; Groden, C; Grogans, SE; Ianni, AM; Kim, J; Lopez, G; Masdeu, JC; Sidransky, E | 1 |
| Drzezga, A; Eggers, C; Greuel, A; Hammes, J; Maier, F; Ruppert, MC; Schwartz, F; Stürmer, S; Tahmasian, M; Timmermann, L; Tittgemeyer, M; van Eimeren, T | 1 |
| Andersen, KB; Borghammer, P; Brooks, DJ; Fedorova, TD; Hansen, AK; Kinnerup, M; Knudsen, K; Nahimi, A; Pavese, N; Sommerauer, M; Van Den Berge, N; Vang, K | 1 |
| Eggers, C; Eidelberg, D; Fink, GR; Holtbernd, F; Ma, Y; Oh, A; Spetsieris, P; Tang, CC; Timmermann, L | 1 |
| Even-Sapir, E; Freedman, N; Giladi, N; Kestenbaum, M; Kuten, J; Lerman, H; Linevitz, A; Shiner, T | 1 |
| Mittal, BR; Modi, M; Shree, R; Shukla, J; Sood, A; Vatsa, R | 1 |
| Aasly, J; Adam, M; Agarwal, PA; Dinelle, K; Ding, YS; Farrer, M; Guttman, M; Hasegawa, K; Mak, E; McKenzie, J; Neilson, N; Schulzer, M; Shahinfard, E; Sossi, V; Stoessl, AJ; Strongosky, A; Uitti, RJ; Vafai, N; Wile, DJ; Wszolek, ZK; Zabetian, CP; Zhang, J | 1 |
| Goldstein, DS; Holmes, C; Lopez, GJ; Sharabi, Y; Wu, T | 1 |
| Djaldetti, R; Greenbaum, L; Lorberboym, M; Poewe, W; Rigbi, A; Roditi, Y; Scherfler, C; Steinmetz, A | 1 |
| Barclay, CL; Barua, NU; Blinder, S; Boca, M; Boiko, C; Broadfoot, J; Cronin, D; Dharia, S; Fibiger, HC; Gill, SS; Harrison, R; Howell, M; Irving, C; Johnson, D; Johnson, GA; Kinch, S; Lawrence, AD; Lewis, O; Longpre, L; Luz, M; Marshall, C; Mohr, E; Mooney, L; Pritchard, G; Schroers, C; Skinner, P; Sossi, V; Stoessl, AJ; Whone, AL; Woolley, M | 1 |
| D'Souza, MM; Jaimini, A; Mehta, S; Mishra, AK; Mondal, A; Pandey, S; Panwar, P; Saw, S; Sharma, R; Singh, D; Solanki, Y; Tripathi, M | 1 |
| Bergman, J; Brück, A; Johansson, J; Jokinen, P; Karrasch, M; Rinne, JO | 1 |
| Bendlin, BB; Buyan-Dent, L; Christian, BT; DeJesus, OT; Gallagher, CL; Harding, SJ; Holden, JE; Li, CT; Nickles, RJ; Oh, J; Okonkwo, O; Palotti, M; Stone, CK | 1 |
| Eggers, C; Kracht, L; Pedrosa, DJ; Schwartz, F; Timmermann, L | 1 |
| Bergman, J; Johansson, J; Joutsa, J; Kaasinen, V; Niemelä, S; Voon, V | 1 |
| Abbruzzese, G; Arnaldi, D; Bossert, I; Brugnolo, A; Campus, C; Castaldi, A; De Carli, F; Girtler, N; Marinelli, L; Morbelli, S; Nobili, F; Piccardo, A; Picco, A | 1 |
| de Jong, BM; Leenders, KL; Pikstra, ARA; van der Hoorn, A | 1 |
| Bhidayasiri, R; Boonla, C; Chotipanich, C; Dissayabutra, T; Joutsa, J; Kaewwilai, L; Muensri, S; Rinne, J; Tosukhowong, P | 1 |
| Hijioka, M; Inden, M; Inubushi, T; Kitamura, Y; Morikawa, S; Oda, K; Taniguchi, T; Tooyama, I; Yanagisawa, D | 1 |
| Capriati, V; Dimiccoli, V; Mandracchia, D; Maqoud, F; Mele, A; Scilimati, A; Tolomeo, A; Trapani, A; Trapani, G; Tricarico, D; Vitale, P | 1 |
| Dierckx, RA; Koole, M; Leenders, KL; Lopes Alves, I; Marques da Silva, AM; Meles, SK; Willemsen, AT | 1 |
| Bahri, MA; Becker, G; Garraux, G; Hustadt, F; Lemaire, C; Luxen, A; Michel, A; Plenevaux, A | 1 |
| Dierckx, RA; Eshuis, SA; Jager, PL; Jonkman, S; Leenders, KL; Maguire, RP | 1 |
| Brück, A; Eskola, O; Helenius, H; Jokinen, P; Rauhala, E; Rinne, JO | 1 |
| Goldstein, DS; Holmes, C; Kopin, IJ; Sewell, L | 1 |
| Cumming, P; Kumakura, Y | 1 |
| Bhatia, KP; Brooks, DJ; Cohen, L; Khan, NL; Lees, AJ; Pavese, N; Piccini, P; Quinn, NP; Scherfler, C; Wood, NW | 1 |
| Marek, K; Poewe, W; Scherfler, C; Tolosa, E | 1 |
| Bartenstein, P; Buchholz, HG; Cumming, P; Danielsen, EH; Gjedde, A; Gründer, G; Heinz, A; Kumakura, Y; Vernaleken, I | 1 |
| Breeze, R; Chaly, T; Dhawan, V; Eidelberg, D; Fahn, S; Freed, C; Greene, P; Ma, Y; Tang, C | 1 |
| Baudrexel, S; Diederich, NJ; Eggers, C; Heiss, WD; Hilker, R; Hohmann, C; Kalbe, E; Klein, JC; Vollmar, S; Weisenbach, S | 1 |
| Bressman, S; Brüggemann, N; Condefer, K; Dhawan, V; Hagenah, J; Klein, C; Kornreich, R; Ozelius, L; Palmese, C; Pastores, G; Roe, A; Sathe, S; Saunders-Pullman, R; Stanley, K; Tagliati, M | 1 |
| Behnke, S; Berg, D; Schröder, U | 1 |
| Remy, P | 1 |
| Schwarz, J | 1 |
| Brooks, DJ; Lewis, SJ; Pavese, N; Rivero-Bosch, M; Whone, AL | 1 |
| Bendlin, BB; Brown, WD; Chung, MK; DeJesus, O; Gallagher, CL; Holden, JE; Johnson, SC; McLaren, DG; Nickles, RJ; Oakes, TR; Pyzalski, R; Xu, G | 1 |
| Martin, WR | 1 |
| Birke, AM; Criswell, SR; Flores, HP; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Beuthien-Baumann, B; Herting, B; Kotzerke, J; Langner, J; Löhle, M; Oehme, L; Perick, M; Reichmann, H; Storch, A; van den Hoff, J; Wolz, M | 1 |
| Bjorklund, A; Brooks, DJ; Lindvall, O; Oertel, WH; Piccini, P; Pogarell, O; Politis, M; Quinn, NP; Wu, K | 1 |
| Bendlin, BB; Buyan-Dent, L; Christian, BT; Dejesus, OT; Gallagher, CL; Harding, SJ; Holden, JE; Johnson, SC; Mueller, B; Nickles, RJ; Stone, CK | 1 |
| Goldstein, DS; Holmes, C; Park, MY; Sewell, L; Sharabi, Y | 1 |
| Chang, IC; Hsieh, HJ; Kao, CH; Liu, SH; Lue, KH | 1 |
| Brooks, DJ; Chaudhuri, KR; Metta, V; Pavese, N; Ramlackhansingh, A; Simpson, BS | 1 |
| Brooks, DJ; Eggert, K; Gerhard, A; Lewis, SJ; Mathias, CJ; Oertel, W; Pavese, N; Rivero-Bosch, M | 1 |
| Birke, AM; Crippin, JS; Criswell, SR; Flores, HP; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Bours, V; Caberg, JH; Dive, D; Garraux, G; Jamar, M; Moonen, G; Vanbellinghen, JF | 1 |
| Eskola, O; Jokinen, P; Joutsa, J; Kaasinen, V; Rinne, JO | 1 |
| Deuschl, G; Ghaemi, M; Heiss, WD; Hilker, R; Raethjen, J; Rudolf, J; Sobesky, J | 1 |
| Jennings, D; Marek, K; Seibyl, J | 1 |
| Bailey, DL; Brooks, DJ; Ito, K; Morrish, PK; Pavese, N; Rakshi, JS; Uema, T | 1 |
| de la Fuente-Fernandez, R; Holden, JE; Ruth, TJ; Sossi, V; Stoessl, AJ | 1 |
| Dendi, R; Goldstein, DS; Holmes, C; Li, ST; Sharabi, Y | 1 |
| Agid, Y; Brice, A; Broussolle, E; Chapoy, E; Costes, N; Dürr, A; Guillouet, S; Lohmann, E; Pollak, P; Rascol, O; Remy, P; Ribeiro, MJ; Thobois, S | 1 |
| Seibyl, JP | 1 |
| Cheng, CY; Chiang, YH; Chou, YH; Huang, WS; Lin, JC; Liu, RS | 1 |
| Piccini, P | 1 |
| Brin, MF; Freeman, TB; Godbold, J; Goetz, CG; Kordower, JH; Nauert, GM; Olanow, CW; Perl, DP; Shannon, KM; Sossi, V; Stoessl, AJ | 1 |
| Ghaemi, M; Heiss, WD; Hilker, R; Razai, N; Rudolf, J; Szelies, B; Weisenbach, S | 1 |
| Pirker, W | 1 |
| Behr, T; Bornschein, B; Dodel, RC; Höffken, H; Klockgether, T; Möller, JC; Oertel, WH; Siebert, U | 1 |
| Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ | 1 |
| Bergman, J; Eskola, O; Forsback, S; Grönroos, T; Haapalinna, A; Haaparanta, M; Marjamäki, P; Niemi, R; Rinne, J; Solin, O | 1 |
| Heiss, WD; Hilker, R | 1 |
| Antonini, A; Leenders, KL; Linazasoro, G; Maguire, RP | 1 |
| Brooks, DJ; Eunson, L; Graham, E; Khan, NL; Lees, AJ; Pavese, N; Piccini, PP; Quinn, NP; Scherfler, C; Wood, NW | 1 |
| Abe, Y; Arahata, Y; Dagher, A; Hatano, K; Ito, K; Iwai, K; Kachi, T; Kato, T; Kawasumi, Y; Nagano-Saito, A; Nakamura, A; Washimi, Y; Yamada, T | 1 |
| Bailey, DL; Brooks, DJ; Pavese, N; Remy, P; Whone, AL | 1 |
| Cumming, P; Danielsen, EH; Gjedde, A; Kumakura, Y; Reilhac, A | 1 |
| de la Fuente-Fernández, R; Holden, JE; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, J | 1 |
| Ahlskog, JE; Albin, RL; Brooks, DJ; Carbon, M; Dhawan, V; Eidelberg, D; Fahn, S; Feigin, A; Guttman, M; Gwinn-Hardy, K; Holloway, R; Innis, R; Katz, RG; Kieburtz, K; Kish, SJ; Lange, N; Langston, JW; Marek, K; McFarland, H; Morin, L; Moy, C; Murphy, D; Oertel, WH; Oliver, G; Palesch, Y; Powers, W; Ravina, B; Seibyl, J; Sethi, KD; Sheehy, P; Shults, CW; Stoessl, AJ | 1 |
| Evanoff, B; Good, L; Jennings, D; Perlmutter, JS; Racette, BA; Tabbal, SD | 1 |
| Fischman, AJ | 1 |
| Aalto, S; Bergman, J; Brück, A; Nurmi, E; Rinne, JO | 1 |
| Auburger, G; Berman, KF; Evans, EW; Hernandez, DG; Jain, S; Johnson, J; Lopez, GJ; McInerney-Leo, A; Meyer-Lindenberg, A; Nussbaum, RL; Paisán-Ruíz, C; Schäffer, AA; Singleton, AB | 1 |
| Coburger, S; Ghaemi, M; Heiss, WD; Herholz, K; Hilker, R; Jacobs, AH; Rudolf, J; Schweitzer, K; Weisenbach, S | 1 |
| Broussolle, E; Remy, P; Thobois, S | 1 |
| Christensen, S; Cumming, P; Danielsen, EH; Gjedde, A; Kumakura, Y | 1 |
| Barker, RA; Brooks, DJ; Cheesman, AL; Lewis, SJ; Owen, AM; Robbins, TW | 1 |
| Borghammer, P; Cumming, P; Kumakura, Y | 1 |
| Declerck, JM; Leong, FJ; McLaughlin, RA; Pan, XB; Silverman, DH; Wright, TG | 1 |
| Lilien, DL; Patterson, J; Tainter, K; Zweig, RM | 1 |
| Hundemer, HP; Kaasinen, V; Leenders, KL; Maguire, RP | 1 |
| Burghaus, L; Heiss, WD; Herholz, K; Hilker, R; Jacobs, AH; Kalbe, E; Klein, JC; Thomas, AV; Weisenbach, S | 1 |
| Adams, J; de la Fuente-Fernández, R; Schulzer, M; Sossi, V; Stoessl, J | 1 |
| Antenor, JA; Good, L; McGee-Minnich, L; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Aalto, S; Bergman, J; Brück, A; Nurmi, E; Rinne, JO; Vahlberg, T | 1 |
| Balash, Y; Bartels, AL; de Jong, BM; Giladi, N; Leenders, KL; Maguire, RP; Pruim, J; Schaafsma, JD; Veenma, L; Youdim, MB | 1 |
| Deleu, D; Hanssens, Y | 1 |
| Gorman, JM | 1 |
| Ametamey, SM; Blagoev, M; Hengerer, B; Hintermann, S; Honer, M; Schubiger, PA; Waldmeier, P | 1 |
| Dhawan, V; Eckert, T; Eidelberg, D; Feigin, A; Frucht, S; Lewis, DE | 1 |
| Brooks, DJ | 4 |
| Koerts, J; Koning, M; Leenders, KL; Portman, AT; van Beilen, M | 1 |
| Crews, C; Goldstein, DS; Hallett, M; Hardy, J; Holmes, C; Imrich, R; Lopez, G; Peckham, E; Singleton, A | 1 |
| Fanti, S; Nanni, C; Rubello, D | 1 |
| Kato, T | 1 |
| Brown, L; Dickson, D; Farrer, M; Skipper, L; Solida, A; Vingerhoets, FJ; Wider, C; Wszolek, ZK | 1 |
| Bara-Jimenez, W; Brown, AK; Cropley, VL; Fujita, M; Hallett, M; Herscovitch, P; Innis, RB; Nathan, PJ; Pike, VW; Sangare, J; Zhang, XY | 1 |
| Antonini, A; Günther, I; Leenders, KL; Maguire, PR; Missimer, J; Psylla, M; Vontobel, P | 1 |
| Brooks, DJ; Morrish, PK; Sawle, GV | 2 |
| Defer, G; Fénelon, G; Fontaine, A; Frouin, V; Gény, C; Hantraye, P; Mangin, JF; Remy, P; Ricolfi, F; Samson, Y | 1 |
| Brooks, DJ; Burn, DJ; Mark, MH; Menza, MA | 1 |
| Cumming, P; Diksic, M; Evans, AC; Gjedde, A; Guttman, M; Kuwabara, H; Léger, GC; Yasuhara, Y | 1 |
| Cordes, M; Poewe, W | 1 |
| Martin, WR; Perlmutter, JS | 1 |
| Chaly, T; Dhawan, V; Eidelberg, D; Fahn, S; Giladi, N; Ishikawa, T; Przedborski, S; Spetsieris, P; Takikawa, S | 1 |
| Calne, DB; Lee, CS; Mak, E; Schulzer, M; Snow, BJ; Vingerhoets, FJ | 1 |
| Brooks, DJ; Burn, DJ; Lammertsma, AA; Luthra, S; Morrish, PK; Osman, S; Sawle, GV; Snow, BJ | 1 |
| Björklund, A; Brooks, D; Brundin, P; Frackowiak, R; Lindvall, O; Marsden, CD; Odin, P; Rothwell, JC; Sawle, G; Widner, H | 1 |
| Chaly, T; Dahl, R; Dhawan, V; Eidelberg, D; Mandel, F; Robeson, W; Spetsieris, P; Takikawa, S; Zanzi, I | 1 |
| Calne, DB; Nygaard, TG; Snow, BJ; Takahashi, H | 2 |
| Cumming, P; Gjedde, A; Kuwabara, H; Léger, GC | 1 |
| Cedarbaum, JM; Evans, A; Gjedde, A; Guttman, M; Kuwabara, H; Léger, G; Reches, A | 1 |
| Bhatia, K; Brooks, DJ; Burn, DJ; Marsden, CD; Sawle, GV; Turjanski, N | 1 |
| Cumming, P; Evans, AC; Gjedde, A; Guttman, M; Kuwabara, H; Léger, GC; Yasuhara, Y | 1 |
| Bhatt, MH; Calne, DB; Nakamura, K; Nomoto, M; Okada, A; Osame, M; Snow, BJ | 1 |
| Fujiwara, T; Hatazawa, J; Ido, T; Itoh, M; Iwata, R; Kogure, K; Nagasawa, H; Saito, H; Seo, S; Watanuki, S | 1 |
| Snow, BJ | 1 |
| Cesaro, P; Defer, GL; Degos, JD; Fenelon, G; Gaston, A; Geny, C; Jeny, R; Keravel, Y; Monfort, JC; Nguyen, JP; Peschanski, M; Remy, P; Ricolfi, F; Samson, Y; Villafane, G | 1 |
| Belakhlef, A; Chaly, T; Dhawan, V; Eidelberg, D; Ishikawa, T; Mandel, F; Margouleff, C; Patlak, C; Robeson, W | 1 |
| Chaly, T; Dahl, JR; Dhawan, V; Eidelberg, D; Ishikawa, T; Mandel, F; Margouleff, C; Robeson, W; Spetsieris, P | 1 |
| Fukumura, T; Ichiya, Y; Kuwabara, Y; Masuda, K; Otsuka, M; Sasaki, M; Yoshida, T | 1 |
| Holden, JE; Ruth, TJ; Schulzer, M; Snow, BJ; Vingerhoets, FJ | 1 |
| Nahmias, C; Wahl, L | 1 |
| Belakhlef, A; Chaly, T; Dahl, R; Dhawan, V; Eidelberg, D; Ishikawa, T; Mandel, F; Margouleff, C; Robeson, W | 1 |
| Fukumura, T; Hosokawa, S; Ichiya, Y; Kato, M; Kuwabara, Y; Masuda, K; Otsuka, M; Sasaki, M; Yoshida, T | 1 |
| Antonini, A; Boecker, H; Conrad, B; Grafin von Einsiedel, H; Kruggel, F; Kuwert, T; Leenders, K; Weindl, A | 1 |
| Akiguchi, I; Fukuyama, H; Hanakawa, T; Kato, M; Kimura, J; Shibasaki, H | 1 |
| Babchyck, B; Chaly, T; Dhawan, V; Eidelberg, D; Ishikawa, T; Kazumata, K; Mandel, F; Margouleff, C; Neumeyer, J; Zanzi, I | 1 |
| Fujiwara, T; Ido, T; Itoh, M; Itoyama, Y; Iwata, R; Kimura, I; Nagasawa, H; Saito, H; Tanji, H | 1 |
| Itoh, M; Itoyama, Y; Nagasawa, H; Tanji, H | 2 |
| Calne, DB; de la Fuente-Fernández, R; Kishore, A | 1 |
| Brooks, DJ; Lees, AJ; Turjanski, N | 1 |
| Björklund, A; Brooks, DJ; Brown, R; Brundin, P; Gustavii, B; Hagell, P; Jahanshahi, M; Lindvall, O; Marsden, CD; Morrish, P; Odin, P; Quinn, NP; Rehncrona, S; Rothwell, JC; Sawle, G; Wenning, GK; Widner, H | 1 |
| Cumming, P; Gjedde, A; Reith, J | 1 |
| Ballinger, JR; Ichise, M | 1 |
| Bergmans, P; Booij, J; Stoof, JC; Tissingh, G; Van Royen, EA; Winogrodzka, A; Wolters, EC | 1 |
| Barrio, JR; Huang, SC; Phelps, ME | 1 |
| Calne, DB; Hashimoto, S; MacLeod, P; Rouleau, GA; Schulzer, M; Shinotoh, H; Silveira, I; Snow, BJ; Thiessen, B | 1 |
| Antonini, A; Günther, I; Leenders, KL; Maguire, RP; Missimer, J; Psylla, M; Vontobel, P | 1 |
| Bailey, DL; Brooks, DJ; Morrish, PK; Rakshi, JS; Sawle, GV | 1 |
| Bergman, JR; Haaparanta, MT; Laihinen, AO; Oikonen, VJ; Rinne, JO; Rinne, UK; Ruotsalainen, UH; Ruottinen, HM; Solin, OH | 1 |
| Cabaret, M; Caparros-Lefebvre, D; Godefroy, O; Petit, H; Rémy, P; Samson, Y; Steinling, M | 1 |
| Poewe, WH; Wenning, GK | 1 |
| Hardie, RJ | 1 |
| Brooks, DJ; Burn, DJ; Ceravolo, R; Maraganore, D; Piccini, P | 1 |
| Ashburner, J; Bailey, DL; Brooks, DJ; Friston, KJ; Ito, K; Morrish, PK; Rakshi, JS; Uema, T | 1 |
| Brooks, DJ; Piccini, P | 1 |
| Ashburner, J; Bailey, DL; Brooks, DJ; Dagher, A; Friston, KJ; Ito, K; Jenkins, IH; Morrish, PK; Rakshi, JS; Uema, T | 1 |
| Degueldre, C; Franck, G; Garraux, G; Laureys, S; Lemaire, C; Peigneux, P; Salmon, E | 1 |
| Morrish, PK | 1 |
| Bergman, J; Haaparanta, M; Nurmi, E; Portin, R; Rinne, JO; Ruottinen, H; Solin, O | 1 |
| Acorn, T; Dagher, A; Darvesh, S; Desrosiers, J; Gaudet, P; Hebb, A; Hong, M; King, D; Law, A; Mendez, I; Robertson, H; Weerasinghe, S | 1 |
| Calne, DB; de la Fuente-Fernández, R; Kishore, A; Mak, EK; Pal, PK; Ruth, TJ; Schulzer, M; Snow, BJ; Stoessl, AJ; Vingerhoets, FJ | 1 |
| Cumming, P; Deep, P; Evans, AC; Gjedde, AH; Kuwabara, H; Rousset, OG | 1 |
| Bergman, J; Haaparanta, M; Koskenvuo, M; Laihinen, A; Marttila, R; Rinne, JO; Rinne, UK; Ruottinen, H; Solin, O | 1 |
| Aebischer, P; Bloch, J; Brown, WD; Carvey, P; Chen, EY; Chu, Y; Déglon, N; Emborg, ME; Hantraye, P; Holden, JE; Kordower, JH; Leventhal, L; Ling, Z; Ma, SY; McBride, J; Palfi, S; Pyzalski, R; Roitberg, BZ; Taylor, MD; Trono, D | 1 |
| Azari, NP; Keel, A; Knorr, U; Leenders, KL; Ludin, HP; Maguire, RP; Nienhusmeier, M; Seitz, RJ; Weder, B | 1 |
| Bamborschke, S; Ghaemi, M; Heiss, WD; Rudolf, J; Schmülling, S | 1 |
| McGee-Minnich, L; Mink, JW; Moerlein, SM; Perlmutter, JS; Racette, BA; Videen, TO | 1 |
| Bergman, J; Eronen, E; Eskola, O; Niinivirta, M; Oikonen, V; Rinne, UK; Ruottinen, HM; Solin, O; Sonninen, P | 1 |
| Breeze, RE; Culver, S; Dillon, S; DuMouchel, W; Eidelberg, D; Fahn, S; Freed, CR; Greene, PE; Kao, R; Trojanowski, JQ; Tsai, WY; Winfield, H | 1 |
| Bergman, J; Eskola, O; Nurmi, E; Rinne, OJ; Ruottinen, HM; Solin, O | 1 |
| Ghaemi, M; Heiss, WD; Herholz, K; Hilker, R; Rudolf, J | 1 |
| Brooks, DJ; Chaudhuri, KR; Hajnal, JV; Herlihy, AH; Hu, MT; White, SJ | 1 |
| Bergman, J; Brück, A; Eskola, O; Kaasinen, V; Nurmi, E; Rinne, JO; Solin, O | 1 |
| Cumming, P; Danielsen, EH; Gjedde, A; Hermansen, F; Smith, D | 1 |
| Bergman, J; Haaparanta, M; Nurmi, E; Rinne, JO; Ruottinen, HM; Solin, O; Sonninen, P | 1 |
| Breeze, R; Chaly, T; Dhawan, V; Eidelberg, D; Fahn, S; Freed, C; Fukuda, M; Greene, P; Ma, Y; Nakamura, T | 1 |
| Bergman, J; Brück, A; Haaparanta, M; Laihinen, A; Lindell, A; Portin, R; Rinne, JO; Solin, O | 1 |
| Jankovic, J; Kapadia, AS | 1 |
| Stoessl, AJ | 1 |
| Bailey, DL; Brooks, DJ; Bryson, H; Ceravolo, R; Jorga, KM; Piccini, P | 1 |
| Broussolle, E; Guillouet, S; Thobois, S | 1 |
| de La Fuente-Fernández, R; Doudet, DJ; Holden, JE; McKenzie, J; Ruth, TJ; Sossi, V; Stoessl, AJ | 1 |
| Acorn, T; Dagher, A; Darvesh, S; Desrosiers, J; Gaudet, P; Hong, M; King, D; McAlister, V; Mendez, I; Robertson, H; Weerasinghe, S | 1 |
| Hedrich, K; Heiss, WD; Herholz, K; Hilker, R; Klein, C; Ozelius, LJ; Pramstaller, PP; Vieregge, P | 1 |
| Calne, DB; Fahn, S; Heiman, GA; Nygaard, TG; Snow, BJ; Takahashi, H | 1 |
| Brooks, DJ; Frackowiak, RS; Lees, AJ; Sawle, GV; Wroe, SJ | 1 |
| Brooks, DJ; Findley, LJ; Ibanez, V; Marsden, CD; Playford, ED; Sawle, GV; Thompson, PD | 1 |
| Bergman, J; Haaparanta, M; Laihinen, A; Rinne, JO; Rinne, UK; Ruotsalainen, U; Solin, O | 1 |
| Cedarbaum, J; Dhawan, V; Eidelberg, D; Fahn, S; Ginos, JZ; Greene, P; Moeller, JR; Rottenberg, DA; Sidtis, JJ; Strother, SC | 1 |
| Brooks, DJ; Frackowiak, RS; Jones, T; Leenders, KL; Marsden, CD; Perani, D; Sager, H; Salmon, EP; Tyrrell, P | 1 |
| Calne, DB; Johnston, RG; Martin, WR; McFarland, PA; McLean, DR; McPhee, MS; Petruk, KC; Schindel, DR; Wilson, AF; Witt, NJ | 1 |
| Barrio, JR; Hoffman, JM; Huang, SC; Mazziotta, JC; Melega, WP; Phelps, ME; Satyamurthy, N; Schneider, JS; Yu, DC | 1 |
| Hayden, MR; Martin, WR | 1 |
| Boyes, BE; Cumming, P; Martin, WR; McGeer, EG | 1 |
| Adam, MJ; Ammann, W; Bergstrom, M; Harrop, R; Laihinen, A; Martin, WR; Rogers, JG; Ruth, TJ; Sayre, CI; Stoessl, AJ | 1 |
| Chirakal, R; Firnau, G; Garnett, ES; Lang, AE; Nahmias, C | 1 |
24 review(s) available for fluorodopa f 18 and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
PET studies of cerebral levodopa metabolism: a review of clinical findings and modeling approaches.
Topics: Animals; Brain; Computer Simulation; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Humans; Levodopa; Parkinson Disease; Pharmacokinetics; Positron-Emission Tomography | 2009 |
Transcranial sonography in the premotor diagnosis of Parkinson's disease.
Topics: Dihydroxyphenylalanine; Humans; Motor Neurons; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Ultrasonography, Doppler, Transcranial | 2010 |
[Functional imaging: role for the diagnosis and therapeutic evaluation of Parkinson's disease].
Topics: Antiparkinson Agents; Brain Chemistry; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine Agents; Glucose; Humans; Nortropanes; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2010 |
[Nuclear medicine imaging in patients with Parkinson's syndrome: an update].
Topics: Animals; Brain; Dihydroxyphenylalanine; Disease Progression; Dopamine; Energy Metabolism; Fluorodeoxyglucose F18; Genetic Predisposition to Disease; Humans; Nerve Degeneration; Neurons; Parkinson Disease; Parkinsonian Disorders; Positron-Emission Tomography; Receptors, Dopamine; Regional Blood Flow; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2010 |
Do dopamine agonists or levodopa modify Parkinson's disease progression?
Topics: Animals; Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Dihydroxyphenylalanine; Disease Progression; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; Indoles; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Tropanes | 2002 |
Imaging studies in movement disorders.
Topics: Brain; Cocaine; Dihydroxyphenylalanine; Dopamine; Humans; Movement Disorders; Parkinson Disease; Predictive Value of Tests; Radiopharmaceuticals; Severity of Illness Index; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2003 |
Dyskinesias after transplantation in Parkinson's disease.
Topics: Animals; Brain Tissue Transplantation; Dihydroxyphenylalanine; Dyskinesias; Fetal Tissue Transplantation; Humans; Mesencephalon; Parkinson Disease; Putamen | 2002 |
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
The sensitivity of 18-fluorodopa positron emission tomography and magnetic resonance imaging in Parkinson's disease.
Topics: Brain; Diagnosis, Differential; Dihydroxyphenylalanine; Disease Progression; Humans; Magnetic Resonance Imaging; Parkinson Disease; Sensitivity and Specificity; Tomography, Emission-Computed | 2004 |
The role of radiotracer imaging in Parkinson disease.
Topics: Biomarkers; Biotransformation; Blood-Brain Barrier; Carbon Radioisotopes; Clinical Trials as Topic; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Forecasting; Humans; Iodine Radioisotopes; Neurons; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Receptors, Dopamine; Substantia Nigra; Tetrabenazine; Tomography, Emission-Computed, Single-Photon | 2005 |
Role of [18F]-dopa-PET imaging in assessing movement disorders.
Topics: Dihydroxyphenylalanine; Dopamine Agonists; Fluorine Radioisotopes; Humans; Parkinson Disease; Positron-Emission Tomography | 2005 |
[Advantages and limitations in the assessment of neuroprotective treatment of Parkinson's disease by functional imaging].
Topics: Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Parkinson Disease; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2005 |
Fluorodopa PET scanning in Parkinson's disease.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Humans; Parkinson Disease; Substantia Nigra; Tomography, Emission-Computed | 1996 |
[PET study of dopamine metabolism and dopamine D2 receptor in juvenile parkinsonism].
Topics: Age of Onset; Brain; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Glucose; Humans; Parkinson Disease; Receptors, Dopamine D2; Tomography, Emission-Computed | 1997 |
[PET study using 6-[18F]-fluorodopa in Parkinson's disease].
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Parkinson Disease; Tomography, Emission-Computed | 1997 |
Contributions of positron emission tomography to elucidating the pathogenesis of idiopathic parkinsonism and dopa responsive dystonia.
Topics: Brain; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Fluorine Radioisotopes; Humans; Neurons; Parkinson Disease; Tomography, Emission-Computed | 1997 |
Advances in imaging Parkinson's disease.
Topics: Brain Mapping; Dihydroxyphenylalanine; Humans; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Biological imaging and the molecular basis of dopaminergic diseases.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Cell Count; Dihydroxyphenylalanine; Dopamine; Haplorhini; Humans; Kinetics; Parkinson Disease; Putamen; Rodentia; Substantia Nigra; Tomography, Emission-Computed | 1997 |
The natural history of Parkinson's disease.
Topics: Cell Count; Dihydroxyphenylalanine; Disabled Persons; Disease Progression; Fluorine Radioisotopes; Humans; Parkinson Disease; Risk Factors; Substantia Nigra | 1998 |
Etiology of Parkinson's disease: contributions from 18F-DOPA positron emission tomography.
Topics: Dihydroxyphenylalanine; Discriminant Analysis; Environment; Follow-Up Studies; Humans; Parkinson Disease; Pedigree; Tomography, Emission-Computed; Twin Studies as Topic | 1999 |
PET studies and motor complications in Parkinson's disease.
Topics: Antiparkinson Agents; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dyskinesia, Drug-Induced; Fluorine Radioisotopes; Humans; Levodopa; Neural Pathways; Opioid Peptides; Parkinson Disease; Pulse Therapy, Drug; Putamen; Receptors, Opioid; Tomography, Emission-Computed | 2000 |
Assessing the integrity of the dopamine system in Parkinson's disease: how best to do it?
Topics: Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Neural Pathways; Parkinson Disease; Severity of Illness Index; Substantia Nigra; Tetrabenazine; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2001 |
Contributions of PET and SPECT to the understanding of the pathophysiology of Parkinson's disease.
Topics: Aging; Animals; Antiparkinson Agents; Basal Ganglia; Brain Tissue Transplantation; Cell Transplantation; Cerebrovascular Circulation; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine Agonists; Electric Stimulation Therapy; Fetal Tissue Transplantation; Forecasting; Genetic Predisposition to Disease; Humans; Iatrogenic Disease; Imagination; Ligands; Mesencephalon; Motor Activity; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Parkinson Disease; Parkinson Disease, Secondary; Parkinsonian Disorders; Radiopharmaceuticals; Rats; Receptors, Dopamine; Risk; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tremor | 2001 |
Cerebral glucose and dopa metabolism in movement disorders.
Topics: Animals; Brain; Deoxy Sugars; Deoxyglucose; Dihydroxyphenylalanine; Humans; Huntington Disease; Parkinson Disease; Tomography, Emission-Computed | 1987 |
21 trial(s) available for fluorodopa f 18 and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Striatal Blood-Brain Barrier Opening in Parkinson's Disease Dementia: A Pilot Exploratory Study.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Corpus Striatum; Dementia; Dihydroxyphenylalanine; Humans; Parkinson Disease; Prospective Studies | 2022 |
Biochemical and clinical effects of Whey protein supplementation in Parkinson's disease: A pilot study.
Topics: Amino Acids; Antiparkinson Agents; Brain; Dietary Supplements; Dihydroxyphenylalanine; Double-Blind Method; Female; Follow-Up Studies; Glutathione; Homocysteine; Humans; Male; Middle Aged; Parkinson Disease; Pilot Projects; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Severity of Illness Index; Soybean Proteins; Treatment Outcome; Whey Proteins | 2016 |
Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes.
Topics: Adult; Age Factors; Aged; Brain; Cell Transplantation; Dihydroxyphenylalanine; Dopamine; Double-Blind Method; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Movement; Neostriatum; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Sex Factors; Treatment Outcome | 2010 |
Comparison of dopamine turnover, dopamine influx constant and activity ratio of striatum and occipital brain with ¹⁸F-dopa brain PET in normal controls and patients with Parkinson's disease.
Topics: Case-Control Studies; Dihydroxyphenylalanine; Dopamine; Early Diagnosis; Female; Humans; Male; Middle Aged; Neostriatum; Occipital Lobe; Parkinson Disease; Positron-Emission Tomography; Reproducibility of Results; ROC Curve | 2011 |
A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: an 18F-dopa PET study.
Topics: Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Disease Progression; Fluorine Radioisotopes; Follow-Up Studies; Humans; Indoles; Levodopa; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 2002 |
Crossover study of (99m)Tc-TRODAT-1 SPECT and (18)F-FDOPA PET in Parkinson's disease patients.
Topics: Aged; Corpus Striatum; Cross-Over Studies; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Parkinson Disease; Putamen; Radiopharmaceuticals; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tropanes | 2003 |
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.
Topics: Adult; Aged; Brain Tissue Transplantation; Cell Survival; Dihydroxyphenylalanine; Dopamine; Double-Blind Method; Dyskinesias; Female; Fetal Tissue Transplantation; Functional Laterality; Humans; Male; Middle Aged; Neurons; Parkinson Disease; Substantia Nigra; Tomography, Emission-Computed; Treatment Outcome | 2003 |
[18F]fluorodopa uptake in the upper brainstem measured with positron emission tomography correlates with decreased REM sleep duration in early Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Brain Stem; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Neurotransmitter Agents; Parkinson Disease; Polysomnography; Sleep Wake Disorders; Sleep, REM; Tomography, Emission-Computed | 2003 |
A technique for standardized central analysis of 6-(18)F-fluoro-L-DOPA PET data from a multicenter study.
Topics: Algorithms; Antiparkinson Agents; Canada; Dihydroxyphenylalanine; Dopamine Agents; France; Germany; Humans; Image Interpretation, Computer-Assisted; Indoles; Levodopa; Parkinson Disease; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed; Treatment Outcome; United Kingdom | 2004 |
Levodopa effect on [18F]fluorodopa influx to brain: normal volunteers and patients with Parkinson's disease.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Blood-Brain Barrier; Body Fluid Compartments; Brain; Cerebellum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Drug Synergism; Female; Humans; Levodopa; Magnetic Resonance Imaging; Male; Metabolic Clearance Rate; Middle Aged; Parkinson Disease; Presynaptic Terminals; Putamen; Reference Values; Tomography, Emission-Computed | 2004 |
Cortical 6-[18F]fluoro-L-dopa uptake and frontal cognitive functions in early Parkinson's disease.
Topics: Aging; Cerebral Cortex; Cognition Disorders; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Severity of Illness Index; Statistics as Topic; Tissue Distribution | 2005 |
Dopamine storage capacity in caudate and putamen of patients with early Parkinson's disease: correlation with asymmetry of motor symptoms.
Topics: Aged; Brain; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Functional Laterality; Humans; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Reference Values; Sensitivity and Specificity; Time Factors | 2006 |
Improving influx constant and ratio estimation in FDOPA brain PET analysis for Parkinson's disease.
Topics: Brain; Brain Mapping; Dihydroxyphenylalanine; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Tissue Distribution | 2005 |
Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways.
Topics: Acetates; Acetylcholine; Acetylcholinesterase; Aged; Atrophy; Binding, Competitive; Brain; Brain Mapping; Dihydroxyphenylalanine; Dopamine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Neuropsychological Tests; Parkinson Disease; Piperidines; Positron-Emission Tomography; Synaptic Transmission | 2005 |
The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease.
Topics: Aged; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Drug Synergism; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Tomography, Emission-Computed | 1994 |
The rate of progression of Parkinson's disease. A longitudinal [18F]DOPA PET study.
Topics: Aged; Aging; Caudate Nucleus; Dihydroxyphenylalanine; Disease Progression; Humans; Longitudinal Studies; Middle Aged; Neostriatum; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1996 |
Striatal [18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitriles; Parkinson Disease; Tomography, Emission-Computed | 1995 |
Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study.
Topics: Aged; Caudate Nucleus; Cognition Disorders; Dihydroxyphenylalanine; Dopamine; Female; Frontal Lobe; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Predictive Value of Tests; Putamen; Reaction Time; Regression Analysis; Task Performance and Analysis; Tomography, Emission-Computed; Verbal Behavior | 2000 |
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
Topics: Adult; Age Factors; Aged; Brain; Brain Tissue Transplantation; Control Groups; Culture Techniques; Dihydroxyphenylalanine; Dopamine; Double-Blind Method; Female; Fetal Tissue Transplantation; Fluorine Radioisotopes; Humans; Male; Mesencephalon; Middle Aged; Neurons; Parkinson Disease; Severity of Illness Index; Tomography, Emission-Computed | 2001 |
Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease.
Topics: Adult; Age Factors; Aged; Dihydroxyphenylalanine; Double-Blind Method; Humans; Middle Aged; Parkinson Disease; Putamen; Substantia Nigra; Tomography, Emission-Computed | 2001 |
18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease.
Topics: Aged; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Caudate Nucleus; Cross-Over Studies; Dihydroxyphenylalanine; Dopamine; Enzyme Inhibitors; Humans; Middle Aged; Neostriatum; Neurons; Nitrophenols; Parkinson Disease; Putamen; Tolcapone; Tomography, Emission-Computed | 2002 |
160 other study(ies) available for fluorodopa f 18 and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Dihydroxyphenylalanine; Dopamine; Dopaminergic Neurons; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Substantia Nigra | 2021 |
Contralateral Posterior Putaminal
Topics: Corpus Striatum; Dihydroxyphenylalanine; Humans; Parkinson Disease; Positron Emission Tomography Computed Tomography; Putamen | 2021 |
Comparison of 18 F-DOPA and 18 F-DTBZ for PET/CT Imaging of Idiopathic Parkinson Disease.
Topics: Dihydroxyphenylalanine; Humans; Parkinson Disease; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography | 2022 |
Practically Defined Off-State Dyskinesia Following Repeated Intraputamenal Glial Cell Line-Derived Neurotrophic Factor Administration.
Topics: Dopamine; Dyskinesias; Glial Cell Line-Derived Neurotrophic Factor; Humans; Parkinson Disease; Retrospective Studies | 2023 |
Longitudinal assessment of social cognition in de novo Parkinson's disease patients and its relationship with dopaminergic innervation.
Topics: Dopamine; Emotions; Humans; Parkinson Disease; Social Cognition | 2023 |
Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson's disease.
Topics: Aged; Cohort Studies; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Humans; Male; Middle Aged; Olfaction Disorders; Parkinson Disease; Positron-Emission Tomography; Putamen | 2020 |
Intrastriatal gradient analyses of 18F-FDOPA PET scans for differentiation of Parkinsonian disorders.
Topics: Aged; Caudate Nucleus; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Neuroimaging; Parkinson Disease; Parkinsonian Disorders; Positron-Emission Tomography; Putamen; Retrospective Studies | 2020 |
Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations.
Topics: Adult; Aged; Case-Control Studies; Dihydroxyphenylalanine; Dopamine; Female; Gaucher Disease; Genetic Predisposition to Disease; Glucosylceramidase; Heterozygote; Homozygote; Humans; Longitudinal Studies; Male; Middle Aged; Mutation; Neostriatum; Parkinson Disease; Positron-Emission Tomography | 2020 |
Network degeneration in Parkinson's disease: multimodal imaging of nigro-striato-cortical dysfunction.
Topics: Aged; Case-Control Studies; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Neural Pathways; Parkinson Disease; Positron-Emission Tomography; Putamen; Substantia Nigra | 2020 |
Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder - A PET study.
Topics: Aged; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Morpholines; Norepinephrine; Parkinson Disease; Positron-Emission Tomography; Putamen; REM Sleep Behavior Disorder; Sensorimotor Cortex; Thalamus | 2020 |
Hemispheric Network Expression in Parkinson's Disease: Relationship to Dopaminergic Asymmetries.
Topics: Aged; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Nerve Net; Parkinson Disease; Positron-Emission Tomography | 2020 |
[18F] FDOPA PET may confirm the clinical diagnosis of Parkinson's disease by imaging the nigro-striatal pathway and the sympathetic cardiac innervation: Proof-of-concept study.
Topics: Aged; Corpus Striatum; Dihydroxyphenylalanine; Female; Heart Ventricles; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra; Sympathetic Nervous System; Ventricular Function, Left | 2020 |
Comparative Performance of 99mTc-TRODAT-1 SPECT/CT and 18F-FDOPA PET/CT Imaging in Patients With Parkinson's Disease, Parkinson-Plus Syndrome, and Essential Tremor.
Topics: Dihydroxyphenylalanine; Essential Tremor; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Parkinson Disease; Parkinsonian Disorders; Positron Emission Tomography Computed Tomography; Single Photon Emission Computed Tomography Computed Tomography; Tropanes | 2021 |
Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies.
Topics: Adult; Aged; Brain; Cross-Sectional Studies; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Female; Heterozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins | 2017 |
Cardiac sympathetic denervation predicts PD in at-risk individuals.
Topics: Aged; Biomarkers; Dihydroxyphenylalanine; Female; Heart Septum; Heart Ventricles; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Prodromal Symptoms; Prospective Studies; Risk Factors; Sympathetic Nervous System | 2018 |
The role of exposure to pesticides in the etiology of Parkinson's disease: a
Topics: Aged; Austria; Cohort Studies; Dihydroxyphenylalanine; Environmental Exposure; Female; Humans; Israel; Male; Middle Aged; Neostriatum; Parkinson Disease; Parkinson Disease, Secondary; Pesticides; Positron-Emission Tomography | 2019 |
Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson's Disease.
Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Glial Cell Line-Derived Neurotrophic Factor; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Randomized Controlled Trials as Topic | 2019 |
Utility of intrastriatal ratios of FDOPA to differentiate idiopathic Parkinson's disease from atypical parkinsonian disorders.
Topics: Diagnosis, Differential; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Neostriatum; Occipital Lobe; Parkinson Disease; Positron-Emission Tomography | 2013 |
Cognitive slowing in Parkinson's disease is related to frontostriatal dopaminergic dysfunction.
Topics: Aged; Choice Behavior; Cognition Disorders; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Reaction Time; Statistics, Nonparametric | 2013 |
A dual-tracer study of extrastriatal 6-[18F]fluoro-m-tyrosine and 6-[18F]-fluoro-L-dopa uptake in Parkinson's disease.
Topics: Brain; Dihydroxyphenylalanine; Disease Progression; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Levodopa; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Time Factors; Tyrosine | 2014 |
Parkinson's disease subtypes show a specific link between dopaminergic and glucose metabolism in the striatum.
Topics: Aged; Dihydroxyphenylalanine; Dopamine; Dopaminergic Neurons; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Retrospective Studies; Ventral Striatum | 2014 |
Dopaminergic function and intertemporal choice.
Topics: Adult; Aged; Antiparkinson Agents; Behavior, Addictive; Brain; Case-Control Studies; Caudate Nucleus; Delay Discounting; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Gambling; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine; Synaptic Transmission; Ventral Striatum; Young Adult | 2015 |
Brain (18)F-DOPA PET and cognition in de novo Parkinson's disease.
Topics: Aged; Case-Control Studies; Cerebral Cortex; Cognition; Dihydroxyphenylalanine; Dopaminergic Neurons; Executive Function; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Verbal Behavior | 2015 |
Relation of 18-F-Dopa PET with hypokinesia-rigidity, tremor and freezing in Parkinson's disease.
Topics: Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hypokinesia; Male; Parkinson Disease; Positron-Emission Tomography; Retrospective Studies; Tremor | 2016 |
Fluorodopa is a Promising Fluorine-19 MRI Probe for Evaluating Striatal Dopaminergic Function in a Rat Model of Parkinson's Disease.
Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Fluorine; Fluorine Radioisotopes; Fluorine-19 Magnetic Resonance Imaging; Male; Parkinson Disease; PC12 Cells; Rats; Rats, Wistar | 2017 |
A novel injectable formulation of 6-fluoro-l-DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson's disease.
Topics: Animals; beta-Cyclodextrins; Cell Line, Tumor; Chemistry, Pharmaceutical; Cysteine; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Neuroblastoma; Neuroendocrine Tumors; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Wistar | 2017 |
Dual time point method for the quantification of irreversible tracer kinetics: A reference tissue approach applied to [
Topics: Brain; Case-Control Studies; Caudate Nucleus; Dihydroxyphenylalanine; Discriminant Analysis; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Linear Models; Models, Theoretical; Parkinson Disease; Positron-Emission Tomography; Putamen; Reference Values; Time Factors | 2017 |
Comparative assessment of 6-[
Topics: Animals; Apomorphine; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Fluorine Radioisotopes; Image Processing, Computer-Assisted; Male; Neostriatum; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Stereotyped Behavior; Tyrosine | 2017 |
Direct comparison of FP-CIT SPECT and F-DOPA PET in patients with Parkinson's disease and healthy controls.
Topics: Adult; Aged; Brain; Case-Control Studies; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Sensitivity and Specificity; Sex Characteristics; Tomography, Emission-Computed, Single-Photon; Tropanes | 2009 |
Simple ratio analysis of 18F-fluorodopa uptake in striatal subregions separates patients with early Parkinson disease from healthy controls.
Topics: Aged; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Radionuclide Imaging; ROC Curve | 2009 |
Hypertension increases cerebral 6-18F-fluorodopa-derived radioactivity.
Topics: Aged; Brain; Dihydroxyphenylalanine; Female; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2009 |
Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: an 18F-dopa PET progression study.
Topics: Aged; Corpus Striatum; Dihydroxyphenylalanine; Female; Heterozygote; Humans; Longitudinal Studies; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra; Ubiquitin-Protein Ligases | 2009 |
Supplement neuroimaging movement disorders.
Topics: Diagnostic Imaging; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Movement Disorders; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2009 |
Elevated [(18)F]FDOPA utilization in the periaqueductal gray and medial nucleus accumbens of patients with early Parkinson's disease.
Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Nucleus Accumbens; Parkinson Disease; Periaqueductal Gray; Positron-Emission Tomography; Radiopharmaceuticals | 2010 |
Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo.
Topics: Acetylcholine; Aged; Brain; Brain Mapping; Dihydroxyphenylalanine; Dopamine; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lewy Bodies; Lewy Body Disease; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography | 2010 |
Gaucher disease ascertained through a Parkinson's center: imaging and clinical characterization.
Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Gaucher Disease; Glucosylceramidase; Humans; Male; Middle Aged; Mutation; Neuropsychological Tests; Olfaction Disorders; Parkinson Disease; Phenotype; Positron-Emission Tomography; Ultrasonography, Doppler, Transcranial | 2010 |
Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study.
Topics: Amino Acid Transport Systems, Neutral; Antiparkinson Agents; Biogenic Monoamines; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Levodopa; Longitudinal Studies; Male; Middle Aged; Norepinephrine; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Serotonin | 2011 |
Rate of 6-[18F]fluorodopa uptake decline in striatal subregions in Parkinson's disease.
Topics: Adult; Aged; Brain Mapping; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Female; Fluorine Radioisotopes; Humans; Linear Models; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 2011 |
Fuming over Parkinson disease: are welders at risk?
Topics: Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Globus Pallidus; Humans; Magnetic Resonance Imaging; Manganese Poisoning; Nervous System; Occupational Diseases; Parkinson Disease; Risk Assessment; Welding | 2011 |
Reduced uptake of [¹⁸F]FDOPA PET in asymptomatic welders with occupational manganese exposure.
Topics: Adult; Aged; Corpus Striatum; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Linear Models; Male; Manganese Poisoning; Middle Aged; Occupational Exposure; Parkinson Disease; Positron-Emission Tomography; Putamen; Substantia Nigra; Welding | 2011 |
Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio.
Topics: Brain Mapping; Brain Tissue Transplantation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Functional Laterality; Humans; Longitudinal Studies; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tomography, Emission-Computed, Single-Photon; Tropanes | 2011 |
A within-subject comparison of 6-[18F]fluoro-m-tyrosine and 6-[18F]fluoro-L-dopa in Parkinson's disease.
Topics: Aged; Brain; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Tomography, Emission-Computed; Tyrosine | 2011 |
Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy.
Topics: Aged; alpha-Synuclein; Autonomic Denervation; Dementia; Dihydroxyphenylalanine; Disease Progression; Dopamine; Dopaminergic Neurons; Gait Disorders, Neurologic; Hallucinations; Humans; Lewy Body Disease; Male; Neostriatum; Norepinephrine; Parkinson Disease; Radiopharmaceuticals; Shy-Drager Syndrome; Sympathetic Nervous System | 2012 |
Automated striatal uptake analysis of ¹⁸F-FDOPA PET images applied to Parkinson's disease patients.
Topics: Automation; Biological Transport; Dihydroxyphenylalanine; Female; Humans; Image Processing, Computer-Assisted; Male; Neostriatum; Occipital Lobe; Parkinson Disease; Positron-Emission Tomography; Retrospective Studies | 2011 |
[¹⁸F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [¹⁸F]FDOPA and [¹¹C]DASB PET study in Parkinson's disease.
Topics: Aged; Aniline Compounds; Biological Availability; Dihydroxyphenylalanine; Female; Humans; Male; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Raphe Nuclei; Serotonin Plasma Membrane Transport Proteins; Sulfides; Tissue Distribution | 2012 |
Brain monoamine systems in multiple system atrophy: a positron emission tomography study.
Topics: Aged; Biogenic Monoamines; Brain; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Multiple System Atrophy; Norepinephrine; Parkinson Disease; Positron-Emission Tomography; Serotonin | 2012 |
Reduced uptake of FDOPA PET in end-stage liver disease with elevated manganese levels.
Topics: Caudate Nucleus; Ceruloplasmin; Dihydroxyphenylalanine; End Stage Liver Disease; Hepatitis B; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Liver Cirrhosis, Alcoholic; Magnetic Resonance Imaging; Male; Manganese; Middle Aged; Parkinson Disease; Putamen; Radionuclide Imaging; Radiopharmaceuticals | 2012 |
Partial trisomy 4q associated with young-onset dopa-responsive parkinsonism.
Topics: Adult; Age of Onset; alpha-Synuclein; Antiparkinson Agents; Chromosomes, Human, Pair 4; Dihydroxyphenylalanine; Dopamine Agonists; Female; Gene Duplication; Humans; Intellectual Disability; Karyotyping; Levodopa; Magnetic Resonance Imaging; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Trisomy | 2012 |
Seasonality of striatal dopamine synthesis capacity in Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Seasons | 2012 |
Monosymptomatic resting tremor and Parkinson's disease: a multitracer positron emission tomographic study.
Topics: Adult; Aged; Brain; Cerebellum; Dihydroxyphenylalanine; Dominance, Cerebral; Energy Metabolism; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Putamen; Raclopride; Receptors, Dopamine D2; Reference Values; Tomography, Emission-Computed; Tremor; Up-Regulation | 2002 |
Effect of dopamine loss and the metabolite 3-O-methyl-[18F]fluoro-dopa on the relation between the 18F-fluorodopa tissue input uptake rate constant Kocc and the [18F]fluorodopa plasma input uptake rate constant Ki.
Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Reference Values; Severity of Illness Index | 2003 |
Neurotransmitter specificity of sympathetic denervation in Parkinson's disease.
Topics: Acetylcholine; Autonomic Fibers, Postganglionic; Cholinergic Fibers; Dihydroxyphenylalanine; Fluorine Radioisotopes; Heart Ventricles; Hemodynamics; Humans; Hypohidrosis; Hypotension, Orthostatic; Norepinephrine; Parkinson Disease; Radiopharmaceuticals; Sympathectomy; Tomography, Emission-Computed; Valsalva Maneuver | 2003 |
Young-onset Parkinson disease with and without parkin gene mutations: a fluorodopa F 18 positron emission tomography study.
Topics: Adolescent; Adult; Age of Onset; Aged; Corpus Striatum; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Ligases; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Substantia Nigra; Tomography, Emission-Computed; Ubiquitin-Protein Ligases | 2003 |
Correlation of dopamine transporter imaging with parkinsonian motor handicap: how close is it?
Topics: Activities of Daily Living; Aged; Brain; Cocaine; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Female; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neural Pathways; Neurologic Examination; Parkinson Disease; Sensitivity and Specificity; Substantia Nigra; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2003 |
Dopamine transporter imaging and SPECT in diagnostic work-up of Parkinson's disease: a decision-analytic approach.
Topics: Ambulatory Care Facilities; Brain; Cost-Benefit Analysis; Decision Trees; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Germany; Health Care Costs; Humans; Membrane Glycoproteins; Membrane Transport Proteins; National Health Programs; Nerve Tissue Proteins; Neurologic Examination; Parkinson Disease; Prospective Payment System; Referral and Consultation; Tomography, Emission-Computed, Single-Photon | 2003 |
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease.
Topics: Amphetamine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Central Nervous System Stimulants; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine Agonists; Functional Laterality; Immunohistochemistry; Levodopa; Male; Oxidopamine; Parkinson Disease; Propionates; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2004 |
Pharmacological and PET studies in patient's with Parkinson's disease and a short duration-motor response: implications in the pathophysiology of motor complications.
Topics: Adult; Age of Onset; Aged; Apomorphine; Biological Transport; Corpus Striatum; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Raclopride; Reaction Time; Tomography, Emission-Computed; Tritium | 2004 |
Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism.
Topics: Adult; Age of Onset; Aged; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Presynaptic Terminals; Receptors, Dopamine D2; Tomography, Emission-Computed; Ubiquitin-Protein Ligases | 2004 |
Cognitive- and motor-related regions in Parkinson's disease: FDOPA and FDG PET studies.
Topics: Biological Transport; Brain; Brain Mapping; Cognition; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Functional Laterality; Humans; Male; Middle Aged; Motor Activity; Parkinson Disease; Radiopharmaceuticals; Regression Analysis; Tomography, Emission-Computed | 2004 |
Changes of dopamine turnover in the progression of Parkinson's disease as measured by positron emission tomography: their relation to disease-compensatory mechanisms.
Topics: Brain; Dihydroxyphenylalanine; Disease Progression; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 2004 |
Prevalence of parkinsonism and relationship to exposure in a large sample of Alabama welders.
Topics: Adult; Age of Onset; Aged; Alabama; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Parkinson Disease; Positron-Emission Tomography; Prevalence; Psychomotor Performance; Radiopharmaceuticals; Severity of Illness Index; Videotape Recording; Welding | 2005 |
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.
Topics: Aged; Amino Acid Sequence; Animals; Dihydroxyphenylalanine; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Mutation; Parkinson Disease; Pedigree; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Serine | 2005 |
Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluorodopa F 18 activity.
Topics: Adult; Aged; Cohort Studies; Corpus Striatum; Dihydroxyphenylalanine; Disease Progression; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Nonlinear Dynamics; Parkinson Disease; Positron-Emission Tomography; Severity of Illness Index; Statistics, Nonparametric | 2005 |
Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Female; Functional Laterality; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Receptors, Dopamine; Task Performance and Analysis; Visual Cortex | 2005 |
Fluorodopa F 18 positron emission tomography and the progression of Parkinson disease.
Topics: Corpus Striatum; Dihydroxyphenylalanine; Disease Progression; Humans; Linear Models; Parkinson Disease; Positron-Emission Tomography; Tomography, Emission-Computed | 2005 |
The role of radiotracer imaging in Parkinson disease.
Topics: Brain; Dihydroxyphenylalanine; Disease Progression; Dopamine; Parkinson Disease; Patient Selection; Positron-Emission Tomography; Predictive Value of Tests; Tomography, Emission-Computed, Single-Photon | 2005 |
Corticostriatal covariance patterns of 6-[18F]fluoro-L-dopa and [18F]fluorodeoxyglucose PET in Parkinson's disease.
Topics: Aged; Cerebral Cortex; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Sex Factors | 2006 |
Age-related differences in levodopa dynamics in Parkinson's: implications for motor complications.
Topics: Adult; Age Factors; Age of Onset; Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 2006 |
[18F]FDOPA PET as an endophenotype for Parkinson's Disease linkage studies.
Topics: Adult; Aged; Aged, 80 and over; Consanguinity; Dihydroxyphenylalanine; Ethnicity; Family Health; Female; Fluorine Radioisotopes; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Humans; Lod Score; Male; Middle Aged; Parkinson Disease; Pedigree; Phenotype; Positron-Emission Tomography | 2006 |
Striatal subregional 6-[18F]fluoro-L-dopa uptake in early Parkinson's disease: a two-year follow-up study.
Topics: Aged; Corpus Striatum; Dihydroxyphenylalanine; Disease Progression; Dominance, Cerebral; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Reference Values | 2006 |
Striatal dopa and glucose metabolism in PD patients with freezing of gait.
Topics: Blood Glucose; Brain Mapping; Corpus Striatum; Dihydroxyphenylalanine; Dominance, Cerebral; Female; Fluorodeoxyglucose F18; Gait Apraxia; Humans; Male; Neurologic Examination; Occipital Lobe; Parietal Lobe; Parkinson Disease; Positron-Emission Tomography; Putamen | 2006 |
Long-term 24-hour duodenal infusion of levodopa: outcome and dose requirements.
Topics: Animals; Antiparkinson Agents; Cocaine; Dihydroxyphenylalanine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Duodenum; Humans; Indoles; Infusion Pumps; Levodopa; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Treatment Outcome | 2006 |
More to movement disorders than motion.
Topics: Basal Ganglia; Deep Brain Stimulation; Dihydroxyphenylalanine; Humans; Mental Disorders; Movement Disorders; Parkinson Disease; Positron-Emission Tomography | 2006 |
Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice.
Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Nortropanes; Parkinson Disease; Parkinsonian Disorders; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Substantia Nigra; Synaptic Transmission; Tyrosine | 2006 |
Regional metabolic changes in parkinsonian patients with normal dopaminergic imaging.
Topics: Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Ganglia; Humans; Male; Middle Aged; Multiple System Atrophy; Occipital Lobe; Parkinson Disease; Positron-Emission Tomography; Putamen; Retrospective Studies; Spinocerebellar Degenerations; Supranuclear Palsy, Progressive | 2007 |
Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model.
Topics: Antiparkinson Agents; Arousal; Brain; Brain Mapping; Diagnostic Imaging; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Movement; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon | 2006 |
Striatal dopaminergic activity (FDOPA-PET) associated with cognitive items of a depression scale (MADRS) in Parkinson's disease.
Topics: Aged; Brain Chemistry; Caudate Nucleus; Cognition Disorders; Corpus Striatum; Depressive Disorder; Dihydroxyphenylalanine; Disability Evaluation; Dopamine; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Putamen; Synaptic Transmission | 2007 |
Neurocirculatory and nigrostriatal abnormalities in Parkinson disease from LRRK2 mutation.
Topics: Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Baroreflex; Dihydroxyphenylalanine; DNA Mutational Analysis; Genetic Predisposition to Disease; Genotype; Heart; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Myocardium; Neostriatum; Neural Pathways; Parkinson Disease; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Reflex, Abnormal; Substantia Nigra; Valsalva Maneuver | 2007 |
18F-DOPA PET and PET/CT.
Topics: Brain; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Humans; Image Enhancement; Parkinson Disease; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed | 2007 |
[Evaluation of dopaminergic presynaptic function by [F-18] DOPA PET].
Topics: Dementia; Dihydroxyphenylalanine; Humans; Parkinson Disease; Positron-Emission Tomography; Presynaptic Terminals | 2007 |
Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss family.
Topics: Adult; Aged; Antiparkinson Agents; Brain; Chromosome Disorders; Dihydroxyphenylalanine; DNA Mutational Analysis; Female; Genes, Dominant; Humans; Levodopa; Male; Middle Aged; Mutation; Parkinson Disease; Pedigree; Phenotype; Positron-Emission Tomography; Radiopharmaceuticals | 2008 |
Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPA.
Topics: Attention; Benzazepines; Benzofurans; Brain Mapping; Carbon Radioisotopes; Cognition Disorders; Color Perception; Corpus Striatum; Dihydroxyphenylalanine; Discrimination Learning; Dopamine; Fluorine Radioisotopes; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Mental Status Schedule; Nerve Net; Neuropsychological Tests; Parkinson Disease; Pattern Recognition, Visual; Positron-Emission Tomography; Presynaptic Terminals; Problem Solving; Psychomotor Performance; Receptors, Dopamine D1; Synaptic Membranes | 2008 |
Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease.
Topics: Adult; Aged; Carbon Radioisotopes; Caudate Nucleus; Corpus Striatum; Deoxyglucose; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dopamine Antagonists; Energy Metabolism; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Raclopride; Receptors, Dopamine D2; Salicylamides; Tomography, Emission-Computed | 1995 |
Clinical and [18F] dopa PET findings in early Parkinson's disease.
Topics: Antiparkinson Agents; Case-Control Studies; Dihydroxyphenylalanine; Discriminant Analysis; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Predictive Value of Tests; Putamen; Selegiline; Severity of Illness Index; Time Factors; Tomography, Emission-Computed | 1995 |
Clinical correlates of [18F]fluorodopa uptake in five grafted parkinsonian patients.
Topics: Brain; Dihydroxyphenylalanine; Fetal Tissue Transplantation; Fluorine Radioisotopes; Graft Survival; Humans; Magnetic Resonance Imaging; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 1995 |
Personality correlates of [18F]dopa striatal uptake: results of positron-emission tomography in Parkinson's disease.
Topics: Aged; Arousal; Brain; Brain Mapping; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Personality; Tomography, Emission-Computed | 1995 |
Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease.
Topics: Biological Transport; Blood-Brain Barrier; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Fluorine Radioisotopes; Humans; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1995 |
[Presynaptic nigrostriatal function in Parkinson disease and Parkinson-plus syndromes. Comparative studies using positron emission tomography with L-6-(18F)fluorodopa].
Topics: Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine; Female; Fluorine Radioisotopes; Humans; Kinetics; Male; Middle Aged; Neural Pathways; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission; Tomography, Emission-Computed | 1994 |
Assessment of fetal tissue transplantation in Parkinson's disease: does PET play a role?
Topics: Animals; Brain Tissue Transplantation; Dihydroxyphenylalanine; Disease-Free Survival; Fetal Tissue Transplantation; Fluorine Radioisotopes; Humans; Neostriatum; Parkinson Disease; Tomography, Emission-Computed; Treatment Outcome | 1994 |
Metabolic topography of the hemiparkinsonism-hemiatrophy syndrome.
Topics: Adult; Atrophy; Brain; Deoxyglucose; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Syndrome; Tomography, Emission-Computed | 1994 |
Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism.
Topics: Adult; Aged; Dihydroxyphenylalanine; Disease Progression; Female; Humans; Male; Middle Aged; Parkinson Disease; Substantia Nigra; Tomography, Emission-Computed | 1994 |
Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease.
Topics: Brain Tissue Transplantation; Dihydroxyphenylalanine; Dopamine; Fetal Tissue Transplantation; Humans; Levodopa; Mesencephalon; Parkinson Disease; Putamen | 1994 |
Input functions for 6-[fluorine-18]fluorodopa quantitation in parkinsonism: comparative studies and clinical correlations.
Topics: Adult; Aged; Brain; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 1994 |
Positron emission tomographic studies of dopa-responsive dystonia and early-onset idiopathic parkinsonism.
Topics: Adolescent; Adult; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Prognosis; Tomography, Emission-Computed | 1993 |
Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans.
Topics: Adult; Arteries; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Parkinson Disease; Reference Values; Tomography, Emission-Computed | 1993 |
Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa.
Topics: Animals; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Nitriles; Parkinson Disease; Tomography, Emission-Computed | 1993 |
Comparison of striatal 18F-dopa uptake in adult-onset dystonia-parkinsonism, Parkinson's disease, and dopa-responsive dystonia.
Topics: Adult; Age Factors; Caudate Nucleus; Dihydroxyphenylalanine; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1993 |
Striatal L-dopa decarboxylase activity in Parkinson's disease in vivo: implications for the regulation of dopamine synthesis.
Topics: Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Humans; Kinetics; Middle Aged; Models, Biological; Parkinson Disease; Tomography, Emission-Computed | 1993 |
Clinical heterogeneity of dopa-responsive dystonia: PET observations.
Topics: Adult; Aged; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Receptors, Dopamine; Tomography, Emission-Computed | 1993 |
PET scan study on the dopaminergic system in a Japanese patient with hereditary progressive dystonia (Segawa's disease). Case report.
Topics: Corpus Striatum; Dihydroxyphenylalanine; Dystonia; Female; Humans; Japan; Levodopa; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed | 1993 |
6-[18F]fluorodopa metabolism in patients with hemiparkinsonism studied by positron emission tomography.
Topics: Adult; Aged; Aged, 80 and over; Caudate Nucleus; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Reference Values; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1993 |
Long-term outcome of unilaterally transplanted parkinsonian patients. I. Clinical approach.
Topics: Aged; Antiparkinson Agents; Brain; Brain Tissue Transplantation; Dihydroxyphenylalanine; Female; Fetal Tissue Transplantation; Fluorine Radioisotopes; Follow-Up Studies; Humans; Male; Mesencephalon; Middle Aged; Movement Disorders; Parkinson Disease; Treatment Outcome | 1996 |
Combined FDOPA and 3OMFD PET studies in Parkinson's disease.
Topics: Adult; Blood-Brain Barrier; Brain; Case-Control Studies; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Models, Biological; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 1996 |
Clinical significance of striatal DOPA decarboxylase activity in Parkinson's disease.
Topics: Brain; Case-Control Studies; Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Models, Biological; Parkinson Disease; Tomography, Emission-Computed | 1996 |
Nigrofrontal dopaminergic function as assessed by 18F-dopa PET.
Topics: Adult; Aged; Cerebellum; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Neural Pathways; Parkinson Disease; Substantia Nigra; Supranuclear Palsy, Progressive; Technology, Radiologic; Tomography, Emission-Computed | 1995 |
Reproducibility and discriminating ability of fluorine-18-6-fluoro-L-Dopa PET in Parkinson's disease.
Topics: Analysis of Variance; Brain; Case-Control Studies; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Male; Middle Aged; Parkinson Disease; Reproducibility of Results; Time Factors; Tomography, Emission-Computed | 1996 |
Modeling of fluorine-18-6-fluoro-L-Dopa in humans.
Topics: Adult; Biological Transport; Blood-Brain Barrier; Case-Control Studies; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Male; Middle Aged; Models, Biological; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 1996 |
Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis.
Topics: Adult; Aged; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Humans; Kinetics; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Quality Control; Sensitivity and Specificity; Tomography, Emission-Computed; Tyrosine | 1996 |
Differences in the reduced 18F-Dopa uptakes of the caudate and the putamen in Parkinson's disease: correlations with the three main symptoms.
Topics: Adult; Aged; Caudate Nucleus; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Movement Disorders; Muscle Rigidity; Parkinson Disease; Putamen; Tomography, Emission-Computed; Tremor | 1996 |
Secondary parkinsonism due to focal substantia nigra lesions: a PET study with [18F]FDG and [18F]fluorodopa.
Topics: Aged; Deoxyglucose; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Parkinson Disease; Substantia Nigra; Tomography, Emission-Computed | 1996 |
[A case of familial juvenile dystonia-parkinsonism: 18F-6-fluorodopa and 18F-fluoro-2-deoxyglucose PET study].
Topics: Adult; Age of Onset; Brain; Deoxyglucose; Dihydroxyphenylalanine; Dystonia; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glucose; Humans; Levodopa; Parkinson Disease; Tomography, Emission-Computed | 1996 |
Comparative nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Adult; Aged; Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1996 |
Brain 6-[18F]fluorodopa metabolism in early and late onset of Parkinson's disease studied by positron emission tomography.
Topics: Adult; Age of Onset; Aged; Brain; Case-Control Studies; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Presynaptic Terminals; Putamen; Radioligand Assay; Statistics, Nonparametric; Tomography, Emission-Computed | 1996 |
Dopaminergic function in patients with posttraumatic parkinsonism: an 18F-dopa PET study.
Topics: Aged; Brain; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Time Factors; Tomography, Emission-Computed; Wounds and Injuries | 1997 |
Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease.
Topics: Adult; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fetal Tissue Transplantation; Follow-Up Studies; Humans; Medical Records; Mesencephalon; Middle Aged; Parkinson Disease; Survival Analysis; Tomography, Emission-Computed; Treatment Outcome | 1997 |
Controversies arising from recent FDOPA articles.
Topics: Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Models, Biological; Parkinson Disease; Tomography, Emission-Computed | 1997 |
Physiologic modeling of PET data: quantitative conflict and challenge.
Topics: Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Models, Biological; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Nigrostriatal dopaminergic imaging with iodine-123-beta CIT-FP/SPECT and fluorine-18-FDOPA/PET.
Topics: Aging; Carrier Proteins; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Fluorodopa and raclopride PET analysis of patients with Machado-Joseph disease.
Topics: Adolescent; Adult; Caudate Nucleus; Cerebellum; Dihydroxyphenylalanine; Dopamine Antagonists; Female; Humans; Machado-Joseph Disease; Male; Middle Aged; Parkinson Disease; Putamen; Raclopride; Reference Values; Salicylamides; Tissue Distribution; Tomography, Emission-Computed | 1997 |
Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease.
Topics: Aged; Carbon Radioisotopes; Caudate Nucleus; Corpus Striatum; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Hypotension, Orthostatic; Male; Middle Aged; Multiple System Atrophy; Neurons; Parkinson Disease; Putamen; Raclopride; Radiography; Radiopharmaceuticals; Receptors, Dopamine D2; Regression Analysis; Salicylamides; Tomography, Emission-Computed | 1997 |
Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET.
Topics: Aged; Case-Control Studies; Caudate Nucleus; Dihydroxyphenylalanine; Disease Progression; Humans; Linear Models; Middle Aged; Parkinson Disease; Prospective Studies; Putamen; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Tomography, Emission-Computed | 1998 |
PET study and neuropsychological assessment of a long-lasting post-encephalitic parkinsonism.
Topics: Aged; Antiparkinson Agents; Brain; Dihydroxyphenylalanine; Encephalitis, Arbovirus; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Levodopa; Memory Disorders; Neuropsychological Tests; Obsessive-Compulsive Disorder; Parkinson Disease; Phobic Disorders; Tomography, Emission-Computed | 1998 |
Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F] dopa PET.
Topics: Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 1999 |
The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins.
Topics: Aged; Brain; Dihydroxyphenylalanine; Diseases in Twins; Female; Humans; Longitudinal Studies; Male; Middle Aged; Parkinson Disease; Radionuclide Imaging | 1999 |
Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease.
Topics: Adult; Brain; Brain Mapping; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 1999 |
Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study.
Topics: Biological Transport; Brain Mapping; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Frontal Lobe; Functional Laterality; Humans; Mesencephalon; Middle Aged; Parkinson Disease; Reference Values; Software; Tissue Distribution; Tomography, Emission-Computed | 1999 |
Fluorodopa uptake and glucose metabolism in early stages of corticobasal degeneration.
Topics: Aged; Basal Ganglia; Brain Diseases; Cerebral Cortex; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Nerve Degeneration; Parkinson Disease; Radiopharmaceuticals; Reference Values; Tissue Distribution; Tomography, Emission-Computed | 1999 |
Parkinson's disease in twins.
Topics: Dihydroxyphenylalanine; Diseases in Twins; False Negative Reactions; False Positive Reactions; Humans; Parkinson Disease; Predictive Value of Tests; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed | 2000 |
Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line--derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical considera
Topics: Aged; Brain Tissue Transplantation; Cell Count; Cell Line; Cell Survival; Dihydroxyphenylalanine; Dopamine; Feasibility Studies; Fetal Tissue Transplantation; Fluorine Radioisotopes; Follow-Up Studies; Graft Survival; Humans; Male; Mesencephalon; Middle Aged; Nerve Growth Factor; Neuroglia; Parkinson Disease; Putamen; Radiopharmaceuticals; Substantia Nigra; Tissue Preservation; Tomography, Emission-Computed; Treatment Outcome; Tyrosine 3-Monooxygenase | 2000 |
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations.
Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Motor Neurons; Movement Disorders; Parkinson Disease; Presynaptic Terminals; Substantia Nigra; Tomography, Emission-Computed | 2000 |
Effect of partial volume correction on estimates of the influx and cerebral metabolism of 6-[(18)F]fluoro-L-dopa studied with PET in normal control and Parkinson's disease subjects.
Topics: Adult; Aged; Algorithms; Brain; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Middle Aged; Models, Neurological; Parkinson Disease; Reference Values; Time Factors; Tissue Distribution; Tomography, Emission-Computed | 2000 |
Risk for Parkinson's disease: twin studies for the detection of asymptomatic subjects using [18F]6-fluorodopa PET.
Topics: Analysis of Variance; Dihydroxyphenylalanine; Female; Humans; Male; Parkinson Disease; Risk Factors; Tomography, Emission-Computed | 2000 |
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antigens, CD; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Female; Gene Expression; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Lentivirus; Macaca mulatta; Neostriatum; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Parkinson Disease; Parkinsonian Disorders; Psychomotor Performance; Substantia Nigra; Tyrosine 3-Monooxygenase | 2000 |
Disturbed functional brain interactions underlying deficient tactile object discrimination in Parkinson's disease.
Topics: Adult; Aged; Brain; Brain Mapping; Caudate Nucleus; Cerebrovascular Circulation; Dihydroxyphenylalanine; Discrimination, Psychological; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oxygen Radioisotopes; Parkinson Disease; Radiopharmaceuticals; Reference Values; Regional Blood Flow; Tomography, Emission-Computed; Touch | 2000 |
FDG- and Dopa-PET in postencephalitic parkinsonism.
Topics: Aged; Diagnosis, Differential; Dihydroxyphenylalanine; Female; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Parkinson Disease; Parkinson Disease, Postencephalitic; Radiopharmaceuticals; Reference Values; Tomography, Emission-Computed | 2000 |
Welding-related parkinsonism: clinical features, treatment, and pathophysiology.
Topics: Adult; Age of Onset; Aged; Case-Control Studies; Dihydroxyphenylalanine; Female; Humans; Male; Manganese; Middle Aged; Neostriatum; Occupational Diseases; Occupational Exposure; Parkinson Disease; Risk Factors; Tomography, Emission-Computed; Welding | 2001 |
Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging.
Topics: Aged; Antiparkinson Agents; Brain; Catechol O-Methyltransferase; Catechols; Dihydroxyphenylalanine; Female; Humans; Levodopa; Male; Middle Aged; Movement; Nitriles; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 2001 |
[(18)F]FDOPA and [(18)F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease.
Topics: Aged; Brain; Caudate Nucleus; Cocaine; Dihydroxyphenylalanine; Dopamine; Down-Regulation; Female; Fluorine Radioisotopes; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Presynaptic Terminals; Putamen; Synaptic Transmission | 2001 |
Increased pineal Fdopa uptake is related to severity of Parkinson's disease--a PET study.
Topics: Adult; Aromatic-L-Amino-Acid Decarboxylases; Biological Transport, Active; Case-Control Studies; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Melatonin; Middle Aged; Parkinson Disease; Pineal Gland; Tomography, Emission-Computed | 2001 |
A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson's disease.
Topics: Brain; Dihydroxyphenylalanine; Humans; Magnetic Resonance Imaging; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 2001 |
Increased frontal [(18)F]fluorodopa uptake in early Parkinson's disease: sex differences in the prefrontal cortex.
Topics: Aged; Dihydroxyphenylalanine; Disease Progression; Dopamine; Female; Functional Laterality; Humans; Male; Middle Aged; Neostriatum; Neurons; Parkinson Disease; Prefrontal Cortex; Sex Characteristics | 2001 |
Acute neuroleptic stimulates DOPA decarboxylase in porcine brain in vivo.
Topics: Animals; Antipsychotic Agents; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Female; Haloperidol; Neostriatum; Neurons; Parkinson Disease; Pharmacokinetics; Receptors, Dopamine D2; Swine; Tomography, Emission-Computed | 2001 |
Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study.
Topics: Adult; Aged; Caudate Nucleus; Dihydroxyphenylalanine; Disease Progression; Female; Follow-Up Studies; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed | 2001 |
Positron emission tomography shows that impaired frontal lobe functioning in Parkinson's disease is related to dopaminergic hypofunction in the caudate nucleus.
Topics: Adult; Caudate Nucleus; Cognition; Dihydroxyphenylalanine; Dopamine; Female; Fluorine Radioisotopes; Frontal Lobe; Humans; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 2001 |
Functional decline in Parkinson disease.
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Demography; Dihydroxyphenylalanine; Disease Progression; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Middle Aged; Multiple System Atrophy; Multivariate Analysis; Neurologic Examination; Parkinson Disease; Radiopharmaceuticals; Time Factors | 2001 |
Increase in dopamine turnover occurs early in Parkinson's disease: evidence from a new modeling approach to PET 18 F-fluorodopa data.
Topics: Aged; Brain; Dihydroxyphenylalanine; Discriminant Analysis; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Models, Biological; Parkinson Disease; Tomography, Emission-Computed | 2002 |
Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study. Report of three cases.
Topics: Cells, Cultured; Dihydroxyphenylalanine; Dominance, Cerebral; Dopamine; Feasibility Studies; Female; Fetal Tissue Transplantation; Follow-Up Studies; Humans; Male; Mesencephalon; Middle Aged; Neurologic Examination; Neurons; Parkinson Disease; Pilot Projects; Putamen; Stereotaxic Techniques; Substantia Nigra; Tomography, Emission-Computed | 2002 |
The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans.
Topics: Adult; Alleles; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Ligases; Middle Aged; Mutation; Parkinson Disease; Pedigree; Tomography, Emission-Computed; Ubiquitin-Protein Ligases | 2002 |
Long-term treatment response and fluorodopa positron emission tomographic scanning of parkinsonism in a family with dopa-responsive dystonia.
Topics: Adult; Aged; Brain; Child; Child, Preschool; Dihydroxyphenylalanine; Dystonia; Family; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pedigree; Tomography, Emission-Computed | 1992 |
The identification of presymptomatic parkinsonism: clinical and [18F]dopa positron emission tomography studies in an Irish kindred.
Topics: Adult; Caudate Nucleus; Dihydroxyphenylalanine; Family; Female; Fluorine Radioisotopes; Humans; Ireland; Male; Middle Aged; Parkinson Disease; Pedigree; Putamen; Tomography, Emission-Computed | 1992 |
Isolated tremor and disruption of the nigrostriatal dopaminergic system: an 18F-dopa PET study.
Topics: Adult; Aged; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Levodopa; Middle Aged; Parkinson Disease; Posture; Reference Values; Substantia Nigra; Tomography, Emission-Computed; Tremor | 1992 |
[18F]-6-fluorodopa PET scanning in Parkinson's disease after selective COMT inhibition with nitecapone (OR-462).
Topics: Adult; Aged; Catechol O-Methyltransferase Inhibitors; Catechols; Cerebellum; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Pentanones; Tomography, Emission-Computed | 1992 |
Detection of preclinical Parkinson's disease with PET.
Topics: Adult; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Diseases in Twins; Dopamine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Putamen; Reference Values; Tomography, Emission-Computed; Tremor | 1991 |
The metabolic anatomy of Parkinson's disease: complementary [18F]fluorodeoxyglucose and [18F]fluorodopa positron emission tomographic studies.
Topics: Adult; Brain; Deoxy Sugars; Deoxyglucose; Dihydroxyphenylalanine; Energy Metabolism; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Parkinson Disease; Tomography, Emission-Computed | 1990 |
The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease.
Topics: Aged; Carbon Radioisotopes; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Humans; Middle Aged; Nomifensine; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1990 |
Treatment of refractory Parkinson's disease with adrenal medullary autografts utilizing two-stage surgery.
Topics: Adrenal Medulla; Blood-Brain Barrier; Caudate Nucleus; Dihydroxyphenylalanine; Follow-Up Studies; Humans; Middle Aged; Parkinson Disease; Tomography, Emission-Computed; Transplantation, Autologous; Transplantation, Heterotopic | 1990 |
6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Fluorescent Dyes; Fluorine Radioisotopes; Macaca nemestrina; Male; Parkinson Disease; Parkinson Disease, Secondary; Putamen; Tomography, Emission-Computed | 1990 |
Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dystonia; Humans; Kinetics; Metabolic Clearance Rate; Parkinson Disease; Pyridines; Tomography, Emission-Computed | 1986 |
Positron emission tomography in Parkinson's disease: glucose and DOPA metabolism.
Topics: Adult; Aged; Blood Glucose; Brain; Caudate Nucleus; Cerebellum; Deoxyglucose; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Humans; Levodopa; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1987 |
A rostrocaudal gradient for aromatic acid decarboxylase in the human striatum.
Topics: Adolescent; Adult; Aging; Aromatic-L-Amino-Acid Decarboxylases; Child; Corpus Striatum; Dihydroxyphenylalanine; Dystonia; Female; Humans; Male; Parkinson Disease; Putamen; Tomography, Emission-Computed | 1987 |